1258 search results for “negative polarity items” in the Public website
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Leticia Pablos Robles
Faculty of Humanities
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Operators in the lexicon. On the negative logic of natural language
Operators in the Lexicon opens with an old chestnut: why are there no natural single word lexicalizations for negations of the propositional operator and and the predicate calculus operator all: why neither *nand nor *nall?
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Dynamic Nuclear Polarization agents
Dynamic nuclear polarization with paramagnetic agents can enhance nuclear magnetic resonance signals by orders of magnitude. The mechanism of enhancement depends a.o. on the magnetic resonance properties of the agents used. Electron spin relaxation times at NMR relevant magnetic field/microwave frequencies,…
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Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.
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Remote sensing-based assessment of functional diversity for polar ecosystems
1: What is the relative importance of alfa and beta biodiversity in polar ecosystems, and how does intraspecific variation influence this? 2: How can we use remote sensing to determine functional biodiversity (within communities) in polar ecosystems? 3: Temporal and spatial scales of functional biodiversity:…
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Polar auxin transport: translating environmental signals into plant developmental responses
1. What is the exact role of PIN proteins in PAT? 2. How is PIN polarity established, and how is it modulated by AGC kinase-mediated phosphorylation? 3. What is the role of the AGC kinase, as modulators of PAT, in translating environmental signals, such as gravity, light or mechanical stress, to plant…
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Novel factors modulating AGC kinase signaling-controlled polar auxin transport
The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.
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Quantitative biology of polar auxin transport and plant development
The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…
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The Negative Effects of Bullying
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electrophoresis-mass spectrometry as a new approach for analyzing the polar metabolome
Metabolomicshas emerged as an important discipline to study molecular and cellular processes in living cells and organisms with the ultimate aim to obtain an answer to a given biological/clinical question.
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Antibiotic combination therapies against drug resistant Gram negative pathogens
Can effective synergists be identified to enhance the effect of antibiotics against Gram negative pathogens?
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Uncovering vulnerabilities in triple-negative breast cancer
Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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New study helps policymakers combat global warming with negative-emissions technology
Cutting down global emissions of greenhouse gases to combat global warming won’t do the trick alone: we also need negative-emissions technology that can capture carbon dioxide directly out of the air. In the prestigious journal Global Environmental Change, PhD candidate Oscar Rueda and colleagues shed…
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Trends in social assistance, minimum income benefits and income polarization in an international perspective
Social assistance and minimum income benefits are important instruments as a safeguard against low income and poverty. There have been major developments in minimum income benefits both in developed and developing countries over the last decades. Our study collects several empirical studies regarding…
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Transcutaneous vagus nerve stimulation reduces spontaneous but not induced negative thought intrusions in high worriers
Transcutaneous vagus nerve stimulation (tVNS) was tested in chronic worriers. tVNS may reduce spontaneously occurring negative thought intrusions. After a worry induction, there was no longer an effect of tVNS. tVNS did not affect physiological responding to worrying.
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Cognitive and behavioural emotion regulation after negative and traumatic life events
To study relationships between emotion regulation after negative and traumatic life events and psychopathology. Within this context, another goal is to develop and validate emotion regulation questionnaires.
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Are Citizens More Negative About Failing Service Delivery by Public Than Private Organizations?
Petra van der Bekerom, Joris van der Voet, and Johan Christensen, three assistant professors at Leiden University, conducted a large-scale survey experiment about whether citizens are more negative about failing service delivery than private organizations.
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Ton van der Wouden
Faculty of Humanities
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Negative concord in Turkish polar questions
Lecture
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Zeta-values of arithmetic schemes at negative integers and Weil-étale cohomology
This work is dedicated to interpreting in cohomological terms the special values of zeta functions of arithmetic schemes.
