7 search results for “lipopeptides” in the Public website

• VOILA (Validation of Innovative Lipopeptide Antibiotics) Research project

  Examining the therapeutic potential of new semisynthetic lipopeptide antibiotics

• In Pursuit of Next-Generation Lipopeptide Antibiotics Research project

  Can new variants of daptomycin and the polymyxins be found?

• In vitro and in vivo delivery of functionalized nanoparticles via coiled-coil interactions Research output

  Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn

• Coiled-coils on lipid membranes: a new perspective on membrane fusion Research output

  Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

• Giant unilamellar vesicles: An efficient membrane biophysical tool and its application in drug delivery studies Research output

  Promotor: A. Kros

• Membrane Fusion Mediated Intracellular Delivery of Lipid Bilayer Coated Mesoporous Silica Nanoparticles Research output

  Alexander Kros and co-workers describe how mesoporous silica nanoparticles (MSNs) are delivered into cells via membrane fusion thereby omitting endocytosis pathways. Fusion is induced by a pair of complementary coiled-coil lipopeptides inserted into the membrane of cells and in the bilayer of lipid-coated…

• Antibiotic combination therapies against drug resistant Gram negative pathogens Research project

  Can effective synergists be identified to enhance the effect of antibiotics against Gram negative pathogens?