Psycholinguistic research

Software development is probably not the first thing that comes to mind when you think of a sociologist. Three years ago, John Boy began developing his software package Textnets. Because of Corona, he was less able to concentrate on writing scientific research and also setting up the online courses…

This thesis describes the importance of being able to control the selectivity of potential drug candidates.

At the start of the COVID-19 pandemic, researchers from 15 departments at Leiden University Medical Center (LUMC) realised they could do more for patients if they joined forces. This is how the BEAT-COVID group has been able to rapidly gain knowledge about COVID-19, the role of the immune system and…

Environmental researcher Martina Vijver is over the moon with her ERC Consolidator Grant. This prestigious grant is recognition, she says, of the study of the behaviour and possible toxicity of new nanomaterials in ecosystems.

To argue that people can control the relative contributions of goal-driven and stimulus-driven processes to decision-making and action selection.

Inaugural Lecture

As part of the career orientation of the Master’s Vitality and Ageing, students visit various healthcare, policy and research organisations throughout the year. Students get introduced to relevant organisations where they have the possibility for a graduation internship and career opportunities. This…

Promotor: Prof.dr. H.A.G. Wijshoff

Debate

Debate

Promotor: Prof.dr. F.S. de Boer, Co-promotor: D. Clarke

‘I teach High Contrast Imaging, a 3 EC Masters course, and I co-teach Astronomical Telescopes and Instruments with Prof. C. Keller, a 6 EC masters course.'

Here you can find the (preliminary) schedules for the Minor SBI and the uSis codes for lecture & exam. Register for both, lecture and exam, 14 days before the course starts! Instructions for registrations, scroll down

PhD Defence

The Faculty Board issued these Regulations of the Institute of Philosophy on 9 January 2018.

Promotor: Prof. dr. A.G.G.M. Tielens

What are the historical roots of the indivisibility of pledge and hypothec?

All LIAS members and visitors are kindly requested to familiarize themselves with the information provided below, to the level of detail they feel is appropriate to their situation. This information overlaps in part with the University’s web pages on scientific integrity.

In this project, we aim to develop mathematical models to mechanistically and quantitatively predict the dynamics of cellular stress pathway activation and its relation with toxic effects when cells are exposed to various toxicants.

Pharmacologist Liesbeth de Lange has won the Lewis B. Sheiner Lecturer Award from the International Society of Pharmacometrics (ISoP). As Professor of Predictive Pharmacology she is working, among other things, on a mathematical model that can predict drug concentrations in the brain. On the occasion…

For many years, human rights have been considered a playing field in which states were the most important actors. It is they who in multilateral relations, such as the United Nations (UN), the World Trade Organisation (WTO) and the International Labour Organisation (ILO), have written international…

Which traits and/or trade-offs determine benefits of being deciduous or evergreen?

The SAPPAO project aims to optimise the accuracy and reliability of predicting scheduled flight times. The full name of the project is 'A Systems Approach towards Data Mining and Prediction in Airlines Operations'.

Instead of the finger scanner we now use a QR code based access system for the USC location.

Adverse drug reactions (ADRs) remain one of the major reasons for patient mortality and (early) drug withdrawal. Currently, different in vivo and in vitro models are used to assess the toxic potential of drugs in the pre-clinical phase. Unfortunately, the predictive value of this model does not fit…

Researchers at LED3 are working together with biopharmaceutical company Galapagos to develop software for use in early drug discovery (funded by NWO). This software is able to design molecules with several simultaneously optimized characteristics and will also take prediction reliability into consideration…

Machine Learning is becoming a more and more substantial technology for industry.

PhD Defence

Why is the swimming efficiency of the European eel higher than predicted?

PhD Defence

An overview of research projects at the Predictive Pharmacology group.

Lecture

Inaugural Lecture

Source: PLoS ONE, Volume 10, Issue 3 (2015)

I have studied the hot, diffuse gas around and between galaxies. Specifically, I have used the EAGLE numerical simulations of galaxy formation to predict the properties of this gas, and I have used those properties to predict specific observables: soft X-ray absorption and emission lines.

Make sure you are well prepared for your studies. Request a university ID card, find practical information for new students and learn about your rights and obligations. And how about learning a little Dutch?

Is is possible to better predict the validity of drug candidates?

Promotores: S.F. Portegies Zwart, E. M. Rossi

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

Source: Structure , Volume 22, Issue 8, pp. 1120-1139 (2014)

Promotoren: R. Tijdeman, A.K. Lenstra, Co-promotor: H.J.J. te Riele

From descriptive to physiological models that can predict oral absorption and elimination of CYP3A substrates across the pediatric age range.

Key publications of the Predictive Pharmacology group.