In this Thesis, novel charge induction mechanisms of ionic liquids are treated, tested and experimented on complex oxides, in particular cuprates.

This thesis explores interfacial conductance and electric field-effects in LaAlO3/SrTiO3 heterostructures.

Ancient Greek was spoken in a large number of different dialects. Although we do not find direct evidence for syllabic liquids in any of our sources, comparative evidence shows that these sounds must have been present in Proto-Greek, and that they were retained until comparatively recently in the prehistory…

PhD Defence

The present study explores the role of water in the ancient Roman city of Ostia.In antiquity, Ostia was situated at the intersection of the Tiber River and the Mediterranean Sea, and acted as one of the harbour cities of Rome for several centuries.This study investigates how water was acquired, used,…

Water, Urbanism, and Sustainability in Roman Ostia

Subproject of

We study the interplay of topology and geometry with chirality for several passive and active systems, employing both analytical and numerical methods.

The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.

With the energy transition toward a renewable energy supply and a CO2-neutral economy, electrification of the energy system is rising in importance, which leads to the challenge of long-term storage of renewable electricity.

The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.

Ionic liquids are important in scientific research because they can apply a lot of charge over a surface. Leiden physicists have now found that the charging process of ionic liquids purely depends on opposite charges attracting each other. Chemical reactions are sometimes involved, but not essential.…

LCD screens use liquid crystals which have a high degree of order, even though they form a fluid. A new theory maps out the interplay between order, temperature and symmetry. Publication in Physical Review X.

111 years ago, Heike Kamerlingh Onnis liquified helium for the first time, a tour the force that netted him the Nobel prize. It took a laboratory of a size rarely seen. Now, ultracold helium has become a commodity for physics research. In Wolfgang Löffler's lab, it is ready at hand thanks to a coffee…

Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease progression and treatment response. A Systems Medicine approach, based on computational…

Promotor: J. Zaanen

We focus on natural products research, traditional medicine, ethnobotany and phytochemistry.

Graphene nanoribbons (GNRs) are used as a current carrying substrate in investigation of current-induced forces in a low-temperature STM (chapter 2).

This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.

After 2 years of planning, designing, testing and adjusting, the brand-new low-vibration physics lab at the new Gorlaeus Building of the Science Campus is working like a charm and ready to make its mark in the world of science. Also, the renewed facility for the production of liquid helium is all do…

In multi/many-core System-on-Chips (SoCs), the performance is almost linearly scaling with the number of processing elements.

Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: Prof. dr. V. Vitelli

Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken

- Which metabolites could be components of NADES? - How can we prove the presence of NADES in nature? - What are the roles of NADES in nature? - How to apply NADES in life sciences?

The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.

This project aims to excavate and date the setting of the east gate of the Roman fortress of Udhruḥ. This will be compared with other Diocletianic military installations from the region. We also hope to retrieve another gate inscription which can shed light on the function and political embedding of…

Instead of the finger scanner we now use a QR code based access system for the USC location.

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

The Cryogenics Department has a liquid helium production unit and an automatic liquid nitrogen filling plant.

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

Publication in Proceedings of the National Academy of Sciences.

What are the mysteries behind soft condensed matter?

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

The research aim of the Catalysis and Surface Chemistry group headed by Prof. Marc Koper is to probe and understand chemical reactions on well-defined, mostly single crystalline, surfaces at the molecular level.

In the near future oral polio vaccine (OPV) will be replaced by inactivated polio vaccine (IPV) as part of the eradication program of polio. For that reason, there is a need for substantial amount of safe and more affordable IPV for low-income countries. Bioneedles, which are biodegradable mini-implants,…

Promotor: Prof.dr. T. Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto

This thesis describes the design, characterization and application of dextran based crosslinked network.

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

PhD Defence

PhD Defence

PhD Defence

This editorial to RHCPP discusses how COVID-19 can be seen as a 'creeping crisis' according to the authors of its lead article (Boin et al, 2020) and how resilience may depend on the real heroes behind the scenes of response to disaster and adversity.

Lecture

Can we develop a generic method for Quan/Qual analysis of small molecule drugs, their metabolites and endogenous metabolites in (pre-)clinical samples?

Promotor: Prof.dr. M.L. van Hecke

Promotor: M.A.G.J. Orrit

The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.