923 search results for “resistance” in the Public website
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Unilever Research Prize for master student Lukas Kiefer
Leiden Biology student Lukas Kiefer has won the Unilever Research Prize 2018 for his research into efficient production of a new antibiotic. Kiefer: ‘I want to make biological medicines available to people in need.'
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Unravelling the genes responsible for life history traits in the giant woody cabbage (Brassica oleracea)
Which genes are involved in woodiness and associated traits such as drought tolerance, flowering time, stem elongation, life span, and plant herbivory, and how do these gene regulatory pathways overlap?
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Cancer Therapeutics and Drug Safety
In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…
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Leiden Political Science Workshop: Mimetic Hedging - How Hezbollah Resists against the World
Lecture
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Country Meeting: Violent Resistance - Militia Formation and Civil War in Mozambique
Lecture
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The added risk of size
What are the risks of nanoparticles?
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Potentiation of Gram-positive specific antibiotics against Gram-negative bacteria through outer membrane disruption
Extending our current arsenal of antibiotics is key to staying ahead in the arms race between humans and resistant bacteria.
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Zumba
Founded in 2001, Zumba Fitness is a global lifestyle brand that fuses fitness, entertainment and culture into an exhilarating dance-fitness sensation! Zumba® exercise classes are " fitness-parties " that blend upbeat world rhythms with easy-to-follow choreography, for a total-body workout that feels…
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Growing up to be fearful?
Social evaluative fears during adolescence
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El presente incómodo: subjetividad en crisis y novelas cubanas después del muro
This book aims to understand cultural transitions and negotiations between art and politics from 1989 to 2020 through analysis of a series of Cuban novels.
- Prof Dr Matthias Erb
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Post-Soviet Nostalgia. Confronting the Empire's Legacies
Bringing together scholars from Russia, the United States and Europe, this collection of essays is the first to explore the slippery phenomenon of post-Soviet nostalgia by studying it as a discursive practice serving a wide variety of ideological agendas.
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Efficient and flexible platform to isolate and study bacteriophages
We aim to develop a microfluidic platform that can parallelize testing the performance and characteristics of pure, mixed and environmental bacteriophage samples.
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Hye Kyong Kim
PhD at the Natural Product Laboratory, Institute of Biology, Leiden University - the Netherlands
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Core cross-linked polymeric micelles based on polypept(o)ides: from secondary structure formation of polypeptides to functional cross-linking
This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.
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About the programme
In the Master's programme Crisis and Security Management, specialisation Governance of radicalism, extremism and terrorism we focus on the academic body of knowledge on different form of protests, contention, resistance and violence. We explore and explain the emergence of radical and extremist move…
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Dynamics of a β-lactamase
BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.
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Politics and Aesthetics
Politics and Aesthetics is one of the six research themes of the LUCAS Modern and Contemporary cluster.
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Unraveling the role of signaling networks controlled by Grainyhead like transcription factor in breast cancer subtypes
This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…
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Discovery of FLT3 inhibitors for the treatment of acute myeloid leukemia
The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.
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Dividing Worlds
Dividing Worlds: Tsunamis, Seawalls, and Ontological Politics in Northeast Japan
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Environmental and metabolomic study of antibiotic production by actinomycetes
Promotor: Prof.dr. G.P. van Wezel
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Paths through slavery: urban slave agency and empowerment in Suriname, 1700-1863
How did slaves in the eighteenth century manage to empower themselves and their kin, and why did this become all the more difficult in the nineteenth century?
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About the programme
The programme consists of 60 EC, to be completed in one year.
- Cold War
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From stress to success: how actinobacteria exploit life without a cell wall
The central question of this Vici proposal is to investigate if, and how actinobacteria exploit life without a cell wall.
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Nitric oxide in defence against mycobacterial infection
Can we enhance the capacity of host immune cells to kill mycobacteria via production of reactive nitrogen species?
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Towards a feminist playology: social sport studies and the limits of critique
The making of sacrifices seems part and parcel of any elite sportsperson’s life. Remarkably, the insights that we find in the current literature in social sport studies are not able to make sense of the references to sacrifice in the data that emerged in the context of this study on the social significance…
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Evolution & Biodiversity in Plant Sciences
Plant Sciences' contribution to the Evolution & Biodiversity research theme is to understand what are the key drivers of plant biodiversity during evolution with a focus on plant life history and resilience traits and develop tools to restore and maintain plant biodiversity.
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Leiden University Centre for International Relations
The Leiden University Centre for International Relations (LUCIR) is a multi-disciplinary platform promoting research and education on international relations at Leiden University.
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Mechanisms underlying the resistance of Human papillomavirus- infected or -transformed cells to Th1 immunity
PhD defence
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Discovery of Antibiotics and Their Targets in Multidrug-Resistant Bacteria
PhD defence
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Using mouse models to uncover genes driving tumorigenesis and therapy resistance in human breast cancer
PhD defence
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environmental factors determining heterogeneity in preservation stress resistance of Aspergillus niger conidia
PhD defence
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Resistance against the Achaemenid Empire: The Egyptian Rebellions of 521 and 487/86 BC
PhD defence
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Structural characterization of bacterial proteins involved in antibiotic resistance and peptidoglycan biosynthesis
PhD defence
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insertional mutagenesis to identify breast cancer drivers and therapy resistance genes in mice
PhD defence
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functional genetic screens to understand and overcome PARP inhibitor resistance
PhD defence
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
PhD defence
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The battle against antimicrobial resistant bacterial infections - next stage development of antimicrobial peptides
PhD defence
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Caribbean Connections: Cultural Encounters in a New World Setting (CARIB)
What socio-cultural transformations did indigenous communities in the Lesser Antilles undergo from the late precolonial to the early colonial period in response to Amerindian European-African cultural encounters? How did Amerindian populations realign themselves in response to the colonisation…
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Getting to the Core of Crimmigration. Assessing the Role of Discretion in Managing Intra-Schengen Cross-Border Mobility
To what extent are there differences between countries in and outside the European Union and the Schengen area in the level of crimmigration, the merger between migration control and crime control, and to what extent can these differences be explained by the way in which state and non-state actors in…
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Flow: A study of electron transport through networks of interconnected nanoparticles
This thesis describes a study from both a theoreticaL and an experimental point of view.
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Towards predictive cardiovascular safety: a systems pharmacology approach
Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski
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Retrieving the Past Glory: Social Memory, Transnational Networks and Christianity in Contemporary China
Jifeng Liu defended his thesis on 2 February 2017
- Green Infrastructure, Biodiversity and Ecosystem Services
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1,2-cis-glycosylations: method development and synthesis of complex oligosaccharides
Promotor: G.A. van der Marel, Co-promotor: D.C. Codée
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State, Society and Labour: A Social History of Iranian Textile workers, 1906-1941
This research investigates everyday lives and workplace experiences of Iranian workers employed at textile industry, which was the second biggest industry after oil following the latter’s discovery in 1908.
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Superlattices in van der Waals materials: A Low-Energy Electron Microscopy study
n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.
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Synthetic biology and genomics platform for new-to-nature bioactive peptides
Can the venom of snakes, scorpions and other animals be sources of new antibiotics?