536 search results for “innate immunity” in the Public website
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Implications of memory CD8 T cell quality for protective immunity
PhD Defence
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The interplay between lipids and the immune system in atherosclerosis
PhD Defence
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Modulation of the immune system for treatment of atherosclerosis
PhD Defence
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Visual arts and geometry
Knowledge and culture subproject 3:
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Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…
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Scientists find strong evidence that wasting syndrome is the same for all organisms
An interdisciplinary team of Leiden researchers has discovered that wasting syndrome, a severe byproduct of tuberculosis, is the same for all humans and animals studied. The discovery offers new opportunities to investigate the still insufficiently understood condition. The scientists also developed…
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A summer abroad, but then virtually
For many students, a summer school abroad is a fun and useful way to spend the summer. This year, because of the travel restrictions, many summer schools were held online. There was no less interest from students though. What is it like to study in a different country, but digitally? Or to travel abroad…
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Research
At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.
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Two NWO ECHO grants for Leiden Chemistry
Two excellent young chemists, Jeroen Codée and Sander van Kasteren, have received an ECHO grant for €260,000 from the Netherlands Organisation for Scientific Research (NWO). This funding will allow them to begin their research projects.
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Replacing the needle and syringe for vaccine administration
Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra
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New generation alum based vaccine adjuvants
Aluminium-based adjuvants, such as aluminium hydroxide and aluminium phosphate, are well-known for their immune-stimulating properties.
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BioTherapeutics
Research in the BioTherapeutics research programme is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Lab facilities Health, Medical and Neuropsychology
Psycho-physiological studies for health and disease.
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Why Leiden University?
We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.
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New techniques for tuberculosis treatment
About nine million people worldwide contract tuberculosis each year. Research into new treatment for this disease has received fresh stimulus with more efficient techniques and a new understanding of how the tuberculosis bacteria works.
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Leiden students develop high contagious card game
Infecting each other with viruses and bacteria while protecting yourself with medicines and vaccinations. Sounds like a fun evening, right? Master students Life Science & Technology Rafael Jezior and Dennis de Beeld certainly think so. Together, they developed ImmunoWars: an exciting card game based…
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LUMC involved in development of novel drugs to treat and prevent SARS-CoV-2 and other coronaviruses
The Department of Medical Microbiology at Leiden University Medical Center (LUMC) is researching antiviral drugs that could treat and prevent SARS-CoV-2 in various projects. One part of the PanCoroNed project is being led by Martijn van Hemert and involves lab tests into the antiviral effect of molecules…
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Abstract patterns and representations: the re-cognition of geometric ornament
On May 17th, Arthur Crucq succesfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Arthur on this great result.
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This Week’s Discoveries | 15 November 2016
Lecture
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Immune responses against conserved influenza epitopes: Lessons for peptide vaccination strategies
PhD Defence
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Testing of a malaria vaccine gets the green light
Researchers at Leiden University Medical Center (LUMC) and Radboud university medical center have been given the green light to deliberately infect volunteers with malaria in order to test a highly promising vaccine on them.
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Regulation of DNA damage and immune response pathways by post-translational protein modification
PhD Defence
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The immune compartment at the maternal-fetal interface throughout human pregnancy
PhD Defence
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Immune modulation by helminths and the impact on the development of type 2 diabetes
PhD Defence
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Immune modulation by schistosomes:mechanisms of regulatory B cell induction and inhibition of allergic asthma
PhD Defence
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Respiratory tract infection: prevention, early detection and attenuation of immune response
PhD Defence
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Genetic manipulation and genetic-based dissection of tumor-specific immunity
PhD Defence
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Exploring and Modulating the Tumor Immune Microenvironment Towards improving patient outcomes of immunotherapy in lung cancer
PhD Defence
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resistance of Human papillomavirus- infected or -transformed cells to Th1 immunity
PhD Defence
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High-dimensional profiling of immunotherapy responsive immune cells in cancer
PhD Defence
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Wiles and Wanderings: Immune-evasive maneuvers of skin-penetrating parasites
PhD Defence
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Music Cognition
Knowledge and culture subproject 1:
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Safety and efficacy after immunization with Plasmodium falciparum sporozoites in the controlled human malaria infection model
PhD Defence
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Outcome after Paediatric Stem Cell Transplantation for Inborn Errors of Immunity
PhD Defence
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T cell immunity against MHC-I low tumors in mouse models
PhD Defence
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Control of Western flower thrips through jasmonate-triggered plant immunity
PhD Defence
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Mast cell mediated immune modulation in experimental Rheumatoid Arthritis and atherosclerosis
PhD Defence
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metabolomics to probe oxidative stress, inflammation and systemic immunity
PhD Defence
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Immune regulation by CD4+CD49b+ T cells & B cell responses in arthritis
PhD Defence
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Immune parameters affecting maternal tolerance towards the fetus in normal and aberrant pregnancies
PhD Defence
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The Anti-Citrullinated Protein Antibody immune response and its effector functions in Rheumatoid Arthritis
PhD Defence
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Insights from modeling metabolism and amoeboid cell motility in the immune system
PhD Defence
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Chemical Synthesis of Fragments of Streptococcal Cell Wall Polysaccharides
This thesis describes the design and synthesis of fragments of various cell wall carbohydrates of the Streptococcus species, including the branched Group B-specific antigen (GBC) of Group B Streptococcus, glycerol phosphate (GroP) modified group A carbohydrate (GAC), and the O-acetylated type 1 capsular…
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Development of an effective, safe, and painless intradermal tuberculosis vaccine based on microneedles loaded with antigen-containing nanoparticles
Tuberculosis (TB) is a major global health problem caused by the bacterium Mycobacterium tuberculosis (Mtb). In 2015, there were estimated to be 10.4 million new cases and 1.8 million deaths ascribed to TB, making it one of the top 10 causes of death worldwide. Unfortunately, the only current registered…
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The road to insurmountability: Novel avenues to better target CC Chemokine receptors
This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.
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The serosa: an evolutionary novelty in insect eggs
What is the function of the insect serosa?
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Precision modeling of breast cancer in the CRISPR era
The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.
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Development & Disease in Animal Sciences
Animal Sciences’ contributions to the Development & Disease research theme include the mechanisms and evolution of embryonic development, the development of cognitive mechanisms, and animal models for understanding mechanisms of human disease.
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Chemical tools to study lipid signaling
Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.
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Chitin in the fungal cell wall: towards valorization of spent biomass of Aspergillus niger
Aspergillus niger is an important industrial producer of organic acids and enzymes producing large amounts of spent fungal biomass.