2,533 search results for “heart and vascular disease” in the Public website
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Annemarie Meijer
Science
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Behind the scenes of the Dutch Central Bank
A lecture about the drive, dynamics and dilemmas of our central bank and supervisor. Joanne Kellerman discussed the role of DNB, the central bank in our country for already 200 years, and the dilemmas that a supervisor faces. How can be ensured that a supervisory intervention is rightly timed and that…
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20th century changes in the Dutch flora
Description of 20th century changes in the Dutch flora: Description and interpretation (1999 - 2005)
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Mycobacterial cell wall-deficiency and its role in the persistence of tuberculosis
What is the role of cell wall-deficiency in the persistence of tuberculosis?
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SKY HIGH: Vertical farming a revolution in plant production
As a new vision on food production, the feasibility study on LED light to grow crops with the biological- and chemical evaluation of final products.
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Marker assisted breeding for thrips resistance in tomato
Which plant leaf characteristics are involved in thrips resistance in tomato?
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Horizontal gene transfer and spreading of biosynthetic gene clusters and antimicrobial resistance
Biosynthetic gene clusters (BGCs) for natural products are widespread in microbial genomes, and they are rapidly exchanged. This research assesses the factors that control the spread of BGCs and resistance genes in nature. This includes risk assessment for the spread of engineered DNA in nature.
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Determining the kinetic profile of ENT1 inhibitors
Supervisor: Anna Vlachodimou
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Programme structure
The master's specialisation Health and Medical Psychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.
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Distance-based analysis of dynamical systems and time series by optimal transport
Promotor: S.M. Verduyn Lunel
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ImageInLife: Training European experts in multilevel bioimaging, analysis and modelling of vertebrate development
How can novel bioimaging technologies and vertebrate model species be used to gain a better understanding of early cellular behaviours with the ultimate goal to increase our understanding of human development and disease processes?
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Small changes for long term impact: optimization of structure kinetic properties: a case of CCR2 antagonists
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman
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Chemokine signaling in Tuberculosis and Salmonella infection
Who benefits from CXCR/CXCL chemokine signaling during infection: host or pathogen?
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Topic: Movement and mental functions
Our ability to learn and control movements is essential for engaging in goal-directed behaviour. From buttoning your shirt and driving a car, to cooking dinner and brushing your teeth -- our actions in daily life rely on this ability.
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Teeth Tell Tales
A multi-disciplinary approach to past lifestyles and cultural practices
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The serosa: an evolutionary novelty in insect eggs
What is the function of the insect serosa?
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Targeted biomolecule production for therapeutic use
We aim to develop a drug-delivery method based on the production of biomolecules directly at the target site.
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‘Seeing voices’: the role of multimodal cues in vocal learning
Can birds - like people- ‘see’ voices and learn how to sing by listening and watching?
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MeRGeR: Physiological significance of the glucocorticoid and mineralocorticoid receptor signaling in the innate immune system
Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?
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Zebrafish: a new engraft model to study Ewing sarcoma progression
Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?
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LUMC to build largest stem cell facility in the Netherlands
The Leiden University Medical Center (LUMC) will start construction this year of the largest non-profit stem cell and gene therapy facility in the Netherlands, and one of the largest facilities in Europe. NECSTGEN – the Netherlands Center for the Clinical Advancement of Stem Cell and Gene Therapies…
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Veronique de Gucht
Faculteit der Sociale Wetenschappen
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Paul Hooykaas
Science
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Herman Spaink
Science
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Saving for discounts by living healthily
A new health programme will reward patients with - or at risk of developing - cardio-vascular diseases for keeping to a healthy lifestyle. A research group including psychologist Andrea Evers has been awarded 2.5 million euros by the Dutch Heart Foundation and the Ministry of Public Health, Welfare…
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Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
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Frank Schaftenaar
Science
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The quest for new medicines against tuberculosis
Can drug screening for tuberculosis treatment be made more efficient?
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Intramyocardial bone marrow cell injection for ischemic heart disease: efficacy analysis and long term follow-up
PhD Defence
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Polar auxin transport: translating environmental signals into plant developmental responses
1. What is the exact role of PIN proteins in PAT? 2. How is PIN polarity established, and how is it modulated by AGC kinase-mediated phosphorylation? 3. What is the role of the AGC kinase, as modulators of PAT, in translating environmental signals, such as gravity, light or mechanical stress, to plant…
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The Role of the innate and adaptive immune system in Vascular remodelling
PhD Defence
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Topic: Stigmatization in patients with chronic health conditions
Imagine that you have a chronic skin condition, characterized by red patches of itchy, scaly skin. You regularly notice people staring at your skin and sense their reluctance to shake your hand. Or imagine that you have Parkinson's Disease, causing your hands to tremble and making it difficult for you…
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Tenure Track position in development of biologics
Science, Leiden Academic Centre for Drug Research (LACDR)
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Leiden Professor convenes precision medicine workshop at Harvard's Radcliffe Institute
Professors Simcha Jong (Leiden University) and Rifat Atun (Harvard University) convened an exploratory seminar to discuss challenges for health systems in realising the potential of precision medicine at Harvard University’s Radcliffe Institute for Advanced Studies in Cambridge, MA on 17 April 2017.
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Development of an in vitro vascular network using zebrafish embryonic cells
PhD Defence
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Short-term Pre-operative Dietary Restriction in Vascular Surgery
PhD Defence
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Lung diseases
Inaugural Lecture
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Mathematical model helps to explain the formation of spine and ribs
Mathematical biologists from Leiden have developed a model that helps to explain how the spine and vertebrae, among other things, form during embryonic development. The same process, the other way around, plays a key role in cancer metastasis. Publication in iScience.
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Conquering the fortress: New strategies for the treatment of tuberculosis
Can we exploit the cell death machinery of the host to develop new host-directed anti-TB treatments?
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Imaging of biomaterial-associated inflammation and infection using zebrafish
Which immune mechanisms are involved in host defense against Staphylococcal infection?
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Novel immunomodulatory drugs for tuberculosis treatment
Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?
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Linking aboveground-belowground interactions and plant-soil feedback to improve pest control and sustainability in greenhouse cut-flowers
We examine how soil inoculation influences aboveground organisms (i) directly, and indirectly via (ii) its effects on plant chemistry or volatile emission, or via (iii) mediating the effects of belowground pathogens on aboveground organisms via the shared plant.
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Do fungi differ? Understanding the mechanisms of mycorrhizal fungal impacts on soil C sequestration
How presence, abundance and enzymatic activities of AM and EM fungi differently affect soil carbon sequestration processes?
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Understanding the role of mycorrhizas in global carbon cycle processes
How the global distribution of vegetation stands dominated by arbuscular and ectomycorrhizal plants relate to principle aspects of belowground carbon accumulation processes?
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Terrestrial field trials for side-effects of pesticides
The thesis describes terrestrial field trials aimed to detect side-effects of pesticides within the framework of pesticide registration procedures. Field trials were developed using vascular plants Brassica napus and Poa annua, caterpillars Pieris brassicae and effects on decomposition were studied…
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Vivian Kraaij
Faculteit der Sociale Wetenschappen
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Martijn van der Lienden
Science
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Micha Drukker
Science
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Humanities as the heart of Leiden in 2022: get to know the team
In 2022, Leiden will be the European City of Science. During this year, Leiden will be the European stage for knowledge, with a programme filled with science, art and culture. Of course, the humanities also take part. Get to know the core team of our faculty.
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Development of new antibiotics from plant-originated products
Utilization of plant-originated products as new antibiotics