1910 search results for “g protein-coupled receptor” in the Public website
-
The Use of Activity-Based Protein Profiling to Study Proteasome Biology
PhD Defence
-
Applications for activity-based probes in biomedical research on glycosidases
Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.
-
Unwinding a hank of yarn: how do cellular machines unfold misfolded proteins?
Protein chains typically fold to function. Folding is a complex process and if done correctly leads to a unique functional fold topology for a given protein chain. Other topologies are also possible but are often non-functional or toxic. These misfolded proteins are then unfolded and subsequently refolded…
-
Student team hopes to heal skin with squid protein
Eleven ambitious Leiden students hope to heal burns with a special substance from squid teeth. They are taking part in the international iGEM competition. They need to raise almost 10,000 euros to fund their project this summer.
-
The RNA-binding protein Quaking in vascular health and disease
PhD Defence
-
Sticky & Dirty Proteins
PhD Defence
-
Decomposing tears in order to detect Dry Eye Disease
By measuring proteins in tears, ophthalmologists can more easily diagnose dry eyes (Dry Eye Disease). Peter Raus, a Belgian ophthalmologist and PhD student at the Institute of Biology Leiden, developed a new method for protein determination in tear fluid. The technique is also promising for the early…
-
Biological and Soft Matter Physics
Research groups in the Biological & Soft Matter Programme unravel mechanisms in biological processes and develop novel bio-inspired soft materials.
-
New cellular imaging paves way for cancer treatment
A new technique using fluorescent imaging to track the actions of enzymes might aid drug design for new anti-cancer, inflammation and kidney disease treatments. Researchers at the University of York and Leiden University have published these findings in Nature Chemical Biology.
-
applications of paramagnetic NMR spectroscopy for protein research
PhD Defence
-
The Huntingtin protein in Huntington disease
PhD Defence
-
Mass spectrometry based protein profiling
PhD Defence
-
Chemical tools to study the cannabinoid receptor type 2
PhD Defence
-
Tailoring adjuvant therapy for hormone receptor-positive early breast cancer
PhD Defence
-
Pharmaceutical Aspects of Subvisible Particles in Protein Formulatins
PhD Defence
-
Mass spectrometry based protein profiling
PhD Defence
-
Same-sex couples in Europe: more rights in more countries
Launch database
-
Jelle van Buuren and Dennis Broeders on 5G: Technological Dangers and European Chances
The 4G network will soon be replaced by 5G. 5G will enable users to set up faster and more reliable data links as well as better privacy protections. For intelligence agencies, however, the upgrade in data protections will create huge problems.
-
Advances in GPCR Modeling Evaluated by the GPCR Dock 2013 Assessment: Meeting New Challenges
Source: Structure , Volume 22, Issue 8, pp. 1120-1139 (2014)
-
Maria van der SchaarFaculty of Humanities
-
Microbial Chemotaxis
In order to gain insight into the structure and function of the molecular complexes involved in chemotaxis, we use electron cryotomography (ECT). This technique allows us to directly study microbes in their native state at resolutions capable of visualizing individual proteins.
-
to insurmountability: Novel avenues to better target CC Chemokine receptors
PhD Defence
-
Research Grant for tuning into photosynthesis
Biophysicist Anjali Pandit has been awarded a FOM 'Projectruimte' research grant for her proposal ‘Tuning into the photosynthetic membrane with atomistic precision’.
-
Chemical Biology Lecture: Chemical Protein Synthesis - Providing Tailor-Made Proteins for Biology and Medicine
Lecture
-
Regulation of Target Proteins by Small Ubiquitin-like Modifiers
PhD Defence
-
in zebrafish caudal fin regeneration: differential requirement for protein-tyrosine phosphatases
PhD Defence
-
Protein Surface Recognition Using Designed Molecules
Lecture
-
Innovation and Tradition: The Odd Couple
Debate
-
FRESH Lecture: CO2 splitting by inductively-coupled hybrid plasma catalysis and Boudouard reactions
Lecture
-
Biology Lecture: The power of chemoselectivity - Functional peptide and protein-conjugates for proteomic and pharmaceutical research
Lecture
-
Quantitative live cell imaging of glucocorticoid receptor dynamics in the nucleus
PhD Defence
-
Toll-like receptor signaling in the innate immune system of zebrafish larvae
PhD Defence
-
Design, synthesis and application of paramagnetic probes for protein structure studies
PhD Defence
-
Controlling growth and morphogenesis of the industrial enzyme producer Streptomyces lividans
Promotor: Prof.dr. G.P. van Wezel, Co-Promotor: E. Vijgenboom
-
The Effects of Breast Cancer Therapy on Estrogen Receptor Signaling Throughout the Body
PhD Defence
-
Anti-Carbamylated protein antibodies in Rheumatoid Arthritis
PhD Defence
-
Jaap de Hoop Scheffer on the position of Europe during the G20 summit in Osaka
Jaap de Hoop Scheffer, Professor International Relations and Diplomatic Practice at the Institute of Security and Global Affairs at Leiden University spoke to Belgian (Flemish) news magazine Knack about the position of Europe in relation to the United States and China. ‘Europe has to be careful to avoid…
-
Activity-based Protein Profiling of the Diacylglycerol Lipases
PhD Defence
-
Functional analysis of Agrobacterium tumefaciens virulence protein VirD5
PhD Defence
-
Activity-based protein profiling in drug discovery
PhD Defence
-
Chemical Biology Lecture: Carbohydrate-binding Proteins as Targets for Anti-Infectives and Diagnostics
Lecture
-
G20 leaders please promote regional cooperation in the implementation of international standards, including BEPS
Irma Johanna Mosquera Valderrama, principal investigator of the ERC GLOBTAXGOV project and Associate Professor of Tax Law has participated in the T20 task force on Trade, Investment and Tax Cooperation under the Argentinian Presidency. As a member of the task force, she has contributed to the policy…
-
Feodor-Lynen research fellowship for Bela Bode
Dr Bela Bode receives a Feodor Lynen research fellowship for postdoctoral researchers by the Alexander von Humboldt-Foundation for development of new methods for signal enhancement in solid state NMR. He aims to create a specific analytical tool for surface studies and research on membranes and membrane…
-
Two Leiden astronomers awarded with prestigious IAU PhD Prize
Two Leiden astronomers will receive the prestigious IAU PhD Prize. Both Jorryt Mathee and Niels Ligterink of the Leiden Observatory won a prize. Scientific director Huub Röttgering: We are proud that this year two of our PhD students receive an IAU prize for the best thesis in their field of researc…
-
Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
PhD Defence
-
Cannabinoid receptor 2 agonists on their way to clinics – How industrial drug discovery and academic research can cross-fertilize each other
Lecture, Van Leeuwenhoek Lecture on BioScience
-
disease mechanisms in neurodegeneration: solid-state NMR studies of protein aggregation and mitochondrial lipid oxidation
Lecture
-
The characterization of anti-Carbamylated protein antibodies in rheumatic diseases
PhD Defence
-
Visualization of effector protein translocation from agrobacterium into host cells
PhD Defence
-
Parkinson’s Protein α-Synuclein: Membrane Interactions and Fibril Structure
PhD Defence