1,197 search results for “product design engineering” in the Public website
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Leiden chemists improve electrochemical production of sustainable chemical building blocks
If you could convert CO2 into building blocks for other molecules with the help of electricity, you could make the chemical industry considerably more sustainable. Leiden chemists have unravelled a fundamental part of this process and applied this knowledge in a real device, as they write in Nature…
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Smart design carries sound one way
A new computer simulation shows the promising possibilities of the booming field of topology. Smartly designed mechanical structures carry sound exclusively one way and are immune to fabrication errors. Publication on 17 July in Nature Physics.
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Exploring the chemical space of post-translationally modified peptides in Streptomyces with machine learning
The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.
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Climate change poses threat to European electricity production
The vulnerability of the European electricity sector to changes in water resources is set to worsen by 2030 as a consequence of climate change. This conclusion is reached by researchers at Leiden University in an article published in Nature Energy this month.
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New software for designing sustainable cities
By 2050, more than 70 per cent of the world’s population will live in cities. A group of International researchers has developed software that shows city planners where to invest in nature to improve people’s lives and save billions of dollars.
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Controlling growth and morphogenesis of the industrial enzyme producer Streptomyces lividans
Promotor: Prof.dr. G.P. van Wezel, Co-Promotor: E. Vijgenboom
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Nicola Thome
Science
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Inhibiting protein production potentially a weapon against Alzheimer’s
Inhibiting specific protein production in the human body can serve as a crucial weapon in the fight against Alzheimer's, Eline van Maanen believes. PhD defence 23 November.
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
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Workshop Report: The Stigma of ‘Underdevelopment’ in Heritage Production
On Friday 11 October, the workshop on “The Stigma of ‘Underdevelopment’ in Heritage Production” took place in the beautiful building of the Faculty of Architecture and the Built Environment at Delft University of Technology. The workshop was organized by Jasmijn Rana (CADS) and John Hanna (TU Delft)…
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Cell-based medicinal products: grant rejected, paper published
Cell-based medicinal products (CBMPs) belong to an innovative and heterogeneous group of medicines called advanced therapy medicinal products (ATMPs). The limited analytical toolbox for CBMP characterization and release testing is one of the reasons why CBMP development is so challenging.
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PhD on research on an industrial production process
Computer scientist Bas van Stein conducted research at Tata Steel and BMW on how their production processes could be streamlined and optimised on the basis of data. As part of his research he developed some innovative products. PhD defence 20 September.
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NWO ECHO grant for research on fickle RNA production
Genes are active sometimes, and other times they remain dormant for a while. Leiden physicist John van Noort receives an NWO ECHO grant to find out how this happens.
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A psycholinguistic model for phonological development
In this research project child language phonology is studied from the perspective of a psycholinguistic speech-production model and this model is in turn studied from the perspective of developmental phonology.
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Terpenoids and terpenoid indole alkaloids in Catharanthus roseus cell suspension cultures
Promotor: Prof.dr. R. Verpoorte, Co-Promotores: N.R. Mustafa, A.E. Schulte
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Surprising productions at the Humanities Lab Film Festival
Humour, science and creativity. During the Humanities Lab Film Festival this came all together in the short films that the students of the Honours College Humanities have made in the last few weeks. “Working together with people of different studies is inspiring.”
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Publication on the design of multifunctionalized nanoparticles
Despite considerable progress in the design of multifunctionalized nanoparticles (NPs) that selectively target specific cell types, their systemic application often results in unwanted liver accumulation. The exact mechanisms for this general observation are still unclear.
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Career prospects
A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.
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New tenure track: understanding and engineering microbial metabolism for health and sustainability
On 1 March, Lennart Schada von Borzyskowski will start on a tenure track position at the Institute of Biology Leiden (IBL). With a focus on the natural and synthetic biochemistry of environmental bacteria, he wants to apply their features to health and sustainability issues.
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Abolfazl Sajadi
Science
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Cancer chess: molecular insights into PARP inhibitor resistance
The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…
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Call for participation: KABK Design / Research Club #2
You are warmly invited to join us for the second meeting of the KABK Design / Research Club, a forum for researchers from the KABK and Leiden University who are conducting research in, about, or through design-related disciplines.
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Alice Twemlow wins Simon Mari Pruys prize for design criticism
On Saturday November 16 Alice Twemlow was awarded the Simon Mari Pruys prize for design criticism for her essay ‘Conflicting Definitions of Key Terms’.
