uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.

One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.

Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria.

How have human-environmental entanglements changed in the Gulf of San Miguel, Darien, Panama, from the first traces human practices through to the present?

Lecture

In Humanity’s End As A New Beginning, Emeritus Professor Mineke Schipper reflects on myths about ‘the end’.

This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.

Does foreign aid promote human rights?

Prediction of human (CNS) target site concentrations in health and disease In the vision of Prof. de Lange we will only be able to predict human (central nervous system, CNS) target site concentrations and effects if we perform systematic, condition-dependent, integrative, and strictly quantitative…

How can zebrafish research help to understand and fight human cancer?

When do fire making tools appear in prehistory, and how might the use of these tools manifest in the archaeological record?

The studies described in this thesis deal with glycosidases, in particular alpha-galactosidases.

The factors that dynamically sculpt the inter-regional correlation of brain patterns are poorly understood. Here, we test the hypothesis that they are shaped by the catecholaminergic neuromodulators norepinephrine and dopamine.

We investigate bacteria and fungi to understand their malicious or beneficial impact on food crops and their pathogenic or antibiotic role in human health.

Our in-house human skin equivalents contain all stratum corneum (SC) barrier lipid classes, but have a reduced level of free fatty acids (FAs), of which a part is mono-unsaturated. These differences lead to an altered SC lipid organization and thereby a reduced barrier function compared to human skin.…

New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.

Promotor: G.R. de Snoo, W. Kustiawan, Co-promotor: H.H. de Iongh

Workshop

This summer school focuses on the emergence of sexual orientation, gender identity (SOGI) and intersex issues in different areas of international law, such as human rights law, refugee law and international criminal law. Information about the next edition will be published soon!

In the last weeks, ASEAN published different Statements about the human rights situation in Myanmar and the Democratic People´s Republic of Korea (DPRK).

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

Seasonal influenza vaccines provide protection against matching influenza A virus (IAV) strains mainly through the induction of neutralizing serum IgG antibodies. However, these antibodies fail to confer a protective effect against mismatched IAV. This lack of efficacy against heterologous influenza…

Poly(lactic-co-glycolic acid) (PLGA) particles have been extensively studied as biodegradable delivery system to improve the potency and safety of protein-based vaccines. In this study we analyzed how the size of PLGA particles, and hence their ability to be engulfed by dendritic cells (DC), affects…

On Thursday 20 May 2021, Tania Li delivered the annual Van Vollenhoven Lecture.

Vocal learning is a trait shared by songbirds and humans. It is also a trait that is restricted by the brain rather than by a species' vocal apparatus. In this dissertation, functional MRI is employed in both species in order to explore potential common neural mechanisms underlying the ability to develop…

The advanced insights obtained for the CNS PBPK model development are currently used to develop advanced mathematical models for drug distribution prediction in other body tissues protected by barriers, such as the gut. The gut PBPK model will be linked to drug effects for treatment of colon cancer.

On Wednesday 13 December, Melanie Fink will defend her doctoral thesis ‘Frontex and Human Rights: Responsibility in “Multi-Actor Situations” under the ECHR and EU Public Liability Law’. The defence will take place at 10.00 hrs at the Academy Building of Leiden University, Rapenburg 73. The supervisors…

For more information regarding ongoing research projects, please contact Prof. Johan Kuiper.

Collecting as much information as possible about administering a new medicine to people can save a lot of money.

The Sackler Distinguished Lecture Series on Human Rights was established at Leiden University through an endowment given by Dr. Raymond R. Sackler and his wife, Beverly, international philanthropists with a commitment to supporting scientific research. The lectures mark the annual celebration of International…

The third and final participation session was held on 20 September; the evening was attended by local residents, business owners, students and other stakeholders.

To celebrate the end of the semester the Science and Humanities Buddy Programme organised a barbecue together, which has become a small tradition. The barbecue marks the third co-organised activity between the two Programmes and helps to bring international and Dutch students together. The Buddy Programme…

You can ask virtual assistant Siri about the weather, but you can’t have a real conversation with it yet. You can’t refer to anything that’s been said before, or ask the system why it says what it says. Stephan Raaijmakers, Professor by Special Appointment from TNO, hopes to change this.

On 1 October 2019 the Hazelhoff Centre for Financial law hosted its 19th guest lecture starring Paul Sharma, managing director at Alvarez & Marsal and co-head of the European Financial Industry Regulatory Advisory Services practices.

On 7 May 2020, Jolanda van der Vliet defended her thesis 'The International Legal Protection of Environmental Refugees. A human rights-based, security and State responsibility approach'. The doctoral research was supervised by Prof. N.J. Schrijver and Prof. J.J.C. Voorhoeve.

Promotores: G.R. de Snoo, B. Sinsin, Co-Promotor: H.H. de Iongh

If an algorithm has to learn to understand language, simply having a lot of data doesn’t help much. Like us, a computer has to learn the language in interaction with others. Tessa Verhoef is fascinated by how this interaction works.

What do a linguist, an artist, a Professor of Conservation and Restoration, and a lecturer at the Leiden Institute of Advanced Computer Science have in common? They all use Artificial Intelligence. On 7 April they discussed the use of AI at Leiden’s Kijkhuis cinema.

Leiden University and the Municipality of Leiden will develop new plans for an alternative Humanities Campus in the city centre. This means they will not proceed with the compulsory purchase of the De Doelen housing complex to facilitate the construction of the new Humanities Campus. The plans to demolish…

On 22 March 2016, Prof. Carsten Stahn spoke on prosecuting Human Trafficking as a Crime Against Humanity at a Conference on International Criminal Justice, hosted by the Collaborative Innovation Center of Judicial Civilization of Zhejing University in Hangzhou, China.

Leiden University can build an alternative Humanities Campus on its own available land at the current location in the city. This is the conclusion of a feasibility study and is what the mayor and aldermen of Leiden write in a letter to the city council.

The renovation of Cluster Zuid (Van Eyckhof-Van Wijkplaats) is the third project in the development of the Humanities Campus. The circular dismantling of Cluster Zuid has started.

Two Vidi subsidies for Faculty of Archaeology.

The Faculty of Humanities is ranked 25th within the subject area 'Arts and Humanities' in the Times Higher Education Ranking (THE) of 2014-2015. The faculty scores particularly high in teaching, research and international outlook.

Friday October 24th Honours students had to present their case studies on a topical issue related to Humanities. All Honours students made posters in pairs of two and had to defend their case in front of an audience at the Old Observatory. It was a tense experience, since they were being graded by…

Humanities Faculty Leiden occupies a 49th place in the field of Arts & Humanities in the QS World University Ranking. Especially the subject areas Linguistics and History & Archeology rank high, with respectively a 26th and 28th place. Leiden University has fallen by one place in the annual QS World…