This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.

The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.

My ERC Starting Grant, funded with €1.5 million for 5 years as part of the Horizon 2020 research and innovation program, is focused on building the early warning system WARN-D to reliably forecast depression in young adults before it occurs. Why depression, and why prediction?

Analysis of drug adversity

Better links with the job market, diversity, quality of education, student well-being and free coffee. All these are issues that the student parties taking part in the University elections will be fighting for. The candidates are keen to tell you a bit about themselves. Between 9 May and 13 May you…

Students with learning problems experience difficulties in reading, writing, and content-area learning into and throughout their secondary-school years

What does a political party do in the wake of a disastrous electoral defeat? Martijn van Nijnanten researched this and discovered that parties turn to core values from the past. PhD defence on 12 September.

Establishing human induced pluripotent stem cell (iPSC) CRISPR-Cas9-based fluorescent reporter cell lines for NF-kB signalling. We will use this to enable studying the dynamic activation and downstream signalling of Toll-like receptor and cytokine signalling in iPSC-derived differentiated cells in a…

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

How can the transport of molecules in living cells help to target medicines at exactly the right place?

SLAVES TO THE SYSTEM: Locating Responsibility for Forced Expatriate Labour Practices by the Democratic People’s Republic of Korea (DPRK)

Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

Think tanks have proliferated in most Western democracies over the past three decades and are often considered to be increasingly important actors in public policy. Still, their precise contribution to public policy remains contested.

HomininSpace is an agent based modelling and simulation system in which fluctuating carrying capacity is the key attractor for hominin dispersal. A parameterized and spatially explicit reconstructed palaeo-environment models available energy in the form of secondary biomass using reconstructed climate…

On 14 November 2019, Luis Fiallos Pazmino defended his thesis 'Legal Perspectives on the Cross Border Operations of Unmanned Aircraft Systems'. The doctoral research was supervised by Prof. P.M.J. Mendes de Leon and Prof. E.C.P.D.C. De Brabandere.

A network combining 9 academic research groups and 4 collaborating industrial companies will train the next generation of PhD students and post-doctoral researchers, in developing and applying novel experimental and theoretical methods in the NMR spectroscopy of systems containing paramagnetic metals.…

Even though more than 4000 extra-solar planets are known today, only a small fraction of these has been captured in an image. To better understand the planet formation mechanisms in solar-like environments we started the Young Suns Exoplanet Survey (YSES).

What is Interaction between Legal Systems (ILS) and what does it entail as research profile area at Leiden Law School? More on this at the kick-off event of ILS 2.0. This will take place on Wednesday 26 October 15.00 – 17.00 in the Grotiuszaal (A051 KOG). The afternoon will be closed with drinks at…

Using artificial intelligence is more complicated for the government than for companies. Bram Klievink, Professor of Public Administration, aims to identify the problems and find solutions.

The Dutch National Student Orchestra will be going on tour again in February. Before that, they will have ten days of rehearsals. The level is high and taking part means a total immersion in music.

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

From descriptive to physiological models that can predict oral absorption and elimination of CYP3A substrates across the pediatric age range.

The potential of liposomal cancer vaccines

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

This paper describes two synthetic lipid models designed to replace human stratum corneum (SC) in studies of the impact of volatile organic chemicals on the molecular organization of the skin barrier lipids.

Homicide engenders broad moral concerns in society, and its aftermath can be understood as a barometer for criminal justice policy. Of all homicides committed, however, only some lead to arrest, to prosecution and ultimately to conviction in court.

Although both government and the public would like scientists to share their work with the widest possible audience, this does not always seem an easy route for scientists.

Now the election results are in, how should we interpret them? Time to call Associate Professor in Political Science Tom Louwerse.

Handbook of Signal Processing Systems is organized in four parts. The first part motivates representative applications that drive and apply state-of-the art methods for design and implementation of signal processing systems; the second part discusses architectures for implementing these applications;…

Lodewijk Petram, author of the book 'The World's First Stock Exchange', discussed the rise of the Amsterdam stock exchange in the 17th century in the ninth Hazelhoff Guest Lecture.

Promotor: Prof.dr. L.J. Slikkerveer

China is a one-party regime, yet elections are held for the local congresses. PhD candidate Wang Zhongyuan investigated how the Communist Party uses this democratic instrument to strengthen the authoritarian regime. PhD defence 31 January.

Anti-establishment parties with populist appeal have become part and parcel of the political landscape in many European countries. Some of these parties are more successful than others. PhD candidate Tomáš Cirhan studied the rapid rise of ANO, the party of Czech prime minister Andrej Babiš. He concludes…

Promotor: Prof.dr. M. Danhof

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

What is the origin of solar systems?

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.

PhD Defence

Governance and Global Affairs

The languages of the Mbam-et-Inoubou District of the Centre Region of Cameroon have a unique position in Bantu linguistics. Being in between

Cryptographer Max Fillinger developed new methods to analyse a group of algorithms called commitments schemes. These schemes are building blocks for cryptographic protocols, which enable multiple parties that do not trust each other to work together safely. His PhD Defence is on 19 March.

This doctoral thesis comprises four studies on the content and structure of physics teachers’ belief systems about teaching and learning physics in secondary education in the Netherlands.

In this programme, you will follow several core courses on topics such as political representation, elections, and political careers.

The elections for the Leiden University Student Council and Faculty Councils are coming up, starting on the 17th of May!

Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken