Patients with skin diseases such as eczema and psoriasis, sometimes spend a lifetime searching for the right medication. To help these patients faster and better, scientists across the country are joining forces. The Next Generation ImmunoDermatology (NGID) project, with LACDR professor Robert Rissmann…

Do large deletions represent a risk during CRISP/CAS9-mediated genome editing in plants?

The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…

Online teaching has made it much easier for international students to join in our courses. The Leiden minor in Global Health, for instance. Students from Tanzania, Rwanda, Uganda and Malawi logged on and made a valuable contribution with their knowledge, about tropical diseases, for instance.

In the Leiden University Medical Centre (LUMC) we strive to improve health care and the health of people.

What is the role of auxin in the initiation and process of somatic embryogenesis?

As part of the NEXUS1492 project, this project will use ancient DNA techniques to shed new light on the demographic and health history of the Caribbean and the impact of European colonization on indigenous communities in the region.

A cancer pill, preferably without severe side effects, is something we’d all welcome. Is it a matter of time before such a pill is a reality? We put this question to three Leiden researchers and asked how they themselves are contributing to new cancer treatments.

The structure of bacterial cells provides crucial clues about their interaction with their host. What are the key structural features of a bacterial cell that determine pathogenicity? What roles do these structures play in the life cycle, and how do they change during the infection process?

A vitamin D deficiency is often associated with smoggy English industrial cities during the Industrial Revolution, but research carried out on skeletons now suggests that the ‘English disease’ was also prevalent in rural areas of the Netherlands. Doctoral defence on 29 January.

Heart failure is a major health care problem with high mortality.

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

Good news for international collaboration: the EU’s International Credit Mobility programme has awarded 163 grants to students and researchers from Leiden University and partner universities in 19 countries outside the EU. The grants are for 19 projects that have arisen from existing partnerships.

Latin America matters! With its rich history, culture, its impressive resilience and creative innovation in the face of such a diverse array of challenges, Latin America can indeed show the way forward inspiring for positive change. Working together with Latin American institutions, our researchers…

Four Leiden researchers have each been awarded a consolidator grant of up to 2 million euros by the European Research Council (ERC). They carry out research on a diverse range of subjects, from gender stereotyping in the field of science to making sugar molecules.

Changes in our climate, the decline in biodiversity, the development of vaccines against new infectious diseases and whether we are the only inhabitants of the universe: these are just a few of the pressing challenges our society faces today. But which scientific choices must be made at the national…

A team of students from Leiden won the iGEM international biology contest in 2020 with their Rapidemic mobile testing kit. The kit makes it easy to detect viruses. The team has now been nominated for the Most Innovative Student in the Netherlands prize. Cast your vote and help them develop their inv…

From business administrator to engineer and from communication professional to agronomist. Whether you want to improve the world or your chances on the job market, you can continue to develop your skills at university throughout your life. Today, the universities of the Netherlands launched the new…

An international consortium of research groups is aiming to develop novel antibiotics against the tuberculosis bacteria and two other deadly bacteria. The European Union has awarded a total of 18 million euros to the RespiriTB and RespiriNTM projects. Researchers from the Leiden University Medical Centre…

Together with patient representatives, clinician-researchers from Radboucumc (Internal Medicine) Amsterdam UMC and researchers from Leiden University (Andrea Evers and Henriët van Middendorp) have received the Medical Inspirator Prize 2019 of The Netherlands Organisation for Health Research and Development…

Leiden professor of Cellular Immunology of Parasitic Infections Maria Yazdanbakhsh receives the prestigious NWO Spinoza Prize this year. This, in many ways, border-crossing scientist contributes with her research to more effective vaccines against parasitic infections and better medication for inflammatory…

Can we enhance the capacity of host immune cells to kill mycobacteria via production of reactive nitrogen species?

Promotores: Prof. Dr. Th.J.C. van Berkel, Prof. Dr. M. van Eck

Which plant leaf characteristics are involved in thrips resistance in tomato?

Biosynthetic gene clusters (BGCs) for natural products are widespread in microbial genomes, and they are rapidly exchanged. This research assesses the factors that control the spread of BGCs and resistance genes in nature. This includes risk assessment for the spread of engineered DNA in nature.

As a new vision on food production, the feasibility study on LED light to grow crops with the biological- and chemical evaluation of final products.

Researchers at Leiden University Medical Center (LUMC) and Radboud university medical center have been given the green light to deliberately infect volunteers with malaria in order to test a highly promising vaccine on them.

The pandemic has challenged us to revisit the way we structure education and how to reach out to students remotely. It almost seems fitting that a course devoted to a topic so closely related to the context of the corona crisis, that of global health, would explore the possibilities of making the course…

The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?

Promotor: S.M. Verduyn Lunel

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman

Our ability to learn and control movements is essential for engaging in goal-directed behaviour. From buttoning your shirt and driving a car, to cooking dinner and brushing your teeth -- our actions in daily life rely on this ability.

A multi-disciplinary approach to past lifestyles and cultural practices

Early treatment benefits patients who have not fully developed rheumatoid arthritis but are in the preliminary stages of the disease. This is what researchers from the Leiden University Medical Centre (LUMC) have reported in The Lancet. Patients in the pre-arthritis stage who were temporarily prescribed…

What is the function of the insect serosa?

Can birds - like people- ‘see’ voices and learn how to sing by listening and watching?

Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?

Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

Researchers in Bilthoven, The Netherlands, have recently unraveled the defense against whooping cough bacteria in unprecedented detail. The outcome of the project, conducted at Intravacc (Institute for Translational Vaccinology) in Bilthoven, provides opportunities for a new approach in the development…

A coronavirus booster shot provides a better immune response against COVID-19 than a single vaccine dose. mRNA boosters are the most effective upon receiving Janssen. These are the results of a collaborative study between several organisations, including the Leiden University Medical Center (LUMC).…

Can drug screening for tuberculosis treatment be made more efficient?

Imagine that you have a chronic skin condition, characterized by red patches of itchy, scaly skin. You regularly notice people staring at your skin and sense their reluctance to shake your hand. Or imagine that you have Parkinson's Disease, causing your hands to tremble and making it difficult for you…

1. What is the exact role of PIN proteins in PAT? 2. How is PIN polarity established, and how is it modulated by AGC kinase-mediated phosphorylation? 3. What is the role of the AGC kinase, as modulators of PAT, in translating environmental signals, such as gravity, light or mechanical stress, to plant…

Lecture, History Brown Bag Seminar