Operators in the Lexicon opens with an old chestnut: why are there no natural single word lexicalizations for negations of the propositional operator and and the predicate calculus operator all: why neither *nand nor *nall?

Dynamic nuclear polarization with paramagnetic agents can enhance nuclear magnetic resonance signals by orders of magnitude. The mechanism of enhancement depends a.o. on the magnetic resonance properties of the agents used. Electron spin relaxation times at NMR relevant magnetic field/microwave frequencies,…

Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.

1: What is the relative importance of alfa and beta biodiversity in polar ecosystems, and how does intraspecific variation influence this? 2: How can we use remote sensing to determine functional biodiversity (within communities) in polar ecosystems? 3: Temporal and spatial scales of functional biodiversity:…

The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…

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Can effective synergists be identified to enhance the effect of antibiotics against Gram negative pathogens?

Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.

Transcutaneous vagus nerve stimulation (tVNS) was tested in chronic worriers. tVNS may reduce spontaneously occurring negative thought intrusions. After a worry induction, there was no longer an effect of tVNS. tVNS did not affect physiological responding to worrying.

Extending our current arsenal of antibiotics is key to staying ahead in the arms race between humans and resistant bacteria.

Petra van der Bekerom, Joris van der Voet, and Johan Christensen, three assistant professors at Leiden University, conducted a large-scale survey experiment about whether citizens are more negative about failing service delivery than private organizations.

As a bachelor student of Bio-Pharmaceutical Sciences, Femke Vlaswinkel wrote a research proposal she was allowed to carry out in her master’s BPS. Femke subsequently graduated with honors. Her research was published in the journal Scientific Reports, she won an award from the Dutch Pharmacy Society…

People who have taken antibiotics in the past three months pay more attention to negative facial expressions, according to research by postdoc Katerina Johnson and assistant professor Laura Steenbergen. This may explain how antibiotics increase the risk of developing depression.

Negative perceptions of ambiguous social cues, social performance and physical arousal in socially anxious youth

The asylum seekers’ centres in Hengelo, Almelo and Schalkhaar caused little or no nuisance in recent years. There have been hardly any incidents, according to information received by Dutch regional TV channel RTV Oost. However, Maarten Offinga, Mayor of Hardenberg, sounded the alarm with the state secretary…

Promotor: Prof.dr. T. Hankemeier, Prof.dr. J.C.T. Eijkel (Twente University)

This study looks at population response to government containment strategies during initial stages of the COVID-19 pandemic in four high-trust Northern European countries–Denmark, Germany, the Netherlands, and Sweden–with special emphasis on expressions of governmental trust.

The plant hormone auxin plays a central role in the growth and development of plants. Auxin acts in a concentration dependent manner and polar cell-to-cell transport of this hormone determines its distribution in the tissues of plants. This polar auxin transport is mediated by several families of auxin…

The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics.

Promotor: D. Bouwmeester, Co-promotor: D. Kraft

CONCLUSION: This study demonstrates that human macrophages can be induced to exert direct anti-tumor activity against osteosarcoma cells. Our observation that the induction of macrophage anti-tumor activity by L-MTP-PE required IFN-gamma may be of relevance for the optimization of L-MTP-PE therapy in…

PhD defence

Source: Mol Pharmacol, Volume 87, Issue 2, pp. 305-13 (2015)

A selection of recent publications from the Plant BioDynamics Laboratory.

On 29 June 2017, Doris Dull-Zessner defended her PhD dissertation “Value Congruence in a Multinational Corporation”. The supervisors are Professor J.A.A. Adriaanse and Professor J.I. van der Rest.

Mathematical and computational analysis of the dynamics of polar transport of the plant hormone auxin.

Study why and how, in countries around the world, people mobilize around ethnic, racial, religious and social identities, and explore the role of political institutions in mitigating conflicts that arise from such mobilization.

Promotor: Prof.dr. D. Bouwmeester, Co-promotor: M.P. van Exter

PhD defence

Does democracy still work? How does political representation function in times of fragmentation, populism and polarization? You will study the challenges that established and new democracies face.

In this work, we investigate the minute circular dichroism effects of single nanoparticles.To this aim, we apply photothermal imaging with a polarization-modulated heating beam.

Integrins play an essential role in multicellular life by connecting cells to the extracellular matrix.

Promotor: Prof.dr. C.U. Keller, Co-promotor: Dr. ir. Frans Snik

Heritage Quest has featured in several media. Read and watch the items made by others about the project.

Social relationships of students are important. Especially for students with problem behavior. How can a teacher support students in their social relationships via their own interactions with students? A lot, as is shown by a meta-analyses of Hinke Endedijk. She assessed almost 300 studies about teacher-student…

How do different emotional expressions influence the behavior of other people in negotiations?

The mission of the Plant Science research programme is to contribute to the sustainable production of high quality crops, flowers and high-value bio-based products. This is realised by generating fundamental knowledge of basic biological processes related to development of plants and their interaction…

This thesis is a sample-based typological study of formal and semantic patterns in terms for a selection of referring (

CERQ is a questionnaire measuring cognitive coping strategies developed by Dr. Nadia Garnefski and Dr. Vivian Kraaij.

Jens Iverson, Assistant Professor of International Law and a Researcher in the Jus Post Bellum Project, defended his Ph.D. dissertation on 21 September 2017.

Sanne Kellij and colleagues systematically reviewed 142 articles, examining evidence for three hypotheses on the relation between victimization and social information processing.

People who have taken antibiotics in the past three months pay more attention to negative facial expressions, according to research by postdoc Katerina Johnson and assistant professor Laura Steenbergen. This may explain how antibiotics increase the risk of developing depression.

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

On Tuesday 26th September Jessica Hill defended her thesis ‘On the road to adulthood. Delinquency and desistance in Dutch emerging adults’. The supervisor is Professor Arjan Blokland.

The objective of this project is the development of a new psychometric model, called the Generalized Squared Distance Logistic Model (GSDLM). This model is an evolution of older psychometric approaches (such as PARELLA, GHCM, and GGUM) and the Gaussian Ordination Models (GOMs) used in environmental…

Statements made by Caroline van der Plas about nitrogen emissions and European law are incorrect: Armin Cuvyers on Dutch radio EenVandaag programme’s item ‘fact or fiction’.

PhD defence

Former PhD, Bachelor and Master students of the Van Exter Lab

Promotores: P. Stevenhagen, A. Enge Co-Promotor: T.C. Streng