The aim of current study was to develop a dried inactivated polio vaccine (IPV) formulation with minimal loss during the drying process and improved stability when compared with the conventional liquid IPV.

This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.

In the near future oral polio vaccine (OPV) will be replaced by inactivated polio vaccine (IPV) as part of the eradication program of polio. For that reason, there is a need for substantial amount of safe and more affordable IPV for low-income countries. Bioneedles, which are biodegradable mini-implants,…

PURPOSE: The aim of the study was to develop a cheap and fast method to produce hollow microneedles and an applicator for injecting vaccines into the skin at a pre-defined depth and test the applicability of the system for dermal polio vaccination.

Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

Pim Schipper has won the third prize for his oral presentation during the tenth biennial meeting of the Globalization of Pharmaceutics Education Network (GPEN), which was held from 27 – 30 Aug 2014 at the University of Helsinki, Finland.

Current research at the Skin Barrier and Vaccination group.

Monika Baar started working in Leiden in September 2015. She's currently the project leader of the ERC Research Project 'Rethinking Disability'.

Vaccines are an extraordinary category of biopharmaceuticals. They are usually prophylactic and come in many types, from whole bacteria to peptides and nucleic acids. They are very cost effective and almost every human on the planet is vaccinated. The latter mandates that vaccines have to be extremely…

The quality of vaccines is still often tested by using laboratory animals. That has to change, according to researchers from Leiden University and the vaccinological institute Intravacc. Together they went searching for a test method that makes animal testing unnecessary. The first promising results…

Patients who feel understood will recover faster. But how can doctors become more empathetic? By reading literary works, suggests emeritus Leiden Professor of Medical Psychology, Ad Kaptein. He discusses this issue in his book ‘Helende woorden – romans over ziek-zijn’ (Healing words - novels about…

PhD Defence

Recent publications

Overview of the publications of the department of Industrial Ecology (1982-2015)