The mission of the Plant Science research programme is to contribute to the sustainable production of high quality crops, flowers and high-value bio-based products. This is realised by generating fundamental knowledge of basic biological processes related to development of plants and their interaction…

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In the master’s specialisation Molecular Genetics and Biotechnology at Leiden University students are trained by experts in the areas of molecular biology, microbiology, plant genetics, cellular imaging, animal disease models, and various –omics technologies and the corresponding bioinformatics.

Investigating neurobiological endophenotypes of Social Anxiety Disorder

Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.

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Are traces of fire use detectable in ancient hominin genomes?

This study analyses the prehistory of a northeastern Siberian population, the Sakha, from both a molecular-genetic and a linguistic perspective.

How does invasive hybridization affect threatened native species?

Promotor: Prof.dr. G.R. de Snoo

How do genetic and environmental factors make us vulnerable to depression?

Promotor: P.M. Brakefield

Description of Triple bottom line approach for risk-benefit analysis of genetically modified crops.

The applications of studying the early development of insects range from agriculture to material science.

The four possible segments A, T, C and G that link together to form DNA molecules, and with their ordering encode genetic information, are not only different in name, but also in their physical and chemical properties.

Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.

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Lecture

What is the population size/structure and distribution of tiger and leopard inside the Bardia National Park (BNP) compared with the population outside? What is the movement and home range and conflict pattern in time and space of tigers and leopards inside the BNP compared with outside? What constitutes…

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This thesis describes the genetic and prokaryotic diversity of giant barrel sponges.

In an innovative study, Radboudumc and LUMC jointly tested a candidate vaccine based on a genetically weakened malaria parasite. The results of this clinical trial, published in Science Translational Medicine, show that the vaccine is safe and elicits a defense response against a malaria infection.

Leiden University Medical Center (LUMC) has spent the past five years coordinating an international study of genetic mutations and breast cancer risks. The results will make it easier to determine which genes increase the risk of breast cancer and to what extent. The researchers published their results…

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It was already known that social anxiety disorder often affects more than one person in the same family. But research by PhD student Janna Marie Bas-Hoogendam has now shown that there are genetic brain characteristics that are associated with social anxiety. The PhD ceremony will take place on 14 Ja…

On 29 June the startup company Future Genomics Technologies will be launched. Its aim is to make DNA technology and research available for businesses faster. Future Genomics Technologies is a collaboration between DNA research laboratory BaseClear and Leiden University.

A collaboration between the IBL and LUMC has resulted in the discovery that the polymerase theta enzyme is essential for the integration of Agrobacterium T-DNA into the genome of plants. The finding means a break-through for the development of more efficient systems for targeted genome modification…

Promotor: J.M. Memelink

Promotor: E. Gittenberger, Co-promotor: B.W. Hoeksema

The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.

We aim to unravel the molecular mechanisms involved in the transformation of eukaryotic cells by Agrobacterium.

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Just like us, plants also produce growth hormones, and they also go through an ageing process. The study of the genes and mechanisms behind these processes is useful not only for crop breeding and agriculture, but also for medical research. That is the view held by Professor of Plant Developmental Genetics…

The role of language in self-regulation and social behavior in children with an extra X chromosome