Source: Mol Pharmacol, Volume 87, Issue 2, pp. 305-13 (2015)

Supervisor: Gerard van Westen

‘I would never want to be treated by a computer,’ says Boudewijn Lelieveldt, Head of Radiology at the Laboratory for Clinical and Experimental Image Processing and Medical Delta professor in the Bioinformatics group at Delft University of Technology. No matter how intelligent a system, we have to continue…

Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan

This thesis describes the use of the evolutionary approach in the study of language change, aiming to provide a better insight in the mechanisms that play a role in language change and to validate this approach in the field of language change.

A modeling approach with applications to the Bau de l'Aubesier (Southeastern France)

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In what way can the qualities of an existing context be used as guiding and enriching principles rather than limiting factors in the process of spatial transformation?

Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp

Modern society is connected through electronic and mobile devices, which we call the Internet of Things (IoT).

Mathematical models of software systems enable characterizations, abstractions, simulations, and analysis of complex software during its development.

Education and Organisation Development

Computer applications and quantitative methods in archaeology CAA95.

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

This thesis covers several aspects of quantum algorithms for near-term quantum computers and its applications to quantum chemistry and material science.

The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine. The available expertise extends…

Gold nanorods are biocompatible nanoparticles that present an excellent two-photon signal that can be used to get high spatial resolution inside living cells. Gold nanorods are photostable and therefore can be followed inside cells for long time, with possible applications as trackers in live cells.

The group Theoretical Physics of Life Processes, led by Helmut Schiessel, focuses on the physics of chromatin, the DNA-protein complex that fills the nuclei of eukaryotic cells.

Lecture

The discovery that eleven asteroids might collide with our Earth has become world news. The research of three Leiden astronomers has appeared on more than 190 news sites worldwide, from America to China. They developed and trained an artificial neural network for this discovery.

Lecture

PhD defence

PhD defence

PhD defence

PhD defence

Predictive maintenance (PdM) is a maintenance policy that uses the past, current, and prognosticated health condition of an asset to predict when timely maintenance should occur.

Promotor: M. de Jong, Co-Promotor: Samtleben

Leiden Journal of Pottery Studies 22, 2006

Bicarbonate buffer is largely found in nature due to its ability to regulate pH variations around neutral values. As the pH changes, so does the speciation of the buffer.

Vast, often populated, areas in dryland ecosystems face the dangers of desertification.

Reactions and reaction times in cognitive tasks.

This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.

One of the effects of climate change is the phenomenon of desertification, a process that occurs in semi-arid and arid areas and causes land degradation as well as vegetation loss. Due to the lack of resources, vegetation self-organizes to sustain itself by forming large-scale spatial patterns.

The master's specialisation Astronomy Research at Leiden University students focus on astronomical data analysis using models and large-scale simulation, combining the fields of Astronomy, Physics, Mathematics and Computer Science.

A century ago, it was unclear whether the stars in the sky were clustered in groups, or widely spread in the universe.

Promotor: M.L. van Hecke

We have studied the impact of particle shape anisotropy, multivalent interactions and flexibility on systems of micron-sized colloidal particles.

Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.

Making systems biology modelling a central pillar of research in biology

A plasma is an ionized gas with very low electrical resistivity. As such, magnetic field lines are 'frozen in' and move with the fluid. Magnetic field lines that are linked, knotted and tangled, cannot be undone by the fluid motions.

Promotor: M.L. van Hecke, Co-Promotor: B.P. Tighe

Moot Court: An academic skills training course

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

Stars like the sun are born in large molecular clouds existing from gas and dust. During the formation process, the chemical composition of the material can be altered drastically by the changing physical conditions.

The Plant BioDynamics Lab (PBDL) is a laboratory dedicated to experiments designed to develop and validate quantitative mathematical models of dynamical processes in biology. The principal objective of developing these models is to make quantitative predictions about these processes.

Three major cosmology-focused missions are planned for the next decade: the Euclid space telescope, the Vera C. Rubin Observatory in Chile, and the Nancy Grace Roman Space Telescope.

Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.

Every year, the Netherlands Red Cross and Belgian Red Cross-Flanders organise the Frits Kalshoven IHL Competition. This competition aims to provide students with an opportunity to practically engage with IHL, the rules that govern the conduct of war, by attending expert lectures and workshops, engaging…