24 search results for “hydrogels” in the Public website
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Dynamic hydrogels as synthetic extracellular matrices for three- dimensional cell culture
Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.
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Supramolecular polymer materials for biomedical applications and diagnostics
Self-assembly is an abundant process in nature and is vital to many processes in living organisms.
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Squaramide-based supramolecular materials for 3D cell culture applications
A new type of tripodal squaramide-based supramolecular hydrogels is developed and studied.
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Design and application of dextran based cross-linked networks
This thesis describes the design, characterization and application of dextran based crosslinked network.
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Roxanne Kieltyka
Science
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Giant unilamellar vesicles: An efficient membrane biophysical tool and its application in drug delivery studies
Promotor: A. Kros
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Self-assembly properties and applications of metal-binding peptides and proteins
It is estimated that approximately 30% of all proteins require a metal to function. Investigating the relationship between metal-binding and peptide/protein folding allows us to uncover fundamental rules for creating metallo-peptides and proteins, which in turn leads to the creation of new structures,…
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Supramolecular materials: from biosensors to cell delivery devices
The group of Dr. Roxanne Kieltyka designs and synthesizes molecules that self-assemble into polymeric materials using specific non-covalent interactions. These substrates can be used for numerous applications in medicine ranging from disease detection to cell delivery depending on the (bio)molecular…
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Elastic Leidenfrost Effect enables soft engines
Water droplets float in a hot pan because of the so-called Leidenfrost effect. Now physicists have discovered a variation: the Elastic Leidenfrost effect. It explains why hydrogel balls jump around on a hot plate making high pitched sounds. Publication in Nature Physics on July 24.
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Bouncing gel balls popular in the media
The explanation from physicist Scott Waitukaitis for the screaming and bouncing gel balls in a hot pan has been covered in several media, including the Washington Post.
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Dynamic hydrogels as synthetic extracellular matrices for three- dimensional cell culture
PhD defence
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Teaching
Research projects for students of the University of Leiden and other Dutch Universities are often available at the MacBio group. The research lines are also described in the Research section. For details of specific projects contact the supervisor (Ubbink, Dame, Boyle, Jeuken or Wentink).
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Delivery of Biotherapeutics
The Delivery of Biotherapeutics research group is led by Prof. Matthias Barz and focusses on the synthesis and characterization of polypept(o)ids and their application in nanomedicine to improve existing therapies or enable novel diagnostic or therapeutic approaches.
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Cuba
This is an Erasmus+ International Credit Mobility project of Leiden University Medical Centre with University of Havana.
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Elastic Leidenfrost Effect on cover of Nature Physics
First author Scott Waitukaitis and principal investigator Martin van Hecke have made the cover of Nature Physics with their publication on a newly discovered effect. The Elastic Leidenfrost effect explains why hydrogel balls jump around on a hot plate making high pitched sounds.
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‘I am curious and full of passion for understanding molecular chemistry’
Since May, Assistant professor BioTherapeutics Lu Su works in our faculty. Although she is still young, she already worked in many different fields and co-operated on two publications in big scientific journals. How did she become so successful and what motivates her to keep researching the possibilities…
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New insights on graphene
Graphene floating on water does not repel water, as many researchers believe, but rather attracts it. This has been demonstrated by chemists Liubov Belyaeva and Pauline van Deursen and their supervisor Grégory F. Schneider. Publication in Advanced Materials.
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NWO Veni Grant for Bouncing Balls on Hot Plate
Physicist Scott Waitukaitis receives an NWO Veni grant to research the Leidenfrost effect for squishy materials. This effect is well-known for dancing water droplets in a frying pan.
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Supramolecular and Biomaterials Chemistry
Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…
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DNA as a supramolecular building block
PhD student Willem Noteborn has investigated supramolecular structures. These can be useful for the loading of medicines and signalling molecules regarding, for example, cellular differentiation. In his thesis, he describes the functioning of these structures.
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Leiden iGEM students win prize with squid protein
The Leiden students who participated in the iGEM synthetic biology competition have won the prize for best production. They developed a way to have bacteria produce the substance suckerine, a protein derived from the Humboldt squid. By doing so, they want to help heal burn wounds. ‘The announcement…
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Reedijk Symposium 2014 - Guest Lecturers: Prof. Alan Rowan & Prof. Matthew Neurock
On Friday October 31st 2014 the fourth annual Jan Reedijk LIC Symposium will be held. The main lectures of the day will be
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ICM 2018 project results
Within the ICM 2018 project, Leiden University cooperated with 25 partner universities from 14 countries. In total, 97 mobilities were granted to this project - 65 mobilities were realised (some mobilities had to be ended prematurely due to covid-19, others were finished online).
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Veni grants for 19 young Leiden researchers
Nineteen researchers who have recently been awarded their PhD are to receive a Veni grant of up to 250,000 euros. Science funding agency NWO has awarded a total of 158 Venis in this round; Leiden University's share of the awards is 12 percent.