Despite an increased EU role in the preparedness, monitoring and coordination of health emergencies over the past two decades, Member States’ responses to the first wave of COVID-19 were surprisingly uncoordinated. In light of calls to improve cooperation regarding future health emergencies, this article…

Developing robust and comprehensive analytical methods to size and quantify subvisible particles in biopharmaceutical products.

High throughput microscopy

Cationic peptide amphiphile nanoparticles are employed for co-delivery of immune modulator CpG and antigen. This results in better targeting to the antigen presenting cells and eliciting strong Th1 response, which is effective against the intracellular pathogens.

In order to gain a better insight into the basis of the rapid jasmonic acid (JA)-mediated stress response, an integrated approach using a targeted high-resolution mass spectrometry-based (HRMS) platform, was conducted to monitor the metabolism of JA using the model system of cell suspension cultures…

Subproject of

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn, Co-promotor: Dr. M.J.M. Schaaf

Putting our interns to work’ is the third-year slogan for the Master’s Programme in Medicine at Leiden University. After their regular residency periods, students are encouraged to find an internship in demanding sectors where they would like to work after completing their studies. In the MasterMindsChallenge,…

History lecturer Giles Scott-Smith is enthusiastic about the new pitch-to-peer programme (P2P), for which students have to make an original, creative assignment and evaluate one another’s work. This is part five in a series of articles about lecturers and innovation in teaching and learning.

Governance and Global Affairs, Institute of Security and Global Affairs

This PhD subproject concentrates on 16th-century ichthyology and takes Gessner’s Historia piscium (1558) (further HP) as its point of departure and focus.

The main question addressed in this thesis is how we can best conceive the contrast between a priori and empirical truths.

The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).

On the 12th of May, Stefan Norbruis successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Stefan on this achievement!

The lack of success of new CNS drugs in clinical development is in part due to the complexity of the CNS, unexpected side effects, difficulties for drugs to penetrate the brain, but also by the lack of biomarkers.

It is often said that the true character of a person is only revealed in a crisis. In these days, the coronavirus causes concern about the true state of the multilateral system. Political scientist Gisela Hirschmann (Leiden University) is worried about the future of multilateralism.

The aim of this project is to explore the use of statistical interaction models to quantify cross-omics and omics-drug interactions in large-scale clinical and experimental datasets

Lecture

In this dissertation the author digs into the constituent elements of River Plate tango in order to decode how specific musical materials were organized and combined by four outstanding musicians: Pugliese, Salgán, Piazzolla and Beytelmann.

Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)

The Leiden University Centre for Innovation and the Leiden University Medical Center (LUMC) have won the Surfnet Innovation Challenge. The team won the prize with an experiment to link a virtual 3D anatomical model to a living human body.

The aim of this work was to study the applicability of antigen-coated pH-sensitive microneedle arrays for effective vaccination strategies. Therefore, a model antigen (ovalbumin) was coated onto pH-sensitive (pyridine-modified) microneedle arrays to test pH-triggered antigen release by applying the…

How did the medieval manuscript develop as a physical object during the Twelfth Century Renaissance and what do these changes tell us about the intellectual culture of the period?

Promotor: Prof.dr. P. Hooykaas, Co-promotor: Dr. R. Offringa

In online games conflicts between players may arise. Novin, Bos, Stevenson and Rieffe investigated factors that may explain why some adolescents react more angrily than others in this type of situation. In their realistically designed gaming environment, the (pre-programmed) fellow player suddenly started…

How can innovation help or hinder public procurement processes?

In order to keep pace with the demands of the 21st century and its rapidly changing work environment, students and professionals need to display a new, specific range of qualities. To cope with the changing job market, you have to be resourceful, resilient and reflective.

A number of calls for proposals have been launched to finance innovative educational projects. An overview is given below.

Conference

On 7 May 2020, Jolanda van der Vliet defended her thesis 'The International Legal Protection of Environmental Refugees. A human rights-based, security and State responsibility approach'. The doctoral research was supervised by Prof. N.J. Schrijver and Prof. J.J.C. Voorhoeve.

The shift from response to recovery is now noticeable as the world moves past the paralyzing effects of the COVID-19 pandemic. This book explores responses to the pandemic by international, regional, and local institutions, multilateral action, and crisis prevention efforts at different levels of governance,…

Promotor: E.F. Smets Co-promotor: J. Geml

Kohei Suzuki is Assistant Professor at Institute of Public Administration. This study carries several important implications for understanding the policy impacts of a graying population and for studies of the welfare state, in general.

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

Dendritic cells (DC) play a prominent role in the priming of CD8(+) T cells. Vaccination is a promising treatment to boost tumor-specific CD8(+) T cells which is crucially dependent on adequate delivery of the vaccine to DC.

How did the Chinese in Indonesia respond to anti-Chinese violence and changing political conditions during the Indonesian revolution?

The potential of bioneedles to deliver influenza vaccines was investigated.

Feeling nostalgic, Professor in Public Administration Science Bernard Steunenberg explains how some years ago he would occasionally show a TV broadcast to his students, first removing the videotape from its big box and putting it in a VHS player. Today, a student from Maastricht, sitting in the train…

In this article Vanessa Newby discusses how the ANZUS states of United States, Australia, and New Zealand that sit on the fringes of the Asia-Pacific, are increasingly using their armed forces to deliver Humanitarian Aid and Disaster Response (HADR) as a way of engaging with the region.

The United Nations Office for Disarmament Affairs (UNODA) has published the 2017 issue in their Civil Society and Disarmament series, titled Voluntary, Non-Binding Norms for Responsible State Behaviour in the Use of Information and Communications Technology: A Commentary. The series aims to provide…

The eight ambitions of Leiden University's vision on education - Learning@LeidenUniversity - were the key theme of the packed Education Festival on 19 June. More than 200 lecturers and students came to PLNT, Leiden's innovation hotspot, for inspiration and best practices in the field of educational…

This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.

Broad universities that focus strongly on fundamental research have the best chance of contributing to economic innovations, for example in the life and data sciences. This is the message of Professor Simcha Jong in his inaugural lecture on 14 November.

The Master of Medicine at Leiden University Medical Center (LUMC) has won the national biennial award for best educational innovation in medical teaching. It was awarded the prize by the Netherlands Association for Medical Education (NVMO) for its MasterMinds Challenge (MMC).

Attachés from the Innovation Attaché Network (IAN) visited Leiden University to meet with researchers working on Artificial Intelligence (AI) and to become more familiar with what Leiden, Leiden University and the LUMC have to offer to possible partners abroad.