This handbook provides a resource for those already familiar with some kinds of micro-particles who wish to learn more about others, or for those just starting out in the study of microremains who wish to have a broad understanding about microscopic archaeology.

We have studied the impact of particle shape anisotropy, multivalent interactions and flexibility on systems of micron-sized colloidal particles.

Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

A team of students from Leiden and Groningen took the second prize at the European final of the BISC-E sustainability competition. Last June, the team had already won the Dutch finals. The students came up with ‘Suckerspheres’, a natural alternative to the plastic micro-particles that are still frequently…

Poly(lactic-co-glycolic acid) (PLGA) particles have been extensively studied as biodegradable delivery system to improve the potency and safety of protein-based vaccines. In this study we analyzed how the size of PLGA particles, and hence their ability to be engulfed by dendritic cells (DC), affects…

Promotores: W. Jiskoot, F. Ossendorp

The lipid membrane is a basic structural component of all living cells. Embedded in this nanometer-thin barrier, membrane proteins shape the membrane and at the same time respond to the shape of the membrane.

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

The purpose of this study was to investigate the formation and growth kinetics of complexes between proteins and oppositely charged polyelectrolytes.

Atherosclerosis is a chronic inflammatory disease affecting millions of people world-wide.

Bioarchaeology covers the study of all biological remains from archaeological sites.

In Quantum mechanics, particles can be in multiple positions simultaneously. Yet, when a measurement is made, the particle is found only in one place. Technology has come to a point where we may design experiments that will tell us how.

The editors of Biophysical Journal have selected a publication from Daniela Kraft’s group as the Paper of the Year 2017. The award recognizes an outstanding contribution by a young investigator.

The image of the Leiden microboat traveled all over the world, from the BBC up to Arab shipping blogs. But Daniela Kraft's research group has quite a few more different 3D printed microswimmers up their sleeves. Kraft receives a Vidi research grant for research into these variously shaped active par…

A couple of years ago, Dr Amanda Henry noted that she was unable to determine all microremains in her archaeological samples. Herself an expert on starches, she had trouble recognising other microparticles. Seeing the importance of interdisciplinarity, she organised a conference on microremains. This…

Leiden archaeologists investigate how people in the past impacted their environment. Together with scientists, environmental scientists, and humanities experts, they use this information to draw conclusions about the present – and show what we can learn from it for the future.

Daniela Kraft will be awarded the NWO Athena Prize 2019 in a ceremony at the CHAINS Chemistry Conference on 10 December. The prize recognizes excellent female chemists who carry out outstanding scientific research and act as role models for their fellow researchers. Kraft will receive the Athena Prize…

Four scientists from Leiden University have each been awarded a Starting Grant by the European Research Council (ERC). This grant, worth up to two million euros, gives researchers the opportunity to head up a research team for five years.

Nanoplastics influence the behaviour of larval zebrafish, says new research by the Institute of Biology Leiden (IBL) and the Institute of Environmental Sciences (CML). The researchers observed that a certain type of nanoparticles leads to stress reactions in the sugar balance, resulting in hyperactivity…

Playing with tiny building blocks might sound like child’s play, but Vera Meester knows better. On June 7 she will defend her thesis on colloids: micro particles with which you can form larger structures. Meester developed a method to make unusable structures usable.

A team of researchers has managed to recreate the most natural skin cream in existence. Using the DUBBLE beamline (Dutch Belgian Beamline) at the European Synchrotron Radiation produced on the basis of the information identified, has the same properties as vernix caseosa. This cream may have a therapeutic…

Dennis Claessen has been appointed professor of Molecular Microbiology at the Institute of Biology Leiden. With his teaching and research on the cell wall, the professor wants to establish applications in the industry and the medical sector.

The Joan Van der Waals colloquium is an ongoing bi-weekly lecture series.