856 search results for “pseudocontact shift” in the Public website
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PARAssign
Parassign is a program to assign protein nuclei solely on the basis of pseudocontact shifts (PCS). The PCS from several paramagnetic tags are required, in order to produce several restraints per nucleus.
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NMR studies of protein-small molecule and protein-peptide interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal
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Applications of paramagnetic NMR spectroscopy for protein research
The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.
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Classical and paramagnetic NMR spectroscopy applied to different protein systems
Promotor: Prof.dr. M. Ubbink
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Shifting the compass
Shifting the Compass: Pluricontinental Connections in Dutch Colonial and Postcolonial Literature
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Object shift in the Scandinavian languages: syntax, information structure, and intonation
This thesis discusses the constructions relevant to Object Shift from the intonational perspective, by presenting experimental data from all the Scandinavian languages.
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Shifting Identities - The Musician as Theatrical Performer
The focus of the research lies in the approach of reducing, denying, or taking away essential elements of music making in order to let the musician become theatrical.
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Bargaining in intrastate conflicts: The shifting role of ceasefires
It is widely known that conflict parties engage in ceasefires for a variety of reasons, but how do these reasons relate to the military and political aspirations of conflict party leaders?
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Direct and non‐linear innovation effects of demographic shifts
Kohei Suzuki, Assistant Professor at Institute of Public Administration, and two other authors researched the topic of innovation by governments in response to expected population decline.
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Post-Crimea Shift in EU-Russia Relations: From Fostering Interdependence to Managing Vulnerabilities
Ludo Block wrote the eleventh chapter of the book 'Post-Crimea Shift in EU-Russia Relations: From Fostering Interdependence to Managing Vulnerabilities'. His chapter 'Business as Usual? Police Cooperation under a Cloud of Political Animosity' can be found on page 204 of the book.
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Fungi of the greening Arctic: compositional and functional shifts in response to climatic changes
Promotor: E.F. Smets Co-promotor: J. Geml
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Big Data, Big Risks, Big Power Shifts: Evaluating the General Data Protection Regulation as an instrument of risk control and power redistribution
On 12 September 2019, Michiel Rhoen defended his thesis 'Big Data, Big Risks, Big Power Shifts: Evaluating the General Data Protection Regulation as an instrument of risk control and power redistribution in the context of big data'. The doctoral research was supervised by Prof. G.J. Zwenne and Prof.…
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DRIVE: A radical shift in understanding how extremism works
‘We want to say something very different from the norm. We are the radicals now.’ Tahir Abbas is lyric about the DRIVE project he will be leading from Leiden University in The Hague. This is a short introduction to the research that will be carried out in the Netherlands, Denmark, Norway and the United…
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Shift in scientific consensus about demise of Neanderthals
It is still unclear how the Neanderthals died out. For long, one theory seemed most likely: the emergence of the highly intelligent Homo sapiens, or modern humans. This competition hypothesis is no longer the dominant theory among scientists, research among archaeologists and anthropologists has shown.…
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Marginal Lands? The Commodification and Re-appreciation of Upland Agriculture in the Borderlands of Northeast India
How does the commodification and re-appreciation of the contiguous uplands of Northeast India, Bangladesh and Burma/Myanmar transform the relationship between these states and their upland citizens?
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‘Privacy is shifting from Big Brother to Kafka’
On the Day of Privacy, 28 January, the European Commission is calling on citizens to make sure they protect their personal data. But how do you do that, and against what, exactly? Privacy researcher Bart Custers explains.
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Microcoil MRI of Plants and Algae at Ultra-High Field: An exploration of metabolic imaging
This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).
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Riccardo Mancinelli
Science
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Blog Post | Recent shifts in diplomacy undermine China’s international standing
Over the past year and a half, China’s diplomacy has attracted attention from media institutions, policy makers and scholars around the globe.
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Healthy ageing? Shift the focus from the individual to the population
David van Bodegom, Professor of Vitality in an Ageing Population, will give his inaugural lecture on 11 November, also titled Vitality in an Ageing Population. According to Van Bodegom the key to healthy ageing is the lived environment. In the fight against lifestyle-related conditions, he therefore…
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Paradigm-shifting theory highlights the importance of substrate flexibility in enzymatic reactions
Leiden chemists have proposed a new model for enzymatic reactions, in which the flexibility of the substrate is much more important than previously thought. Their results are paradigm-shifting and could have major implications for drug research and enzyme engineering. Publication in Angewandte Chemi…
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Noisy Patterns: Bridging the gap between stochastics and dynamics
In this thesis, we study travelling waves in stochastic reaction-diffusion equations. We extend techniques from the deterministic theory for travelling waves to apply to the stochastic version, which allows us to compute the stochastic wave speed and shape, and draw conclusions on the stability of the…
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Urgent shifts in building practices are needed to tackle the global sand crisis
A rapid increase in the demand for construction sand is driving shortages and inequality around the world. Researchers from the Institute of Environmental Sciences at Leiden University have mapped the growing need for sand, as well as the bottlenecks and possible solutions. They have published their…
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Improvisations in phototrophy
Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.
