Kidney transplantation used to be an experimental risky procedure, but is now routinely performed by many countries worldwide.

Searching for ways to delay the need for a transplant and trying to build kidneys to order.

Treatment with special stem cells seems to be a good option for suppressing the immune system in organ transplants. Researchers are trying to learn from processes that take place in the human body during pregnancy.

Stem cells can be differentiated into insulin-producing cells.

PhD Defence

In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

The LUMC is the first medical institution in the world to offer a Massive Open Online Course (MOOC) on clinical kidney and pancreas transplantation.

Everyone wherever they are in the world can follow free online academic courses offered by Leiden University.

PhD Defence

PhD Defence

Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius

Kidney failure is a serious issue because kidneys cannot regenerate themselves after injury. A possible solution consists of artificially growing healthy kidney tissue. To achieve that, scientists first need to understand kidney development during the earliest stages, in the fetus. Leiden researchers…

Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…

PhD Defence

What dose of medicine do you give a child? That depends to a large extent on how quickly their kidneys remove the drug from the blood. For ethical reasons it is impossible to measure this directly in little patients. PhD candidate Sinziana Cristea combined different types of modelling and lots of data…

PhD Defence

PhD Defence

Our immune system protects us against disease, but every now and then, something goes wrong: an enemy invades our bodies or our immune system attacks our own cells and we become ill. Doctors and researchers at the Leiden University Medical Center (LUMC) want to be able to manipulate the immune system…

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

With our research and teaching, we help make the world a better place. We join in the academic and public debate, and seek answers to economic and social issues – not just at the local and regional level but at the global one too.

Nineteen new Leiden University MOOCs have started this January. Anyone can take part in these online courses varying from combatting terrorism to kidney transplantation.

Leiden University now offers almost 20 Massive Online Open Courses (MOOCs). The enthusiasm displayed by participants makes it rewarding to develop and teach such courses, say MOOC lecturers Marlies Reinders and Edwin Bakker. But that is not all, ‘You bring together a global community.’

Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.

Exhibition

PhD Defence

We will study how inoculation of former arable land with soil (including the microbiome, soil fauna and seeds/rhizomes of ground flora) from old forests along with planting targeted tree species mixtures will improve productivity and more rapidly restore forest-adapted communities and ulttimately result…

PhD Defence

Physicians and researchers of the Leiden University Medical Center (LUMC) and Leiden University are working on therapies for restoring damaged organs such as hearts and kidneys. They are even trying to construct tailor-made organs. Read more on this topic in the new science dossier on Vascular and Regenerative…

PhD Defence

PhD Defence

The kidneys play a major role in the elimination of drugs. In children, the exact age-related physiological changes underlying kidney function remain largely unknown.

The LUMC has a longstanding tradition researching the role of the immune system in infectious diseases, transplantation and auto-immune diseases.

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.

PhD Defence

PhD Defence

PhD Defence

In what way did Hellenistic legal institutions concerning secured credit influence Roman law?

PhD Defence

Organ transplantation is often subject to ethical, economic and political discussions. In the Honours Class Organ Transplantation, students take part in these discussions to get a better understanding of the many different views on transplantation.

What is a good data protection law? How does a good data protection law evolve? Is European data protection law a good one? And whether the European data protection applicable to China?

The United Nations’ fourth Sustainable Development Goal (SDG) aims to “ensure inclusive and equitable quality education and promote lifelong learning opportunities for all”. The Centre for Innovation at Leiden University feels the responsibility to tackle this need. Our mission is to drive innovation…

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments. We apply our technology and methods to find biomarkers for key disease pathways and toxicity in clinical studies and in…

Promotor: Prof.dr. B. van de Water, Co-promotor: L.S. Price

PhD Defence