Promotor: Prof.dr. S.F. Portegies Zwart, Co-promotor: D.C. Heggie

A century ago, it was unclear whether the stars in the sky were clustered in groups, or widely spread in the universe.

Franx

Promotores: S.F. Portegies Zwart, E. M. Rossi

Promotor: K.H. Kuijken

Promotores: Prof.dr. M. Franx, Prof.dr. M. Kriek (Univ. of California at Berkeley)

When a star gets too close to a supermassive black hole, it is torn apart by strong tidal forces in a tidal disruption event (TDE).

Promotor: Prof.dr. K.H. Kuijken, Co-Promotor: Dr. H.Hoekstra

Promotor: Prof.dr. E. F. van Dishoeck, Co-promotor: A. N. Heays

One of the most important puzzles in modern astrophysics is the nature of dark matter.

Unfolding potential

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

In this thesis, dynamic testing principles were applied to examine young children's potential for learning. Our studies focused on the role of cognitive flexibility, to further increase our understanding of the cognitive processes involved in children's ability to learn from instruction and feedback,…

Circumstellar discs are the reservoirs of gas and dust that surround young stars and have the potential to become planetary systems.

An assessment approach that tailors to children’s instructional needs

Can dynamic testing provide us with insight in children’s potential for learning?

BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.

Knowledge and culture subproject 2:

The research of our group is centered around dynamical systems, functional analysis and their interplay.

The genomic DNA of every organism is organized and compacted in order to fit inside the cell. This is achieved by the joint action of numerous architectural proteins that aid in folding the genome. Genome folding is tightly interconnected with transcription, with genes in certain regions being silenced,…

Dynamic nuclear polarization with paramagnetic agents can enhance nuclear magnetic resonance signals by orders of magnitude. The mechanism of enhancement depends a.o. on the magnetic resonance properties of the agents used. Electron spin relaxation times at NMR relevant magnetic field/microwave frequencies,…

The research of this programme is centered around dynamical systems, functional analysis, and their interplay.

If gifted children are experts in using strategies, why do they experience problems with learning? Why do they underachieve?

Actin Polymerization and Membrane Physics in Living Cells: Analysis of cell spreading mechanisms

Promotor: W.Th.F. den Hollander

Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.

Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.

Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity.

Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez

Promotor: J.W. van Holten

Promotor: Huub de Groot, Co-promotor: Francesco Buda

What is the relationship between outcomes of dynamic testing and cognitive flexibility in young children?

Does a moving hybrid zone leave a genomic footprint?

John van Noort

Promotor: S.M. Verduyn Lunel

Promotor: H.J. van den Herik, B.R. Katzy, Co-promotor: K. Sailer

Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.

Cell adhesion signaling

Making a dynamic substance stock model in order to conduct scenario analyses and make forecasts.

Chemical reactions go hand-in-hand with an energy exchange with the environment in which they take place. Surfaces offer a variety of energy dissipation channels, constituted by the nuclear and electronic degrees of freedom of the atoms at the interface. Aiming at an improved future harvesting of energy,…

Promotor: S.M. Verduyn Lunel, Co-promotoren: M.F.E. de Jeu, S.D. Silvestrov

Promotores: Prof.dr. A.G.G.M. Tielens & Prof.dr. L. Kaper (UvA)

What is the optimal investment policy according to which a firm adapts its capacity in a competitive market?

In the early universe, the dynamics of the Higgs field can give rise to many interesting phenomena.

This research group is interested in the physics of living cells, especially their cytoskeleton dynamics under defined external stimuli.

Developing methodes to understand the evolution of patches in natural ecosystems