In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…

This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with Boston Children’s Hospital in the USA.

Physics and Engineering Approaches to Biomedicine and Pharmacology

Vaccines are an extraordinary category of biopharmaceuticals. They are usually prophylactic and come in many types, from whole bacteria to peptides and nucleic acids. They are very cost effective and almost every human on the planet is vaccinated. The latter mandates that vaccines have to be extremely…

The master’s programme Statistics & Data Science provides students with a thorough introduction to the general philosophy and methodology of statistical modelling and data analysis. The programme has two specialisations: Data Science and Statistical Science.

Science, Leiden Academic Centre for Drug Research (LACDR)

The Netherlands Organisation for Scientific Research (NWO) has awarded Veni funding to seventeen researchers who recently obtained their PhD. This award offers promising young scientists the opportunity to develop their own ideas over a period of three years.

Freek Vonk and Mike Richardson, with many collaborators, have published two snake genomes in two parallel articles in the prestigious journal PNAS. Their new findings provide insight into the co-evolutionary arms race between predator and prey.

Why do opposites attract? According to Karin van der Tuin, researcher at Leiden University Medical Center (LUMC), it could be because of your DNA. The more you differ from one another, the better. She will be testing her ideas at the Lowlands festival Lowlands, where she will subject visitors to DNA…

Ben Wielstra and his team have received a ENW-M-1 grant. This grant of 354.000 euros is awarded by NWO, and will enable the researchers of the Institute of Biology Leiden and Naturalis to continue their evolutionary newt research.

Theoretical physicist Helmut Schiessel receives an NWO Projectruimte grant of 390,000 euro. He will use this budget to hire a postdoc and a PhD student to continue his research on flexibility of double stranded DNA.

A Memorandum of Understanding was signed by Professor Corinne Hofman of the Faculty of Archaeology, Leiden University and Professor Albert Feilzer from the Academic Centre for Dentistry (ACTA), University of Amsterdam and VU University, Amsterdam.

Cell-based medicinal products (CBMPs) belong to an innovative and heterogeneous group of medicines called advanced therapy medicinal products (ATMPs). The limited analytical toolbox for CBMP characterization and release testing is one of the reasons why CBMP development is so challenging.

We need to dispel the arrogant and misguided idea that modern humans are superior to earlier human species. It is thanks in part to all our predecessors such as Neanderthals that we are who we are today. This is what Marie Soressi, Professor of Hominin Diversity Archaeology, will argue in her inaugural…

Five Leiden researchers have been awarded a Consolidator Grant by the European Research Council (ERC). This grant of up to two million euros will enable them to continue and expand their scientific research.

Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…

In a festive and intimate award ceremony, plant scientist Omid Karami received the first edition of the Krijn Rietveld Memorial Innovation Award out of the hands of Wim Klop, Director of the Biotechnology Center at DSM. Several speakers spoke about Krijn Rietveld and why Karami deserves the prize that…

Researchers in Bilthoven, The Netherlands, have recently unraveled the defense against whooping cough bacteria in unprecedented detail. The outcome of the project, conducted at Intravacc (Institute for Translational Vaccinology) in Bilthoven, provides opportunities for a new approach in the development…

In an innovative study, Radboudumc and LUMC jointly tested a candidate vaccine based on a genetically weakened malaria parasite. The results of this clinical trial, published in Science Translational Medicine, show that the vaccine is safe and elicits a defense response against a malaria infection.

How does an embryonic stem cell decide if it becomes a heart cell or a kidney cell? That’s the question computational biologist Maria Mircea studied for her PhD research. She looked at the inside of individual cells to analyse how they change. This is what she discovered.

American pharmaceutical company Bristol Myers Squibb will be building a new (CAR-T) cell therapy facility in the Oegstgeest part of the Leiden Bio Science Park. The company will manufacture and develop CAR T-cell therapy for patients with blood cancer (leukaemia), for example.

He is said to be one of the greatest living statisticians. Bradley Efron gave a lecture in Marekerk and opened LUXs, the Leiden University Center for Statistical Science, the first university statistics centre in the Netherlands.

The ERC Council has awarded Starting Grants to five promising Leiden researchers. With an impressive three laureates, the Faculty of Social and Behavioural Sciences has done particularly well. The fourth grant goes to the LUMC and the fifth to the Faculty of Governance and Global Affairs.

