With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…

Promotor: M. Ubbink, Co-promotor: G. Siegal

This research intents to redefine the limits of the electric guitar.

One of the holy grails of drug research is to be able to assess the safety of chemicals and pharmaceuticals without using laboratory animals. Researchers from Leiden University, among others, now receive a grant from the National Science Agenda to pursue that goal.

This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…

Thomas Hansen is our Leiden Institute of Chemistry's nominee for the C.J. Kok Jury Award 2020.

Operating on tsunami victims, coordinating emergency aid during a civil war and the croaking of frogs in the surgery: Menno Swier worked as a doctor of tropical medicine in Papua New Guinea and Indonesia. He is now a GP on Terschelling and here too there is never a dull moment.

We focus on natural products research, traditional medicine, ethnobotany and phytochemistry.

Chemists developed a new graphene-transferring method which makes use of cyclohexane. This new method leaves less impurities on graphene, is easier to handle than current methods and is widely applicable in graphene research. The publication will be on the cover of the journal ACS Central Science late…

The Leiden Observatory has appointed a new professor. Selena Viti will hold a chair in Molecular Astrophysics. Viti will build a research group that combines different research techniques to unravel the secrets of local and external galaxies. ‘My main ambition is to change the way scientists interpret…

Playing the piano with your forearm, plucking the strings, sawing through the piano: pianist Luk Vaes's doctoral dissertation covers all the techniques of play for which a piano is NOT designed. His defence ceremony will consist of three concerts and a public defence. 'Musicians were using the interior…

Tackling key challenges of Chemical Biology and Medicinal Chemistry to aid drug discovery is one of the focus areas of Leiden University. To this end, the Leiden Early Drug Discovery & Development network (LED3) was established by the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden…

Gerard van Westen has been appointed full Professor or Artificial Intelligence and Medicinal Chemistry. This chair has been jointly created by the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institute of Chemistry (LIC) as part of SAILS, the university stimulus program in Artificial…

Authoritative and cutting-edge, Bacterial Chromatin: Methods and Protocols aims to be useful as an up-to-date reference work for scholars in the bacterial chromatin field, those entering the field from adjacent research fields, and scientists in the eukaryotic chromatin field.

Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity.

Promotor: Prof.dr. H.L.V. Linnartz

This thesis revolves around the electronic spectroscopy of molecules in the laboratory and the search for the carriers of the diffuse interstellar bands (DIBs).

Mathematical and computational analysis of the dynamics of polar transport of the plant hormone auxin.

Education in (Chinese) Medicinal Plants associated to the Hortus botanicus in Leiden - Which Traditional Chinese Medicinal plants can be grown in the Hortus? - Establishing of a database which Chinese medical plants are available in Dutch Botanical Gardens - Data validation (correct identification,…

The GMP Facility facilitates development and production of Advanced Therapy Medicinal Products (ATMPs) and chemical (peptide) synthesis.

At Molecular Physiology we teach the following courses within the Leiden Institute of Chemistry's Chemistry and Life Science and Technology programmes.

Personalised healthcare could be the answer to insufficient treatment of chronically ill people. Therefore, PhD Junzeng Fu tries to predict the response of a patient to a drug. Strikingly, she combines western medicine with Chinese medicine diagnosis. Promotion Tuesday 21 February.

Promotor: Prof.dr. E. Smets, Dr. M. Stech

Promotor: Prof.dr. E.F. Smets

Laura Heitman is awarded the 2018 EFMC runner-up prize for a Young Medicinal Chemist in Academia

Source: PLoS ONE, Volume 10, Issue 3 (2015)

The Quantitative Pharmacology group headed by Coen van Hasselt focusses on the application of state-of-the-art quantitative pharmacometrics and systems pharmacology modeling combined with translational experimental models to develop personalized treatment strategies for antibiotics and to combat antimicrobial…

Professors Simcha Jong (Leiden University) and Rifat Atun (Harvard University) convened an exploratory seminar to discuss challenges for health systems in realising the potential of precision medicine at Harvard University’s Radcliffe Institute for Advanced Studies in Cambridge, MA on 17 April 2017.

The Metabolomics Facility of the University of Leiden has brought together two research groups from the Faculty of Science that are well-known for their expertise in two different fields: the Biomedical Metabolomics Facility Leiden, experts in clinical metabolomics and the Natural Products Laboratory,…

Composer Paul Craenen (1972) is actually a pianist, but as part of his PhD ceremony, he performed a composition on PVC pipes. Craenen studies the position and role of the body in music. ‘I am interested in what precedes the resulting sound’.

This thesis investigated how microphones and loudspeakers could become musical instruments.

Spirits play a important role in post-colonial and minority literature as a means of processing black pages from history, according to literary scientist Chia-Sui Lee. PhD defence 11 January.

Microbial Sciences' contribution to the Evolution & Biodiversity research theme focuses on understanding how bacteria sense and respond to their environment, and how bacterial diversity and evolution is influenced by cooperative and antagonistic interactions taking place between microbes.

Cell-based medicinal products (CBMPs) belong to an innovative and heterogeneous group of medicines called advanced therapy medicinal products (ATMPs). The limited analytical toolbox for CBMP characterization and release testing is one of the reasons why CBMP development is so challenging.

At the International Online Conference 'Fair Medicine and Artificial Intelligence' organised by the University of Tübingen (Germany), Hadassah Drukarch, junior researcher at eLaw, gave a presentation on how current algorithmic-based systems may reinforce biases in healthcare. This topic forms part of…

Promotor: Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar

Commercial enterprises who want to make use of the expertise and facilities are referred to LAB , the commercial unit responsible for specialized laboratory work.

Some examples of AI-research done at Leiden.