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Eefje de Goede
Science
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Single-electrolyte isotachophoresis: on-chip analyte focusing and separation
Promotor: Prof.dr. T. Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto
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Remko Offringa
Science
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Negative consequences of antiterrorism policy in Europe
‘It's right and proper that we have policies to prevent terrorism,' says Francesco Ragazzi, university lecturer in International Relations at Leiden's Institute of Political Science. 'But the way the policies are designed and implemented can have unintended consequences. For example, when teachers are…
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Bias or reality?
Negative perceptions of ambiguous social cues, social performance and physical arousal in socially anxious youth
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Henk Kelderman
Faculteit der Sociale Wetenschappen
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Nanofluidic tools for bioanalysis: the large advantages of the nano-scale
Promotor: Prof.dr. T. Hankemeier, Prof.dr. J.C.T. Eijkel (Twente University)
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Arabidopsis AGC3 kinases and PIN plasma membrane abundance
The plant hormone auxin plays a central role in the growth and development of plants. Auxin acts in a concentration dependent manner and polar cell-to-cell transport of this hormone determines its distribution in the tissues of plants. This polar auxin transport is mediated by several families of auxin…
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Novel pharmacometric techniques to quantify the pharmacodynamics of analgesics
The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics.
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Anne Miers
Faculteit der Sociale Wetenschappen
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Fire use in human evolution: A genetic approach
Are traces of fire use detectable in ancient hominin genomes?
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Optical properties of DNA-hosted silver clusters
Promotor: D. Bouwmeester, Co-promotor: D. Kraft
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Representations of the Overseas World in the De Bry Collection of Voyages, 1590-1634
This book reveals how one publishing firm's editorial strategy helped to legitimate European colonialism in the early modern era.
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Kamaleddin Hajmohammadebrahimtehrani
Science
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Publications
A selection of recent publications from the Plant BioDynamics Laboratory.
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Yes/no question-marking in Italian dialects - A typological, theoretical and experimental approach
This dissertation provides an account of polar questions in Italian dialects from a typological, theoretical and empirical perspective.
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Auxin
Mathematical and computational analysis of the dynamics of polar transport of the plant hormone auxin.
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Sodium ion binding pocket mutations and adenosine A2A receptor function
Source: Mol Pharmacol, Volume 87, Issue 2, pp. 305-13 (2015)
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Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination
CONCLUSION: This study demonstrates that human macrophages can be induced to exert direct anti-tumor activity against osteosarcoma cells. Our observation that the induction of macrophage anti-tumor activity by L-MTP-PE required IFN-gamma may be of relevance for the optimization of L-MTP-PE therapy in…
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Value Congruence in a Multinational Corporation
On 29 June 2017, Doris Dull-Zessner defended her PhD dissertation “Value Congruence in a Multinational Corporation”. The supervisors are Professor J.A.A. Adriaanse and Professor J.I. van der Rest.
- Martina Huber Lab (EPR Group)
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Cavity quantum electrodynamics with quantum dots in microcavities
Promotor: Prof.dr. D. Bouwmeester, Co-promotor: M.P. van Exter
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The development and prevention of social anxiety in youth
What are the developmental pathways to social anxiety (disorder), the causal processes and maintaining factors? How do these factors interact in the development of social anxiety disorder? How can this knowledge be used to design and implement effective preventive intervention programs for youth?
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Research
PBDL favors multidisciplinary research. Depending on the problems under investigation, PBDL establishes collaborations between experts from for example molecular genetics, molecular and electro cell physiology, biochemistry, organic chemistry, analytical mathematics, mathematical statistics and computational…
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Small-molecule inhibitors of bacterial metallo-β-lactamases
The main focus of the thesis is the discovery and development of novel inhibitors of bacterial metallo-β-lactamases (MBLs).
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Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
PhD Defence
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helminths: from molecular diagnostics to mechanisms behind immune polarization
PhD Defence
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Spectropolarimetry for planetary exploration
Promotor: Prof.dr. C.U. Keller, Co-promotor: Dr. ir. Frans Snik
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About Heritage Quest
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