According to the LUMC, patients experience 30% fewer serious side effects when medication doses are tailored to their DNA.

For her research on social-emotional regulation in children Michelle Achterberg on Wednesday, May 25 2022 received the Dutch Association of Developmental Psychology (VNOP) Dissertation Prize. With her PhD research, she mapped out which mechanisms play a role in social emotion regulation in childhood.…

The Lowlands pop festival is inviting scientists to make proposals for research at this year's festival (19 to 21 August).

Three Leiden researchers have been awarded a prestigious Vici grant, the Dutch Research Council (NWO) announced on Tuesday. Two of the researchers work at Leiden University and the third at the Leiden University Medical Center (LUMC).

The Open Day of Leiden University, on the 8th of this month, was a success again: 483 prospective students came to find out what Leiden has to offer. The Institute of Biology Leiden was also present.

The past decade, against the backdrop of a fragmented political landscape, has witnessed the greatest changes to the Netherlands since the aftermath of the Second World War. The labour market, the housing market, the energy market, the bank system, the pension system, the healthcare system, to name…

NWO has awarded a Vidi subsidy to a total of 89 young and innovative researchers. Leiden researchers have won twelve of these subsidies and three subsidies have gone to the LUMC. Each researcher will receive up to 800,000 euro to develop a particular research theme or to set up a research group.

Leiden scientists are the main applicants for five projects that have been awarded a Science Groot grant of up to 3 million euros in the Science Domain. In addition, several Leiden scientists are involved in other projects that have been awarded funding.

By analysing the metabolism using big data techniques, we can identify health risks at an earlier stage. Thomas Hankemeier, professor of Analytical Biosciences at the Leiden Academic Centre for Drug Research, explains how that works.

This year, NWO has awarded a Veni subsidy to 143 young researchers who have recently obtained their PhD. 17 of these researchers are at Leiden University and one works at the LUMC. The successful applicants will each receive 250,000 euro to develop their ideas and carry out research over a period of…

Mathematician Stéphanie van der Pas, winner of the C.J. Kok Jury Award for her PhD thesis in 2017, divides her time between research and education, and between pure mathematics and practical application.

Mathematical and computational analysis of the dynamics of polar transport of the plant hormone auxin.

With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…

Science, Leiden Academic Centre for Drug Research (LACDR)

Leiden University is involved in five new NWO Gravitation projects. Two relate to mental disorder and the remaining three to a healthy lifestyle, the combination of human and artificial intelligence, and the special relationship between plants and microbes.

To inhibit proteins that contribute to the growth of aggressive cancer cells, that’s the plan of Professor Bob van de Water and his team. They will receive over 700,000 euros from the KWF Dutch Cancer Society for their research. Researcher Maaike Vreeswijk and pathologist Danielle Cohen are affiliated…

Nine talented Leiden researchers have been awarded a Vidi subsidy by the Netherlands Organisation for Scientific Research (NWO). Vidis are intended for researchers with several years of research experience who want to set up or expand their own line of research.

Paco Barona Gomez is the newest associate professor at the Institute of Biology Leiden (IBL). The Mexican researcher is fascinated by the evolution of natural products: compounds made by microbes, but also plants and animals. ‘It’s like we investigate chemical dark matter.’

A new 5.7 million euro research project will ensure that lettuce will be more resistant to pathogens and climate effects and will grow better in new cultivation systems. Together with other Dutch researchers, Leiden biologists will map the characteristics and genetic information of 500 wild and cultivated…

Researchers, policymakers and funders have to take more account of the effect of sex and gender in scientific research. This is the view presented in an advice paper published by LERU, the League of European Research Universities. The lead author is Vice-Rector Simone Buitendijk.

The Dutch National Research Agenda announced today that it will provide 17 research projects with a total of 61 million euros in funding. Researchers from Leiden University or the Leiden University Medical Center are involved in five of the projects. All of the projects are interdisciplinary partnerships…

Bacteria that fluoresce green, blue or red may play a role in combatting resistance against antibiotics. Under the motto of 'Say yes to stress', thirteen ambitious Leiden students are aiming to amass 9,000 euros to carry out their research project.

Lecture

It might be possible to prevent atherosclerosis by changing the appearance of macrophages, cells of the immune system that for example digest foreign substances. In her PhD dissertation, Baoyan Ren examined several ways to do so.

We use zebrafish as a model organism to study human development and disease as well as animal welfare and environmental impact.