486 search results for “gpcr stabilization” in the Public website
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PhD Theses
A full overview of MacBio PhD Theses.
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Anthropogenic effects on links between macro-invertebrate diversity and ecosystem functioning
How are links between macro-invertebrate diversity and ecosystem functioning influenced by anthropogenic pressures?
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Pleading for Diversity: The Church Caspar Coolhaes Wanted
Linda Stuckrath Gottschalk defended her thesis on 6 April 2016.
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Why Leiden University?
We are committed to provide you a meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.
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Chara
The Green algae Chara as model system for intra and inter cellular transport processes.
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Behind the scenes of the Dutch Central Bank
A lecture about the drive, dynamics and dilemmas of our central bank and supervisor. Joanne Kellerman discussed the role of DNB, the central bank in our country for already 200 years, and the dilemmas that a supervisor faces. How can be ensured that a supervisory intervention is rightly timed and that…
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Europe as A Global Actor? – The Common Security and Defence Policy in Question
My research project aims to analyze reasons of the European Union’s (EU) inadequacy to develop a strong Common Security and Defense Policy (CSDP) with regard to the role of main EU member states, namely Germany and the United Kingdom (UK) and find the answer of how the EU overcome the CSDP question…
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Delivery of Biotherapeutics
The Delivery of Biotherapeutics research group is led by Prof. Matthias Barz and focusses on the synthesis and characterization of polypept(o)ids and their application in nanomedicine to improve existing therapies or enable novel diagnostic or therapeutic approaches.
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Balance between an Emerging Regional Legal Order and Inter-regional Cross-border Insolvency – Challenges Faced by CICIA
In pursuit of solutions to China’s inter-regional cross-border insolvency cooperation, my doctoral dissertation provides 10 original recommendations accompanied with comments, which are entitled “China’s Inter-regional Cross-border Insolvency Arrangement” (CICIA).
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Intracellular Transport
Bead microrheology: Analysis of active and passive transport in living cells
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European Union Studies (MA)
The master’s in European Union Studies at Leiden University covers the EU's broad geographical sweep from an interdisciplinary perspective.
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Cancer and heredity
Some people are predisposed to develop cancer. Mutations in genetic material that increase a person’s chances of developing cancer can already be present at birth. Researchers are closely examining these mutations to learn more about how cancer begins to develop.
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Book project
Book project
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Law & Finance (Advanced LL.M.)
Leiden University’s Master of Laws in Advanced Studies in Law and Finance (L.L.M.) examines the complex, international and multidisciplinary area of law and finance.
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GTGC Technology research seminar
On Wednesday the 1st of December, the thematic area on technology of GTGC organized its first research seminar, by Anna-Lena Rüland and Babak Rezaeedaryakenari. James Shires, together with his colleague Max Smeets at ETH Zurich, presented on their project "Cyberspace and (In)stability: The Structural…
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Matthias Haentjens and the second conference on bank resolution
On 3 February 2021, Prof. Matthias Haentjens spoke at the second conference on bank resolution, jointly organised by the European Banking Institute (EBI) and the Single Resolution Board (SRB).
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Monitoring Cytoskeletal Conductance Variation for Sensing Cancer Drug Resistance
Actin and microtubules form cellular cytoskeletal network, which mediates cell shape, motility and proliferation and are key targets for cancer therapy. Changes in cytoskeletal organization correlate with proliferative capacity and invasiveness of cancer cells. These changes expectedly lead to altered…
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Els de Busser on Panel during EuroDIG 2019
On 20 June 2019, dr. Els De Busser was a panelist during the EuroDIG 2019 Conference in The Hague at the World Forum.
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KNAW Early Career Award for ecologist Michiel Veldhuis
Curiosity is the driving force behind the research of ecologist Michiel Veldhuis. The associate professor investigates ecosystems in relation to climate change in the savannahs of Africa. More and more, he is also looking at social factors such as the influence of population growth. The KNAW rewards…
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New insights into chemical sensing of the human pathogen for cholera
The bacterium Vibrio cholerae is a serious threat to our health because it is the causative agent of cholera. Worldwide, over a billion people per year are at risk of cholera infection. New strains of V. cholerae are resistant to the multiple drugs used to treat cholera, meaning that new types of drugs…
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Publications
Here you can find our most recent research publications
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Complexity Models to Prevent Financial Crashes
The financial system needs complexity theory to predict economic crises like the 2008 meltdown. An international team of scientists, including Leiden physicist Diego Garlaschelli, state this in a paper published in Science on February 19th.
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The transformation of the euro
On Wednesday 31 January, at 15.00 hrs, Vestert Borger will defend his dissertation entitled ‘The Transformation of the Euro: Law, Contract, Solidarity’ in the Great Auditorium of Leiden University. The dissertation has been written under the supervision of Professor Stefaan Van den Bogaert (supervisor)…
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Impurities in sugar excipients could cause drugs to fail
Sugar excipients, needed to stabilize medicines, can be unsafe for patients due to an impurity discovered recently by Daniel Weinbuch. ‘The biopharmaceutical industry should now consider new excipient quality criteria for safer drug development,’ he says. PhD defence on 13 December.
