Recently, Ingrid Leijten’s book Core Socio-Economic Rights and the European Court of Human Rights was published with Cambridge University Press. The monograph was published in the series Cambridge Studies in European Law and Policy (edited by Laurence Gormley and Jo Shaw) and deals with the protection…

An important hormone excreting gland in the human body is the pituitary

This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.

Science, Institute of Environmental Sciences (CML)

Promotor: Prof.dr. S.F. Portegies Zwart, Co-promotor: D.C. Heggie

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

Systems pharmacology aims to apply techniques from systems biology to pharmacological models.

Citizens’s attitudes towards trade are not only about the (perceived) economic effect. Commerce also has a variety of security implications. Employing an original experiment, political scientists Matthew DiGiuseppe (Leiden University) and Katja Kleinberg (Binghamton University) demonstrate that security…

Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…

Dishoeck

In this article, Tokdemir & Klein examine the strategic actions of governments against domestic terrorist groups and domestic terrorist groups’ reactions to such actions.

Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher

High-throughput holistic preclinical screens are increasingly used in drug discovery, to assess both drug efficacy and drug safety.

How are carbohydrates processed by the immune system? Can carbohydrates be used to trigger T-cells against other conjugated antigens? Can they be used as adjuvants?

Promotor: G.A. Persoon, Co-promotor: H.H. de Iongh

Promotor: S.M. Verduyn Lunel

On the 23rd of March, Alessandro del Tomba successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Alessandro on this achievement!

Scientists often need to make sense of complex systems without knowing the important parameters or even without access to all the information. A collaboration of network theorists, including Diego Garlaschelli (IMT Lucca/Leiden), has now published a review article in the inaugural issue of Nature Reviews…

The experimental approach of science applied to artistic research

This project investigates the effects of the Asia-Pacific War (1931-1945) and the Korean War (1950-1953) on the production, distribution, preparation and consumption of food in transwar Japan and Korea.

On 29 January 2019, Robbert van Eijk defended his thesis 'Web Privacy Measurement in Real-Time Bidding Systems, A Graph- Based Approach to RTB system classification'. The doctoral research was supervised by Prof. dr. H.J. van den Herik.

Following their application to system biological models, control theory techniques have further potential to aid in the understanding and application of quantitative systems pharmacology models.

How can we explain that Caribbean small states have the most stable two-party systems in the world, while Pacific small states have either very weak parties or no parties at all? Matthew Louis Bishop (University of Sheffield, UK), Jack Corbett (University of Southampton, UK) and Wouter Veenendaal (Leiden…

Systems with local constraints is a new finding in recent researches on complex systems. The heterogeneous spatial interactions and the temporal dependencies among those numerous units make it difficult to describe by traditional statistical physics.

Promotores: W. Jiskoot, F. Ossendorp

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design. In this article, published on the website SAGE research methods, authors Jaroslaw Kantorowicz and Tobias M. Hlobil discuss how a Regression Discontinuity Design can be executed.

In this thesis we will explore the use of fuzzy systems theory for applications in bioinformatics.

We have studied the impact of particle shape anisotropy, multivalent interactions and flexibility on systems of micron-sized colloidal particles.

Tax scandals, like the Panama Papers, the Paradise Papers, and the Pandora Papers, have made taxation a major topic of public debate. Learn more about this in the new minor Tax and Society: Building a Sustainable and Fair Tax System.

In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.

We have developed a microfluidic platform for complex 3D organotypic cell cultures (so-called organ-on-a-chip systems) which are suited for integration in 96 or higher well plate format.

In the hunt for a vaccine against cervical cancer, fundamental knowledge about the immune system and organic chemistry have been brought together and have already resulted in a vaccine that is now being tested in clinical trials. Scientists are now working hard on an improved variant.

Promotor: Prof.dr. J. Kuiper

What is the environmental impact of different waste collection systems across Europe? How can the collection be improved when considering collection, sorting, and treatment, as well as use options for secondary materials?

Pathways of toxicity

In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.

Knowledge and culture subproject 2:

In autoimmune diseases such as rheumatism and diabetes the immune system attacks autologous proteins. Leiden researchers are trying to discover how this comes about.

Many people in the Netherlands have difficulty managing on their income. Professor by special appointment Wilco van Dijk, affiliated to Leiden University and Nibud, is researching what we can do to gain a healthier approach to managing our finances. His inaugural lecture is on 1 April.

Science, Leiden Institute of Advanced Computer Science (LIACS)

The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).

Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma