4 search results for “plasmodium falciparum” in the Public website
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Proteochemometric modelling coupled to in silico target prediction
An integrated approach for the simultaneous prediction of polypharmacology and binding affinity/potency of small molecules.
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CRISPR/Cas9 genetic modification of Plasmodium falciparum and transgenic parasites in malaria vaccine research
PhD Defence
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Safety and efficacy after immunization with Plasmodium falciparum sporozoites in the controlled human malaria infection model
PhD Defence
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First clinical trial with genetically modified malaria vaccine completed
In an innovative study, Radboudumc and LUMC jointly tested a candidate vaccine based on a genetically weakened malaria parasite. The results of this clinical trial, published in Science Translational Medicine, show that the vaccine is safe and elicits a defense response against a malaria infection.