Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…

With an ageing population it is becoming increasingly important to find means to repair cells, tissue and organs through regenerative medicine.

Experimentalism has emerged as a prominent approach for addressing environmental problems. Christopher Ansell (Berkeley) and Martin Bartenberger (Leiden University) survey the diversity of experimentation methods, identifying their strengths and weaknesses, and suggesting possibilities for fruitfully…

Chemistry is all around us: from nutrition and smartphones to medicine. The field is developing rapidly, as the world population continues to grow and resources become scarce. MST will educate you on the basics of working towards a clean and healthy world.

Assessing and implementing new diagnostics strategies for stratifying patients

The Faculty of Medicine

In this research group, headed by Laura Heitman, novel receptor concepts in drug discovery are studied, aiming to increase the effectivity of medicines. Many drugs act via so-called G protein-coupled receptors (GPCRs) and therefore our research is mainly focused on understanding and improving drug-receptor…

How do we process language and speech? How do we integrate information at different levels – intonation, sentence structure, meaning, tone, words, sounds - and how does information at one level interact with information at another level?

The project’s main aim was to build a reconstruction of a prehistoric house plan, without using any metal tools. How effective are tools made of stone, flint, bone, antler and wood? What are the constraints imposed by the various building materials? How much labour do we need and how much knowledge…

How do you fit two meters of DNA in a tiny compartment and at the same time are able to access the right parts of it at the right times?

Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…

Psycholinguistic research

Getting personal

In the master’s specialisation Molecular Genetics and Biotechnology at Leiden University students are trained by experts in the areas of molecular biology, microbiology, plant genetics, cellular imaging, animal disease models, and various –omics technologies and the corresponding bioinformatics.

Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros

We are very happy to welcome you to spend a semester or year studying or doing an internship with us at the Leiden University Medical Center. Here you will find information on your course timetables and registration.

The research programme Formal Theoretical and Experimental Linguistics brings together LUCL researchers who focus mainly on formal theoretical and experimental linguistics.

Can we establish a new quality control system for herbal medicines that is based on bioactivity rather than a few abundant chemicals?

Leiden University offers a unique interdisciplinary joint-degree Master programme in technical medicine together with TU Delft, Erasmus University Rotterdam and their academic medical centers.

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

The mission in this research group, headed by Ad IJzerman, is to design and synthesize novel and better ligands for drug targets. Drug discovery is a lengthy but inspiring adventure. It is often an interplay between academic institutes and pharmaceutical industry, in which scientists at university develop…

More and more medicines are becoming available that target a tumour’s specific traits. The use of chemotherapy is continually undergoing improvement.

The research presented in this thesis makes use of small molecules (as H2 , D2 and O2 ) on well-defined single crystal surfaces (flat Pt(111), flat Cu(211) and curved Pt(111)) to elucidate the role of surface structure and degrees of freedom in the reactant in specific surface reactions.

Science, Leiden Academic Centre for Drug Research (LACDR)

The master's specialisation Molecular, Cellular and Organismal Biology at Leiden University examines the molecular mechanisms underlying health and disease and how cells and organisms adapt to environmental factors.

Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.

Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz

The experimental approach of science applied to artistic research

Promotor: Prof.dr. G.J. Kroes

In October 2014 a new publication on artistic research has been launched. The book is called Artistic Experimentation in Music. An Anthology, edited by Darla Crispin and Bob Gilmore, and published by Leuven University Press.

How can the transport of molecules in living cells help to target medicines at exactly the right place?

Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert

Humanities, Centre for Linguistics

This Master programme will equip you with the necessary competences to play a key role in the emerging field of transfusion medicine. Its current concept includes both transfusion of blood components and hematopoietic transplants, cellular and tissue therapy and immunotherapy. Areas that are integrated…

Science, Institute of Biology Leiden (IBL)

With the energy transition toward a renewable energy supply and a CO2-neutral economy, electrification of the energy system is rising in importance, which leads to the challenge of long-term storage of renewable electricity.

This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.

Can the pink-pigmented microbe Methylobacterium extorquens be genetically engineered to convert the sustainable raw material methanol into antibiotics?

Promotor: Prof.dr. H.V.J. Linnartz, Co-Promotores: S. Ioppolo, H.M. Cuppen

Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.

Worldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies.

Science, Leiden Academic Centre for Drug Research (LACDR)

Adverse drug reactions (ADRs) remain one of the major reasons for patient mortality and (early) drug withdrawal. Currently, different in vivo and in vitro models are used to assess the toxic potential of drugs in the pre-clinical phase. Unfortunately, the predictive value of this model does not fit…

Science, Leiden Academic Centre for Drug Research (LACDR)

What are the biological effects of Chinese herbal medicine in regulation of cancer cell metastasis?