Promotor: A. Doelman, Co-promotores: P.J.A. van Heijster; A. Zagaris

According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).

Students in Leiden are entitled to good teaching and good supervision. For their part, there are some conditions they have to meet to ensure that they complete their studies within the time allotted.

The research of this programme is centered around dynamical systems, functional analysis, and their interplay.

Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon

Arnold van der Valk on Food Council MRA.

The master's specialisation Bioinformatics at Leiden University focuses on research, development and application of computational tools and approaches for expanding the use of biological, medical, behavioral and health data.

Promotor: Arjen Doelman, Co-promotor: Vivi Rottschäfer

The two-years master’s specialisation System Biomedicine and Pharmacology at Leiden university focuses on predicting drug response with computational modelling, developing individualised therapies, and developing innovative analytical tools for personalised health strategies.

This thesis provides explicit expressions for the density functions of absolutely continuous invariant measures for general families of interval maps, that include random maps and infinite measure transformations, not necessarily number systems.

Interaction between Legal Systems acknowledges that law-making and law enforcement are increasingly taking place on various levels: in a global context, in EU context, on a national level and in a private law framework. These levels influence each other, sometimes directly, on the basis of a hierarchical…

In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.

How do balanced lethal systems originate and persist in nature?

The research groups within the biological, soft and complex systems research area study the physics of a broad range of biological and soft materials. This spans both experimental and theoretical research.

The ambition of the Medical Systems Biophysics and Bioengineering group led by Alireza Mashaghi is to develop and use physics and engineering concepts and tools for pathophysiology, diagnostics and therapy.

In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.

What did our distant ancestors eat and how did they prepare their food? For the length of a month, experimental archaeologist Diederik Pomstra subjects himself to a rigorous palaeodiet. He is vlogging about his experiences to reach a non-academic audience.

This book explores the boundaries of the category of gender and their theoretical significance within the framework of Canonical Typology.

Grammatical gender is famously the most puzzling of the grammatical categories. We have a solid typology of gender systems, yet exciting and unexpected patterns keep turning up which defy easy classification and straightforward analysis. Some of these question, stretch or threaten to cross the outer…

How can we organize the food system in the Amsterdam Metropolitan Region in a more sustainable and democratic way? Prof. Cristina Grasseni gave a presentation of her work at the Food Council Metropolitan Region Amsterdam.

Duality, stochastic processes

Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.

Between the 30th of January and the 2nd of February 2020 around 250 people took part in the II Polish Food Sovereignty Forum.

Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen

Advisory Board member Colin Sage shares insights about the Food Citizens? project.

This interdisciplinary research project explores several adaptive machine learning methods which can give insight into the interaction between human and machine. The ultimate goal is open and natural communication between humans and AI that should result in mutual trust, cooperation and coordination…

At Leiden University we believe it is important that you receive the right kind of support in your choice of study and while you study. This is why we use what we call the ‘Leiden study system’ to help you make a success of your study from start to finish.

Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Promotor: S.M. Verduyn Lunel, Co-promotoren: M.F.E. de Jeu, S.D. Silvestrov

Research into research improves the academic system. CWTS studies and evaluates the academic system in various ways. One way is to provide information on the productivity and impact of academics by documenting how many publications they or their universities produce and how often these publications…

Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski

Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang

In this article, Marco Cinelli, assistant professor at Leiden University College The Hague, examines proper and improper uses of Multiple Criteria Decision Analysis (MCDA) methods in energy systems analysis.

In January 2020, the team took a break from their respective field sites and travelled back to Leiden to take stock of their research progress and to host its third Advisory Board meeting at their home institution, the Institute of Cultural Anthropology and Development Sociology of Leiden Universit…

An important hormone excreting gland in the human body is the pituitary

This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.

Promotor: Prof.dr. S.F. Portegies Zwart, Co-promotor: D.C. Heggie

Systems pharmacology aims to apply techniques from systems biology to pharmacological models.

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…

Dishoeck

Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher

A plant-based diet could improve the resilience of our food system. Moving to such a diet in the European Union (EU) and United Kingdom (UK) alone could replace almost all the production losses from Russia and Ukraine. That’s what an international team of researchers conclude in Nature Food. Leiden…

How are carbohydrates processed by the immune system? Can carbohydrates be used to trigger T-cells against other conjugated antigens? Can they be used as adjuvants?

High-throughput holistic preclinical screens are increasingly used in drug discovery, to assess both drug efficacy and drug safety.

On the first weekend of June a plot of land in Lutkemeerpolder, West Amsterdam, was occupied in order to host the Food Autonomy Festival. The event was organized in solidarity with local farms to protest against the development of Schiphol airport-oriented business park. Two of our PhD's, Maria Vasile…

Lecture

Promotor: S.M. Verduyn Lunel

Science, Institute of Biology Leiden (IBL)