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Positive representations on ordered Banach spaces
Promotor: A. Doelman, Co-promotor: M.F.E. de Jeu
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Fault Lines Design/Research at KABK/Leiden University
Organized by the Lectorate Design Friday, December 14, 2018 KABK Auditorium 10:00-17:00
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XAIPRE - Explainable AI For Predictive Maintenance
The project XAIPre (pronounce “Xyper”) aims to develop predictive maintenance system for the maritime industry using sensor technology and artificial intelligence. The project aims at developing Explainable Predictive Maintenance (XPdM) algorithms that do not only provide the engineers with a prediction…
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signs international agreement on developing Advanced Therapy Medicinal Products
Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…
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Computer scientists from Leiden and Eindhoven optimise building designs
The design process of new buildings is extremely complex due to strict requirements. Computer models are used to create the designs. Scientists from LIACS developed advanced algorithms that help their colleagues at Eindhoven University of Technology to optimise these models.
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The Design of Principles and Guidelines for Out-of-Court Turnaround Professionals
In a project of INSOL Europe's Turnaround Wing, TRI Leiden is working on the design of Principles and Guidelines for Restructuring and Turnaround Professional. These Principles and Guidelines are designed for the out-of-court turnaround of a business in distress. This Report is the result of a study…
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Estimation and Optimization of the Performance of Polyhedral Process Networks
Promotor: E.F.A. Deprettere, Co-Promotor: A.C.J. Kienhuis
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Proposal on refugee crisis management wins student Research Design Conference
This year Elke Devroe and Moniek Akerboom organized a ‘Research Design Conference’ for students in the course ‘Research Design’ of the Master’s Crisis and Security Management (CSM). Each group competed in obtaining a (fictive) grant. Students learned to defend their proposal and make it attractive and…
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Nanowire based Tandem Solar Cells
In this project innovative technology for photovoltaics cells is developed and analysis of ecological and health related risks are explicitly accounted for.
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Engineering meaning
Lecture
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Willemijn Heeren
Faculty of Humanities
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Streptomyces as cell factories
We aim to engineer streptomycetes to fully exploit their potential for natural product productions, by a rational design and evolution approach.
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DANS KDP grant to publish five centuries of coin production figures
In the project ‘Coin production in the Low Countries: 1334-1789’, Leiden University, the International Institute of Social History, and Het Nederlands Economisch-Historisch Archief, team up to create a website that provides access to five centuries of coin production figures.
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Niels van der Windt
Science
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Martin Sievert
Faculty Governance and Global Affairs
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Anna Roseboom
Science
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Sem Grootscholten
Faculty Governance and Global Affairs
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Research on product safety and liability for AI by Gitta Veldt and Tycho de Graaf
A recently published article, Productveiligheid en aansprakelijkheid voor AI (Product Safety and Liability for AI), by Gitta Veldt and Tycho de Graaf examines the European Commission’s proposed Artificial Intelligence Regulation.
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Marie-leen Ryckaert
Faculty Governance and Global Affairs
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Scientists discover how to improve the production of antibiotics and enzymes in soil bacteria
A team of researchers at the Institute of Biology Leiden, in collaboration with scientists from Utrecht University, has discovered a novel approach to improve the production of antibiotics and enzymes in the soil bacteria Streptomycetes.
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Six modes of co-production for sustainability - Marja Spierenburg in Nature Sustainability
In a recent publication in Nature Sustainability, an international team led by Josephine Chambers from Wageningen University, and including Marja Spierenburg from the Institute of Cultural Anthropology and Development Sociology at Leiden University, have developed a practical tool for researchers and…
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Impact of plant hormones on growth and development of actinobacteria
Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.
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New insights into the production of antibiotics by bacteria
Bacteria use antibiotics as a weapon and even produce more antibiotics if there are competing strains nearby. This is a fundamental insight that can help find new antibiotics. Leiden scientists Daniel Rozen and Gilles van Wezel published their research results in the authoritative Proceedings of the…
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Call for papers: Power, Silence and the Production of History in Africa
The production of history is a process of power. This is particularly relevant in Africa, where during both the colonial and the post-colonial era history has been written by hegemonic regimes. This historiography has in turn (re-)produced structures of domination, social exclusion and division.…
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‘If we buy these imported products, we are co-responsible for the global decline in biodiversity’
What we buy and consume in Europe often has an impact on biodiversity somewhere else in the world. With a Horizon Europe Funding of 600.000 euros, assistant professor Laura Scherer and her team will develop models to look at the impact of global trade in non-food biomass. ‘After developing the models,…
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Group representations in Banach spaces and Banach lattices
Promotor: S.M. Verduyn Lunel, Co-promotores: M.F.E. de Jeu, B. de Pagter
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Solvent tolerance mechanisms in Pseudomonas putida
Bacterial biocatalysis constitutes a sustainable alternative for high-value chemicals production by enabling the utilization of renewable feedstocks.