PhD candidate Vincent Walstra reflects on alternative social interactions and mutual aid in the city of Rotterdam during the first wave of the Covid-19 pandemic.

How can the transport of molecules in living cells help to target medicines at exactly the right place?

Establishing human induced pluripotent stem cell (iPSC) CRISPR-Cas9-based fluorescent reporter cell lines for NF-kB signalling. We will use this to enable studying the dynamic activation and downstream signalling of Toll-like receptor and cytokine signalling in iPSC-derived differentiated cells in a…

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

SLAVES TO THE SYSTEM: Locating Responsibility for Forced Expatriate Labour Practices by the Democratic People’s Republic of Korea (DPRK)

Think tanks have proliferated in most Western democracies over the past three decades and are often considered to be increasingly important actors in public policy. Still, their precise contribution to public policy remains contested.

Even though more than 4000 extra-solar planets are known today, only a small fraction of these has been captured in an image. To better understand the planet formation mechanisms in solar-like environments we started the Young Suns Exoplanet Survey (YSES).

On 14 November 2019, Luis Fiallos Pazmino defended his thesis 'Legal Perspectives on the Cross Border Operations of Unmanned Aircraft Systems'. The doctoral research was supervised by Prof. P.M.J. Mendes de Leon and Prof. E.C.P.D.C. De Brabandere.

HomininSpace is an agent based modelling and simulation system in which fluctuating carrying capacity is the key attractor for hominin dispersal. A parameterized and spatially explicit reconstructed palaeo-environment models available energy in the form of secondary biomass using reconstructed climate…

A network combining 9 academic research groups and 4 collaborating industrial companies will train the next generation of PhD students and post-doctoral researchers, in developing and applying novel experimental and theoretical methods in the NMR spectroscopy of systems containing paramagnetic metals.…

Legal protection. What do those involved in youth care and child protection understand by this concept? And what needs to change to improve legal protection? This question was explored by researchers from Leiden University’s Department of Child Law. Their research fits with the government’s ambition…

Using artificial intelligence is more complicated for the government than for companies. Bram Klievink, Professor of Public Administration, aims to identify the problems and find solutions.

What is Interaction between Legal Systems (ILS) and what does it entail as research profile area at Leiden Law School? More on this at the kick-off event of ILS 2.0. This will take place on Wednesday 26 October 15.00 – 17.00 in the Grotiuszaal (A051 KOG). The afternoon will be closed with drinks at…

During the Dutch famine of 1944–45, people were much more creative in finding food than we thought. Biology student Tom Vorstenbosch discovered that people did not only eat flower bulbs at that time, but also radish leaves and wild plants such as sorrel and chickweed.

What invertebrates are available to feed nestlings in an agricultural landscape of varied complexity?

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

From descriptive to physiological models that can predict oral absorption and elimination of CYP3A substrates across the pediatric age range.

The complex pathophysiology of immuno-dermatological disorders is multifactorial, including environmental, skin microbiome, (epi)genetic and immune dysregulation conditions. This project primarily focuses on the orphan disease mycosis fungoides, a subtype of cutaneous T-cell lymphoma. The current pathophysiological…

Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?

Homicide engenders broad moral concerns in society, and its aftermath can be understood as a barometer for criminal justice policy. Of all homicides committed, however, only some lead to arrest, to prosecution and ultimately to conviction in court.

This paper describes two synthetic lipid models designed to replace human stratum corneum (SC) in studies of the impact of volatile organic chemicals on the molecular organization of the skin barrier lipids.

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

The potential of liposomal cancer vaccines

If you study law, you won’t necessarily end up striding round a law firm in tailor-made suits. Alumnus Harrie Schoffelen certainly hasn’t: he made the conscious decision to follow another path in life. Together with his fiancée he runs a successful food truck on the tropical island of Bonaire. ‘Return…

Handbook of Signal Processing Systems is organized in four parts. The first part motivates representative applications that drive and apply state-of-the art methods for design and implementation of signal processing systems; the second part discusses architectures for implementing these applications;…

Lodewijk Petram, author of the book 'The World's First Stock Exchange', discussed the rise of the Amsterdam stock exchange in the 17th century in the ninth Hazelhoff Guest Lecture.

Promotor: Prof.dr. L.J. Slikkerveer

Masses of hamburgers, steaks, cheese and a lot of eggs: Americans love their animal products. But researcher Oliver Taherzadeh discovered that only a relatively small group of high-volume consumers need to modify their diet to achieve an enormous environmental gain.

Promotor: Prof.dr. M. Danhof

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

What is the origin of solar systems?

Indonesia is experiencing various environmental challenges related to its fast economic growth. Therefore, it is necessary to have measurable and applicable indicators to obtain accurate data and information regarding the costs of adverse environmental impacts arising from economic activities to support…

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.

A convolutional neural network (CNN) is a biologically inspired algorithm, highly capable at processing images and videos.

Ever wondered how big the food waste problem really is?

Research by Leiden University, LUMC and the Public Health Department (GGD Haaglanden) in The Hague has shown that over a quarter of the families in the city who took part in the survey experience some form of food insecurity. Some families have too little money to make a healthy meal or are worried…

The languages of the Mbam-et-Inoubou District of the Centre Region of Cameroon have a unique position in Bantu linguistics. Being in between