The rapid advances in imaging technology enable to see inside the body with ever increasing detail.

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This specialisation focuses on two important trends in health care: early diagnosis and developing the most targeted patient-specific treatment possible with the shortest possible recovery time and minimal side effects.

On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…

On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…

Promotores: S.J. Edixhoven, P.Parent

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PLATO is a centre for research and development in education and training. 4 areas of expertise and 4 methods.

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To study how planetary systems come into existence we study much younger systems still in formation.

In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…

Zebrafish is an excellent model organism for studying various human diseases. Due to opaqueness of the adult phase, in vivo studies are restricted to early embryonic stages. This raises the need for rapid sensitive and non-invasive in vivo imaging methods to follow developmental processes, not only…

From surface science towards industrial practice using high-pressure scanning tunneling microscopy.

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One of the ways of understanding another culture better is to examine what people experience when they read a text, or look at an image. Leiden experts have a lot of knowledge in this field, for example on culture in ancient Japan.

Promotor: M.A.G.J. Orrit

PhD Defence

Science

In this project we develop algorithms to automatically detect a particular type of archaeological sites in satellite images of the Alps.

Optical projection tomography (OPT) is a tomographic 3D imaging technique used for specimens in the millimetre scale.

This thesis focuses on the study of transient and variable radio sources in the universe.

The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

The aim of this project is to study what makes an act or form of violence a specifically political reality.

In Shimmering Images, Eliza Steinbock traces how cinema offers alternative ways to understand gender transitions through a specific aesthetics of change.

How do documentary moving images and fictional narratives involve and evolve each other?

This project aims to study the Aesopian fable from 1500 to the present day in its complex relationship between text, illustration and education, adopting a broad, transnational perspective.

Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

In 2018, the number of mobile phone users will reach about 4.9 billion. Assuming an average of 5 photos taken per day using the built-in cameras would result in about 9 trillion photos annually.

The most famous monument of the Dutch Golden Age is undoubtedly the Amsterdam Town Hall by architect Jacob van Campen inaugurated in 1655.

PhD Defence

In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.

Which immune mechanisms are involved in host defense against Staphylococcal infection?

This thesis describes the development and validation of new high-contrast imaging techniques, with the ultimate goal of enabling the next generation of instruments for ELT-class telescopes to directly image Earth-like extra-solar planets orbiting around nearby stars.

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).

Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek

Promotor: B. van de Water, Co-Promotores: J.H.N. Meerman, F.J. Verbeek

Promotor: C.U. Keller, Co-Promotor: F. Snik

Promotor: H.J.M. de Groot, Co-Promotor: A. Alia

A technique originally developed for satellite imaging can now be used to recover pictographic texts from underneath the surface of a five hundred year old Mexican manuscript.

The Animated Image addresses the entire range of contexts in which images were described by Roman authors as being animated, as well as the accounts that Roman writers produced to explain the animation of inanimate matter.

Imaging and Imagining Palestine is the first comprehensive study of photography during the British Mandate period (1918–1948).

Analysis of drug adversity

In Film and Video Intermediality, Janna Houwen innovatively rewrites the concept of medium specificity in order to answer the questions “what is meant by video?” and “what is meant by film?”

Lecture

Bispecific antibodies with one Fab arm binding to effector cells, such as T-cells and NK-cells, while the other Fab arm recognizing a tumor associated antigen (TAA) can be used to redirect these effector cells for tumor specific killing. Using bispecific antibodies to treat hematological cancers is…

In this thesis we investigated the ability of two-photon multifocal microscopy for single-molecule microscopy in live cells and organisms.

Compact Cinematics challenges the dominant understanding of cinema to focus on the various compact, short, miniature, pocket-sized forms of cinematics that have existed from even before its standardization in theatrical form, and in recent years have multiplied and proliferated, taking up an increasingly…