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Leiden University strengthens its focus on Chemical Biology and Medicinal Chemistry with seven new group leaders
Tackling key challenges of Chemical Biology and Medicinal Chemistry to aid drug discovery is one of the focus areas of Leiden University. To this end, the Leiden Early Drug Discovery & Development network (LED3) was established by the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden…
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Collaborative and effective drug development
There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…
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Luke Dimitrios Spieker is awarded the Common Market Law Review Prize for young academics 2019
The Editorial Board is pleased to announce the result of the 2019 Common Market Law Review Prize for an article submitted by a young academic.
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MOOC The Changing Global Order
mooc Global Order Machtsverhoudingen International
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ASEAN and Human rights
In the last weeks, ASEAN published different Statements about the human rights situation in Myanmar and the Democratic People´s Republic of Korea (DPRK).
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Shuai Guo speaks at Global Bankruptcy Scholars’ Work-in-Progress Workshop in Brooklyn Law School, New York
Shuai Guo, PhD candidate at Company Law and the Hazelhoff Centre for Financial Law, was invited to speak about his research on cross-border bank resolution, with a comparative analysis of the EU, the US and China, at the Global Bankruptcy Scholars’ Work-in-progress Workshop held on 20-21 September at…
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European collaboration shines a light on enzyme discovery for industry
A European consortium has provided a disruptive technological breakthrough to allow the discovery and characterization of novel enzymes for industrial biotechnology. The technology will open the way to more efficient industrial processes such as in the biofuel, animal feed and paper and pulp industr…
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Asynchrony among plant communities stabilises ecosystem
Fluctuations in individual plant communities contribute to the stability of an ecosystem as a whole, a study published in Ecology Letters shows. Nadia Soudzilovskaia and colleagues for the first time used data from plant communities across five continents to prove this hypothesis.
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The Hague Program for Cyber Norms welcomes visiting fellow Caitríona Heinl
We are delighted to welcome Caitriona Heinl as Visiting Fellow of The Hague Program for Cyber Norms at Leiden University’s Institute of Security and Global Affairs from 22 January till 16 February 2018.
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This Week’s Discoveries | 22 March 2016
Lecture
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Chemical Probe Facility
The Chemical Probe Facility is part of the Leiden Early Drug Discovery & Development (LED3) center. Activity-based protein profiling (ABPP) is one of the pillars of chemical biology. ABPP determines the activity of entire protein families in living cells and tissues under physiological conditions, such…
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Elliot Mock
Our response to stress is regulated by the ‘bliss molecule’ anandamide but how exactly remained unknown. Until recently, that is. Elliot Mock has now succeeded in developing a new substance that reduces anandamide, called LEI-401. This has made it easier to conduct research into the role of anandamide…
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Too big to fool: moral hazard, bailouts, and corporate responsibility
On the 14th December 2016, Steven L. Schwarcz, Stanley A. Star Professor of Law and Business at Duke University School of Law gave the thirteenth Hazelhoff Guest Lecture. Professor Schwarcz questioned the often-heard assumption that systemically important financial institutions engage in excessive…
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Postdoctoral researcher in computational drug discovery
Science, Leiden Academic Centre for Drug Research (LACDR)
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Plenary speakers
The following speakers have agreed to give plenary talks.
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Structure and regulation in photosynthesis
Plants, algae and cyanobacteria have the amazing capacity to perform delicate photophysical and photochemical processes of light capture, excitation transfer, charge separation and catalysis in fluctuating living environments. As a consequence, photosynthetic proteins and membranes form dynamic architectures.…
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PhD in physical chemistry: operando spectroscopy on IrOx and RuOx electrocatalysts
Science, Leiden Institute of Chemistry (LIC)
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Prior Research
The van Exter group has an extensive history of prior research in classical and quantum optics. As former part of the group of Han Woerdman, we have studied topics as diverse as:
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Publications
Relevant publications of the CIGR participants.
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Full Professor in Artificial Intelligence and Data Theory
Medicine/LUMC, Science
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Bosnia
This is an Erasmus+ International Credit Mobility project of Leiden Law School with University of Sarajevo in Bosnia Herzegovina.
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Mapping Identity in Dutch Colonial Sri Lanka (1658-1796)
At the heart of this study is a thorough inquiry of categorisations of social identity used in the VOC’s record-keeping bureaucracy. How were service, occupational and caste groups classified and shaped by the VOC?
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The Hague Program for Cyber Norms
A research program that focuses on the development and implementation of cyber norms.
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Levant: Deir Alla (Jordan)
This long term project in Jordan is at the basis of many specialists’ studies and has several off-shoot projects. The project, with its many approaches, is also a framework for much teaching in Levantine Archaeology at Leiden University, especially concerning fieldwork methods, artefact studies, research…
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About the programme
As a student in Security Studies you are a socially engaged critical thinker eager to study real-life security cases in an academic setting. You focus not just on the broad context of these issues but also on the role of government, institutions and media.
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WARN-D: developing an early warning system for depression in students
My ERC Starting Grant, funded with €1.5 million for 5 years as part of the Horizon 2020 research and innovation program, is focused on building the early warning system WARN-D to reliably forecast depression in young adults before it occurs. Why depression, and why prediction?