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Shift 10 year anniversary Lustrum Gala
Alumni Event, Festival for students, employees and alumni
- Graduation Ceremony MSc Computer Science (2nd shift)
- Graduation Ceremony MSc Computer Science (1st shift)
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Religion Explored: Origin, Function and Meaning
How do ideas concerning the academic study of religion relate to the socio-cultural and political context in which they are developed?
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Study associations
The Faculty of Science has multiple study associations, which organise both study-related and social activities for students.
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Mapping pre-industrial sanitation infrastructure in the town of Haarlem
The central research question focuses on identifying shifts in the urban social network in terms of private, semi-public and public space by means of mapping the spatial distributions of wells and cesspits in the town of Haarlem in the course of the pre-industrial period (1200-1800). Shifts may be indicative…
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Algorithms for the description of molecular sequences
Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros
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Human Mobility in Archaeology
This third issue of Ex Novo gathers multidisciplinary contributions addressing mobility to understand patterns of change and continuity in past worlds; reconsider the movement of people, objects, and ideas alongside mobile epistemologies, such as intellectual, scholarly or educative traditions, rituals,…
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Medisch beroepsgeheim en de zorgplicht van de arts bij kindermishandeling in de rechtsverhouding tussen arts, kind en ouders
On 19 February 2019, Mirjam Sombroek-van Doorm defended her thesis 'Medisch beroepsgeheim en de zorgplicht van de arts bij kindermishandeling in de rechtsverhouding tussen arts, kind en ouders'. The doctoral research was supervised by Prof. dr. A.G. Castermans en Prof. mr. C.J.J.M. Stolker.
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Parallel evolution in an invasive plant species: evolutionary changes in allocation to growth, defense, competitive ability and regrowth of invasive
Promotor: Prof.dr. P.G.L Klinkhamer
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The ecological relevance of chemical diversity in plants: pyrrolizidine alkaloids in Jacobaea species
Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder
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More efficient learning thanks to sleep
Young children, adolescents and students may experience learning difficulties as a result of lack of sleep. Dr Kristiaan van der Heijden investigates sleep problems and solutions for various age groups.
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Variation and shift in a Papuan speech community
Lecture
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Mission adapted: the hidden role of governors in shaping central bank operating missions in Hungary
In this article, Makszin developed a conceptual framework for the operating mission of an independent Central Bank and traced changes in the operating mission of the Hungarian National Bank over its recent 27-year history together with Sebők and Simons. This study aims to understand the dynamics of…
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Thinking Difference between Heidegger and Levinas, Truth and Justice
Highlights the extent to which the two thinkers share a common philosophical framework, while also demonstrating how Levinas shifts the orientation of philosophical thinking from truth to justice.
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Sustaining the unsustainable? The political sustainability of pensions in Finland and the Netherlands
What makes a pension scheme sustainable? Most answers to this question have revolved around expert assessments of pension schemes’ affordability or adequacy. This study shifts focus from the financial or social sustainability of pension scheme designs to their political sustainability. The key question…
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Hyperimpressions
Towards a transdisciplinary and relational performance practice
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Novel factors modulating AGC kinase signaling-controlled polar auxin transport
The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.
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Garo: The Garo Ethnic Community
In this article, published in Brill’s Encyclopedia of the Religions of the Indigenous People of South Asia Online, Erik de Maaker posed three questions. How can the persistence of the community religion, albeit marginalized, be explained? What role is left for the practices, objects, and beliefs associated…
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Precarize and divide
Stella Morgana defended her thesis on 31 March 2021
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Negotiating Islamisation and resistance : a study of religions, politics and social change in West Java from the early 20th Century to the present
Chaider Bamualim defended his thesis on 9 September 2015
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The adoption of sound change
On the 13th of October, Cesko Voeten successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Cesko on this achievement!
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Markets, Ethics and Agency: Changing Land Utilization and Social Transformation in the Uplands of Northeast India
This project explores the decline of shifting cultivation in Northeast India. What is the impact on society of people’s deepening engagement with markets and the state?
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Shifting borders between the Indian Ocean and the Himalayan world
Lecture
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Lesson from Ukraine: Stop Appeasing Russia’s Trojan Horse, Serbia
Political Scientists Harun Cero and Arlinda Rrustemi (Leiden University) argue that the Russian invasion of Ukraine could present a chance for Bosnia and Kosovo to finally remove Russian influence, which has been growing and blocking these countries for years. The West should shift away from appeasing…
- Prof Dr Niklas Janz