The Leiden Institute of Chemistry (LIC) is the basis for research and collaborations of the Leiden chemistry groups. Chemistry is the central science enabling a healthy future in a sustainable society. Chemistry researchers at Leiden University take a fundamental approach in finding tailored solutions…

To achieve a more sustainable society, it is important to move away from cradle-to-grave applications, and to develop a more circular economy, wherein reusability and recycling are part of the development of any new product. In that context, the currently undergoing change of chemical feedstocks from…

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The term “Lone Actor” has been applied to a variety of violent individuals who are thought to act out of ideological motivations using terrorist tactics.

Curved single crystals provide variable, but well-defined surface structures.

In the research programme Microbial Sciences we perform state-of-the-art research in the field of biotechnology and microbial sciences.

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PhD defence

The electrochemical reduction of a group of organic compounds on platinum is strongly dependent on the arrangement of the atoms in the platinum surface. Christoph Bondue, postdoc in Marc Koper's group, published this in Nature Catalysis on 4 March. The reduction of such compounds is an important process…

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Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

Macromolecular Biochemistry is a section of the Leiden Institute of Chemistry at Leiden University, comprising the PIs Marcellus Ubbink, Remus Dame, Aimee Boyle, Lars Jeuken and Anne Wentink.

Leiden University has developed a radically different method for large scale production of diverse nanoparticles and their alloys.

PhD defence

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PhD defence

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

The Assyrian Empire was the first state to achieve durable domination of the Ancient Near East, enduring some seven centuries and, eventually, controlling most of the region. Yet, we know little about how this empire emerged from a relatively minor polity in the Tigris region and how it managed to consolidate…

Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.

Employer organizations have been presented as strong promoters of the liberalization of industrial relations in Europe. This article, in contrast, argues that the preferences of employers vis-à-vis liberalization are heterogeneous and documents how employer organizations in Spain, Italy, and Portugal…

Developing robust and comprehensive analytical methods to size and quantify subvisible particles in biopharmaceutical products.

Homicide followed by the suicide of the perpetrator often leads to shock and incomprehension. It has been suggested that media reporting on such cases could lead to an imitation effect.

Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.

Eine Analyse materieller Kultur römischer Kolonien in der Mikroregion von Suessa Aurunca, Minturnae und Sinuessa

Promotor: B. van de Water, Co-Promotores: J.H.N. Meerman, F.J. Verbeek

Bruno Munari (1907–1998) was a prolific and influential artist, designer, and writer. Alessandro Colizzi’s study is the first extensive, detailed record of Munari’s graphic design production, and as such provides a substantial base for a full understanding of his oeuvre.

Wim Klooster and Gert Oostindie present a fresh look at the Dutch Atlantic in the period following the imperial moment of the seventeenth century. This epoch (1680–1815), the authors argue, marked a distinct and significant era in which Dutch military power declined and Dutch colonies began to chart…

Promotor: H.J.M. de Groot, Co-Promotor: A. Alia

Promotor: W. Jiskoot, Co-promotor: A. Hawe

Throughout history, a large portion of the world's population has lived under imperial rule. Although scholars do not always agree on when and where the roots of imperialism lie, most would agree that imperial configurations have affected human history so profoundly that the legacy of ancient empires…

Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh

Antibiotic resistance, caused by widespread use of antibiotics, leads to bacterial infections that are difficult, if not impossible, to treat and is a major worldwide health concern.

Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

What are the circadian disturbances underlying depression vulnerability? How are they related to mood, cognition and sleep ?

This dissertation develops an innovative approach to cultural transformation in the kingdom of Commagene (modern south-east Turkey) during the 1st c. BCE, focusing on a palatial context in the capital Samosata.

When to launch a next-generation product in a competitive market and how much capacity should be allocated to it

Both Leon Jacobse and Thom Hersbach from Marc Koper's research group obtained their PhDs cum laude. They both investigated changes on the surface of a platinum electrode. Jacobse studied this at a positive voltage, Hersbach at a negative voltage. Platinum has the potential to convert renewable energy…

How can we make the information in handwritten historical research reports accessible and searchable? Data scientists at Leiden University are working with other universities on a method that will improve access to cultural heritage.

Promotor: H.J.M. de Groot

In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.

Some children and adolescents find it hard to attend school because of anxiety and/or depression, a problem which is often referred to as school refusal. The main research question is how we can best help these young people reduce their emotional distress and increase their school attendance in order…

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PhD defence

Research training projects in the MCBIM group - Bachelor and master students of all chemistry related studies are more than welcome to take part in our research activities. We have various research projects, all in one way or another involving transition metal ions. Daily supervision in the laboratory…

Research at the BPOC/SSNMR group is comprised of the following research themes:

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Commentators and scholars view both social media and cities as sites of fragmentation. Since both urban dwellers and social media users tend to form assortative social ties, so the reasoning goes, identity-based divisions are fortified and polarization is exacerbated in digital and urban spaces.

Valérie Pattyn, Assistant Professor at Leiden University, researched