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Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…

Research at the MCBIM group is comprised of the following research themes:

Can light-activatable ruthenium compounds be used as a more selective anticancer treatment?

How does the photoregulation mechanism work in detail?

Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…

The Aging and Immunity group is led by Dr. Amanda Foks. In this group we aim to investigate how aged immune cells contribute to atherosclerosis and identify novel therapeutic targets and strategies to extend health span and inhibit cardiovascular disease.

How do forensic scientists deal with complex DNA-evidence found at crime scenes? Giulia Cereda developed new statistical models to analyse them. PhD defense 12 January.

Researchers from the Leiden Institute of Chemistry show proof of principle that live-cell structural changes and metabolic processes can be followed in real time with NMR spectroscopy. They performed their study on photosynthetic green algae that are metabolically flexible and can sustain energy generation…

- How to deconvolute metabolic mixture of precursors and products by biontransformation? - How to optimize the reaction conditions to produce bioactive compounds in biotransformation? - What is the effect of co-treating fungi or bacteria for biotransformations?

The editors of Biophysical Journal have selected a publication from Daniela Kraft’s group as the Paper of the Year 2017. The award recognizes an outstanding contribution by a young investigator.

Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…

Volume 4 and 5 of the Leiden series 'Dutch Sources on South Asia' are now available, written by Markus Vink (vol.4) and Carolien Stolte (vol.5).

A couple of years ago, theoretical physicist Carlo Beenakker tracked down the Majorana particles and inspired Leo Kouwenhoven from TU Delft to try to create them in a superconducting nano-structure. He succeeded in doing so in 2012, and the news made headlines around the world. But a lot of work still…

How and to what extent the historic house (re-)constructs identity through image-making in China.

Improving environmental risk assessment of pesticides in surface waters

In the logic and aesthetics of a republican baroque the existing world is the result of a moment in which for a split second two or more realities are equally real and after which only a singular one becomes actualized.

The project will clarify that in the search for these new means the treatise On the sublime of ps.-Longinus played a crucial role. However, the project will also place the theatre performances in a broader social and political perspective. These public events and the theatre performances suggest that…

Promotor: H.J.M. de Groot

The ambition to have flexible learning pathways is about creating possibilities to improve the content and form of students’ learning process, and to link learning to students’ needs. Students who have access to a flexible range of learning pathways can align their university career with their own personal…

Metabolomicshas emerged as an important discipline to study molecular and cellular processes in living cells and organisms with the ultimate aim to obtain an answer to a given biological/clinical question.

With a pioneering project like the quantum computer, it’s a good idea not to place all your bets on a single horse. In Leiden’s Quantum Optics research group, instead of working on a Majorana-based qubit, people are working on a qubit based on an ‘artificial atom’. If that becomes the basis of the quantum…

A team of researchers has managed to recreate the most natural skin cream in existence. Using the DUBBLE beamline (Dutch Belgian Beamline) at the European Synchrotron Radiation produced on the basis of the information identified, has the same properties as vernix caseosa. This cream may have a therapeutic…

Cardiovascular diseases are the leading cause of death across the world. Professor Johan Kuiper of Leiden University carries out research to develop a vaccine for arteriosclerosis, which is the main cause of cardiovascular diseases. With the aid of a European research grant of six million euros he is…

A full overview of MCBIM PhD theses.

The research in the Biosyn group is focused on the design, synthesis and function of the four major types of biomolecules: nucleic acids, carbohydrates, peptides and lipids and hybrid structures thereof. These biomolecules and their derivatives are used in drug discovery and chemical biology, to develop…

The goal of hit discovery is to identify suitable chemical starting points to modulate a drug target. A hit can be, a.o., a small molecule, a protein or mRNA. Hit identification is performed via rational design, genome mining, (targeted) library screening, or in silico approaches.

LACDR, the Leiden Institute for Drug Research, developed better tolerated excipients to prevent adverse effects related to the surface of nanosized drugs such as vaccines. LADCR professor of Biopharmacy Matthias Barz and Polypeptide Therapeutic Solutions (PTS) are collaborating to develop processes…

Vera Meester has won the annual Physics Image Award 2016, with her photo of 'smiling' colloids. The Volkskrant published the picture as Image of the Week.

Aqueous solutions of proteins and carbohydrates separate into two parts with an extremely ‘soft’ boundary surface. The surface tension between these two parts can be manipulated, for example by adjusting the pH balance. This can be used to develop emulsions of a water-based solution in another aqueous…

Jo-Anne Verschoor wins the Unilever Research Prize 2020. The master's student in Biology developed a method to test whether bacteria are capable of degrading plastic. Verschoor: 'Using specific enzymes from these bacteria, we may be able to efficiently recycle plastic in the future.

The immune system plays an important role in the development of atherosclerosis, the underlying cause of cardiovascular diseases. Thomas van der Heijden has discovered that immunosuppressants may play a preventative role. PhD defence 19 December.

The master’s programme Industrial Ecology (IE) started in 2004 with 12 students and has increased until 90 students from 20 different countries this year.

The surface and the edges of graphene are expected to provide higher sensitivity and specificity in detecting and characterizing single molecules. However fundamental physical limits exist in reaching an ultimate precision in detecting the dynamics of chemical and biological systems. The research in…

What do a novel anti-ageing ingredient for cosmetics and a new type of chicken feed have in common? They were both produced using a new solvent developed by Leiden biologists in 2011. The medium is neither solid nor liquid, and the industry is now starting to see it’s many possibilities.

Lecture

An overview of the research at the Cancer Dug Target Discovery group.

The main research theme in the group of Dennis Hetterscheid is to understand and mimic bioinorganic multi-electron processes that are relevant to our future energy infrastructure. Reduction of protons generates hydrogen that can be used as a chemical fuel. Alternatively to gaseous hydrogen, the reduction…

Leiden University Library and related museum holdings in Leiden contain a body of materials showing the unique role of Dutch-Japanese trade relations as a node in the history of global flows of knowledge, materials and culture during the early modern period.

Science

The nanoscale structure of a catalyst under reaction conditions determines its activity, selectivity, and stability. For the production of sustainable energy and materials, new catalysts are needed. By understanding the structure-activity relationships of catalysts under reaction conditions, insight…

Quantum computers deserve their own quantum internet. This is a network that dispatches information not in the form of bits - ones and zeros - but rather as qubits, just like in the quantum computer itself. In the view of Dirk Bouwmeester, a professor in Leiden’s Quantum Matter & Optics research group,…

Science, Leiden Institute of Physics (LION)

This summer the department of Labour Law at Leiden University will start a new tradition of an annual summer school addressing current issues in labour law from an international, transnational and European point of view. With a mixture of lectures, seminars and a field trip, topics will be explored…

The Hague Journal of Diplomacy is delighted to announce it will be starting its own podcast series! The series will be aimed at bringing the themes of the journal’s research off the page, and onto the discussion table. Each episode will feature a guest who will share their insights and personal experience…

Professor of Ultrastructural Biology Ariane Briegel has received a grant in the NWO Open Competition Domain Science in the XS category. This grant emphatically encourages curiosity-driven and bold research with a maximum of 50,000 euros.

The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.

The research of the Van Eck Group focusses on 3 interconnected research lines: 1) Identification and therapeutic targeting of key pathways/regulators in macrophages essential for prevention of atherosclerotic lesion development or stimulation of regression of existing lesions, 2) Atherosclerosis as…

Selected publications of the Cardiovascular and Metabolic Therapeutics group.