Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

This thesis describes the design, characterization and application of dextran based crosslinked network.

Promotor: A. Kros

It is estimated that approximately 30% of all proteins require a metal to function. Investigating the relationship between metal-binding and peptide/protein folding allows us to uncover fundamental rules for creating metallo-peptides and proteins, which in turn leads to the creation of new structures,…

Water droplets float in a hot pan because of the so-called Leidenfrost effect. Now physicists have discovered a variation: the Elastic Leidenfrost effect. It explains why hydrogel balls jump around on a hot plate making high pitched sounds. Publication in Nature Physics on July 24.

The group of Dr. Roxanne Kieltyka designs and synthesizes molecules that self-assemble into polymeric materials using specific non-covalent interactions. These substrates can be used for numerous applications in medicine ranging from disease detection to cell delivery depending on the (bio)molecular…

The explanation from physicist Scott Waitukaitis for the screaming and bouncing gel balls in a hot pan has been covered in several media, including the Washington Post.

Research projects for students of the University of Leiden and other Dutch Universities are often available at the MacBio group. The research lines are also described in the Research section. For details of specific projects contact the supervisor (Ubbink, Dame, Boyle).

The Delivery of Biotherapeutics research group is led by Prof. Matthias Barz and focusses on the synthesis and characterization of polypept(o)ids and their application in nanomedicine to improve existing therapies or enable novel diagnostic or therapeutic approaches.

First author Scott Waitukaitis and principal investigator Martin van Hecke have made the cover of Nature Physics with their publication on a newly discovered effect. The Elastic Leidenfrost effect explains why hydrogel balls jump around on a hot plate making high pitched sounds.

Graphene floating on water does not repel water, as many researchers believe, but rather attracts it. This has been demonstrated by chemists Liubov Belyaeva and Pauline van Deursen and their supervisor Grégory F. Schneider. Publication in Advanced Materials.

This is an Erasmus+ International Credit Mobility project of Leiden University Medical Centre with University of Havana.

Physicist Scott Waitukaitis receives an NWO Veni grant to research the Leidenfrost effect for squishy materials. This effect is well-known for dancing water droplets in a frying pan.

Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…

PhD student Willem Noteborn has investigated supramolecular structures. These can be useful for the loading of medicines and signalling molecules regarding, for example, cellular differentiation. In his thesis, he describes the functioning of these structures.

On Friday October 31st 2014 the fourth annual Jan Reedijk LIC Symposium will be held. The main lectures of the day will be "Strain Stiffening - The key to Biomimetic Cytoskeletal Materials" by invited speaker Prof. Alan Rowan (Radboud University), and "Engineering Molecular Transformations over Supported…

The Leiden students who participated in the iGEM synthetic biology competition have won the prize for best production. They developed a way to have bacteria produce the substance suckerine, a protein derived from the Humboldt squid. By doing so, they want to help heal burn wounds. ‘The announcement…

Lecture

Nineteen researchers who have recently been awarded their PhD are to receive a Veni grant of up to 250,000 euros. Science funding agency NWO has awarded a total of 158 Venis in this round; Leiden University's share of the awards is 12 percent.