502 search results for “pbpk modelling” in the Public website
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Development of novel anti-cancer strategies utilizing the zebrafish xenograft model
PhD defence
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The use of a battery of evoked pain models in early phase drug development
PhD defence
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LTF Lecture with Mieke Boon: How do models represent? The role of perspectives
Lecture
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Lost in barbarian translation: The anchoring function of the Greek models and the poetics of innovation in Plautine comedy
PhD defence
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Modeling the areal diffusion of Chinese dialects: A case study of Suzhou Wu Chinese and its sub-varieties
Lecture
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LCN2 Seminar: Mathematical Modeling of Embryonic Development: The Intra- and Extracellular Networks that Coordinate Collective Cell Behavior
Lecture
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Lunchtime Speaker Series: MacBERTh: A Historically Pre-Trained Language Model for English (1450-1950)
Lecture
- Modelling Multidimensional Narratives and the Object Oriented Fox: What Lies Beyond Digitized Text in Textual Scholarship?
- sites in heterogeneous catalysis via structure-dependent microkinetic modeling
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‘Test medicines after five days’
What is the best method and time to test the effectiveness of medicines? PhD student Rob van Wijk of the Leiden Academic Centre for Drug Research (LACDR) discovered zebrafish larvae are best used in drug research when they are five days old. His findings were published on 15 February in the journal…
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A game of Mastermind to unravel Alzheimer’s disease
In order to better understand the course of Alzheimer’s disease, Frédérique Kok believes that a strategic and structured approach is needed: the Mastermind research approach. With her LUF grant, Kok wants to generate high-quality data to build a mathematical model that can recognize the onset of the…
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Facts about water: local knowledge, scientific models and societal conflict regarding dams and fracking
Lecture, First Water Talk of the Water and Society Lab
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Mechanistic insight and rAAV assays on mouse & human retinal organoid models
PhD defence
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Astrophysical plasma modeling of the hot Universe: Advances and challenges in high-resolution X-ray spectroscopy
PhD defence
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Regulatory Management Policies and a Universal Model for Public Policy Making, Legislative Drafting and Managing Stocks of Legislation
PhD defence
- Reaction driven ordering of the surface of a PtRh alloy model catalyst
- materials for CO2 and CO hydrogenation to higher alcohols: predictive modeling meets experiments
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Improving painkiller dosing in the clinic
Children, cardiac surgery patients or people who are obese. How can we improve the dosing of painkillers for these patients? Hospital pharmacist Sjoerd de Hoogd of the St. Antonius Hospital in Utrecht investigated this. He combined data from the hospital with the knowledge and expertise of the Leiden…
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Discoverer of the Year Paul Behrens: ‘We’re running out of time’
Earlier this year, the public voted environmental scientist Paul Behrens Discoverer of the Year 2018. Behrens is an interdisciplinary scientist who wants to understand our impact on the planet. ‘Unfortunately, we are not doing enough. Huge changes are underway and we’re running out of time to avoid…
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How China will reduce its carbon impact
Rong Yuang, PhD candidate from the Institute of Environmental Sciences investigated the impact of the renewable energy expansion on China’s carbon emission. On 17 May, she will defend her thesis. China is investing heavily in the development of low-carbon electricity sources, like nuclear, hydro-,…
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using population pharmacokinetic and physiology based pharmacokinetic modeling approaches
PhD defence
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Ensnaring tumours in their own web
Erik Danen is looking at how to inhibit tumours that do not respond well to medicine – and he is making some headway. The Professor of Cancer Drug Target Discovery studies the interaction between tumour cells and their surroundings. Inaugural lecture on Friday 10 May.
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Understanding metastasis: Science Groot grant for Erik Danen
A team led by Erik Danen from the Leiden Academic Centre for Drug Research has received a 3 million euros NWO Science Groot grant to unravel the first steps of metastasis. Danen will work together with biologists and theoretical and experimental physicists from Dutch Universities. ‘Understanding these…
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Computer Applications and Quantitative Methods in Archaeology Chapter Meeting
Conference
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Ada Lovelace Distinguished Lecture Series
Lecture
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Vici grant for Jeroen Codée: ‘I want to understand how sugars are formed’
Although sugars are widely used in biological and medical research, their synthesis is still badly understood. Jeroen Codée has received a Vici grant of 1.5 million euros for systematically studying the production of sugars. ‘I want to genuinely understand the reactions.’
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Building formal approaches for the study of spatial patterns in Galician moundscapes
Lecture
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Drugging the undruggable: NWO Open Competition grant for Alireza Mashaghi
Finding structure in disordered proteins and developing drugs for undruggable diseases: it might sound like mission impossible, but pharmacologist Alireza Mashaghi and his team are right on top of it. Their project was awarded by NWO through the Open Competition Domain Science -XS, a competition that…
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Remote Sensing in Ecology workshop
Conference, Workshop
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CANCELLED: Florence Nightingale Colloquium presents Max Welling
Lecture, Lunch included
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Florence Nightingale Colloquium presents Joaquin Vanschoren
Lecture
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Florence Nightingale Colloquium presents Eni Musta
Lecture
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Florence Nightingale Colloquium presents Max Welling
Lecture
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Florence Nightingale Colloquium presents Hein Putter
Lecture
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Florence Nightingale Colloquium presents Kristian Kersting
Lecture
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Florence Nightingale Colloquium presents Harrie Oosterhuis
Lecture
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Florence Nightingale Colloquium presents Tjeerd van Staa
Lecture
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Florence Nightingale Colloquium presents Ozan Öktem
Lecture
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Florence Nightingale Colloquium presents Peter Flach
Lecture
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Florence Nightingale Colloquium presents Francesca Ieva
Lecture
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Nightingale Colloquium presents Veronika Cheplygina
Lecture
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Nightingale Colloquium presents Cynthia Liem
Lecture
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Florence Nightingale Colloquium presents Johannes Schmidt-Hieber
Lecture, Lunch included
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Jan van Haaren brings Football Analysis to the Florence Nightingale Colloquium
Lecture, including drinks and nibbles at the FooBar
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Florence Nightingale Colloquium presents Cees Snoek
Lecture
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Florence Nightingale Colloquium presents Ronald Geskus
Lecture
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Florence Nightingale Colloquium presents Odette Scharenborg
Lecture, Lunch included
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Florence Nightingale Colloquium presents Nava Tintarev
Lecture
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Florence Nightingale Colloquium presents Javier Alonso Mora
Lecture
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Florence Nightingale Colloquium presents Peter Grünwald - webinar
Lecture