What is the role of stress and stress-related hormones in emotion regulation?

Development of micro-scale analytical tools to be used to address relevant biomedical questions in the field of neuroscience, and other application areas intrinsically dealing with small sample amounts.

We are interested in the efficacy and safety of new drugs and novel means to decipher these aspects. Hence, we employ advanced imaging and high-throughput screening techniques next to computational approaches such as chem- and bioinformatics.

The Biomedical Microscale Analytics group is led by Dr. Rawi Ramautar. In present-day metabolomics, and bioanalysis in general, the analytical toolbox used encounters difficulties for the analysis of limited amounts of biological samples. As a result, a significant number of crucial biomedical/clinical…

Faster development of efficacious medicines; that is the goal of molecular pharmacologist Maarten Doornbos of the Leiden Academic Centre for Drug Research. He wants to find out which mechanisms influence the binding of drugs to a promising drug target in the body. That way, it will become easier to…

The research master's specialisation Developmental Psychology consists of five main parts: the general courses, the specialisation-specific courses, the elective courses, a research internship and a thesis.

The Leiden Ethnosystems and Development Programme (LEAD) of the Faculty of Science of Leiden University has been involved since 1987 in several Projects and Programmes in policy-based Training & Research, as well as in International Exhibitions, in Sub-Saharan Africa, Southeast Asia and the Mediterranean…

The Netherlands Organisation for Scientific Research (NWO) comprises several units. Eight Divisions for Sciences develop new research programmes, assess subsidy requests and monitor projects that NWO finances. ALW- Earth and Life Sciences is one of NWO’s eight Divisions for Science. Professor Melly…

Tuesday May 24th, the LACDR Annual Spring Symposium was held.

PhD student of the division Pharmacology, Jantine Brussee has won the second prize of the Figon-Pfizer PhD student Competition, at the Dutch Medicine Days in Ede.

What is the best method and time to test the effectiveness of medicines? PhD student Rob van Wijk of the Leiden Academic Centre for Drug Research (LACDR) discovered zebrafish larvae are best used in drug research when they are five days old. His findings were published on 15 February in the journal…

In order to better understand the course of Alzheimer’s disease, Frédérique Kok believes that a strategic and structured approach is needed: the Mastermind research approach. With her LUF grant, Kok wants to generate high-quality data to build a mathematical model that can recognize the onset of the…

Not taking into account the saturation of drug targets can lead to wrong conclusions about the duration of a drug's action. This is what former PhD candidate Wilbert de Witte writes together with the Leiden professors of pharmacology Meindert Danhof, Piet van der Graaf, and Liesbeth de Lange in Nature…

The €6.24 million EU-funded research project QSPainRelief has kicked off. The project aims to help patients suffering from chronic pain with novel, personalised combinational treatments and is coordinated by Elizabeth de Lange from the Leiden Academic Center for Drug Research.

Leiden pharmacy and pharmacology has risen to 17th place in the QS World University Rankings by Subject. In 2016 it was in 21st place in this annual ranking of leading universities in 46 disciplines.

As part of the HTSM2017 funding program, the LACDR division for Systems Biomedicine and Pharmacology received 1.08 million euros for a research project to develop novel engineering approaches to fight cancer.

The receptor nomenclature committee of IUPHAR, the International Union of Pharmacology, has several subgroups. Among these are a few that our division is involved in, those for adenosine, nicotinic acid, and GnRH receptors.

The Oncode Institute is a new international network organisation that focuses on making sure that new scientific findings on cancer are implemented in patients as rapidly as possible. Two young female researchers at Leiden University have been selected to join Oncode: Laura Heiman (Leiden Academic…

During the annual LACDR Spring Symposium, the audience chose PhD student Rob van Wijk as best speaker. Furthermore, six PhD students won a poster prize. Matthias P. Mayer of Heidelberg University opened the symposium with a keynote lecture about chaperone proteins.

An overview of awards and prizes granted to our staff and students in 2018, as well as special appointments and royal distinctions.

A recent publication by Biopharmaceutics PhD-candidate Eva Kritikou has been accepted by the renowned scientific journal Scientific Reports.

The Faculty of Science is pleased to invite you on Friday 17 April to the opening event of the Leiden Metabolomics Facility with a mini symposium.

Annelot van Esbroeck-Weevers, PhD student at the Molecular Physiology research group at the Leiden Institute of Chemistry, headed by Dr. Mario van der Stelt, has been awarded the Best Oral Communication Prize at the 8th European Workshop on Cannabinoid Research, held from 31 August to 2 September 2017…

Laura Heitman has been awarded a VIDI grant for her innovative drug research. Heitman strives to optimize a drug’s binding kinetics at its target in order to ultimately fight diseases effectively. She even pleads for a paradigm shift in drug discovery.

Matthias Barz has been appointed full Professor of Biotherapeutics Delivery at the Leiden Academic Centre for Drug Research (LACDR).

Lecture

An overview of the research at the Cancer Dug Target Discovery group.

The master’s programme Vitality and Ageing trains its students to become academic Vitality and Ageing professionals and engaged citizens who are competent and trained internationally and interdisciplinary. They are able to contribute to solutions for the challenges facing our ageing society.

The application procedure is broken down into three parts.

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The major aim is to unravel the central mechanisms of how peoples’ expectancies affect physical symptoms, immune and endocrine responses, and related health outcomes, through the use of pioneering multidisciplinary methods in experimental studies in healthy and clinical populations.

Leiden University is among the top 100 universities in four prominent international rankings.

Science, Leiden Academic Centre for Drug Research (LACDR)

The University Libraries provide access to a wealth of information: from e-journals, e-books and databases to printed material. The libraries are more than just a gateway. As a service organization we also help researchers find information, manage their data, assess the best places to publish their…

Within minutes after administration, most nanoparticles that were intended to deliver drugs to specific tissues will have disappeared from the blood. Jeroen Bussmann showed that they are destroyed by specialised scavenger cells in liver blood vessel walls, and found a way to prevent this. His publication…

Research facilities within reach of LIBC members:

Organ-on-chip technology is used in drug research and customized treatments for patients. Research Institutes and industry join forces within the Institute for human Organ and Disease Model Technologies (hDMT) that was officially launched on May 18. Combining facilities, people and expertise will allow…

Leiden University Libraries (UBL) has been able to acquire four remarkable medical manuscripts partly thanks to support from the Friends of Leiden University Libraries, the Pieter van Foreest Stichting and the Van de Sande Fonds. All four are largely written in Dutch and can be dated between 1595 and…

Lecture

Conference

Science, Leiden Academic Centre for Drug Research (LACDR)

Science, Leiden Academic Centre for Drug Research (LACDR), Leiden Institute of Chemistry (LIC)

Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…

On Monday the 8th of December, the annual symposium of the IBL will be organized at the main building of the LUMC Leiden. This year’s theme is “Integrative Biology towards Healthy Communities”.

Researchers at Leiden University have made a breakthrough in the study of the hereditary Pompe disease. Together with colleagues in York, they have developed a molecule that binds to the enzyme that is key to the progress of the disease. The findings have been published in ACS Central Science.

From the Republic of Moldova to Italy and from Indonesia to Greece, students from all over the world participated in the Bio-Pharmaceutical Science Summer School 2017. The students got a comprehensive overview of the education and research performed within the LACDR. ‘I am very happy to be here,’ says…

Professor Elizabeth de Lange was honoured on 31 January by the University of Uppsala, which appointed her Honorary Doctor at the end of 2019. During the ceremony, De Lange received all three symbols of honour for an Honorary Doctorate: a hat, a diploma, and a ring. ‘An incredibly wonderful experienc…