Promotor: Prof.dr. I.A.G. Snellen, C.U. Keller

With the dramatic growth of the image data on the web, there is an increasing demand of the algorithms capable of understanding the visual information automatically.

The programme group Research Methods and Statistics has a wide expertise in research methodology. The group offers methodological support in many projects in the field of education and child studies, and develops its own methodological research projects based on questions arising from this field.

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

Promotor: M. de Jong, Co-Promotor: Samtleben

Aim of the proposal is to develop lugdunomycin into a drug candidate able to treat infectious diseases caused by multi-drug resistant pathogens.

Detection of cerebral beta-amyloid (Abeta) by targeted contrast agents remains of great interest to aid the in vivo diagnosis of Alzheimer's disease (AD). Bis-styrylbenzenes have been previously reported as potential Abeta imaging agents.

Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel

Our cantilevers have a low intrinsic damping rate: this enables us to measure with low noise, since damping is proportionate to noise. However, when the magnet is close to the surface of a sample we want to study, we measure a much higher effective damping rate. This is caused by magnetic interaction…

This article provides an in‐depth assessment of lone actor terrorists’ attack planning and preparation.

Sarah Giest and Annemarie Samuels, both Assistant Professors at Leiden University, researched the quality and coverage of the data being collected for policiymakers to be used, specifically pertaining to minority groups.

Promotor: Prof.dr. T. Hankemeier, Co-Promotor: R.J. Vreeken

This volume edited by Jan Lucassen and Leo Lucassen aims to quantify and qualify cross-cultural global migrations and was published in the series 'Studies in Global Migration History'.

The mechanism of the electrochemical reduction of dioxygen by a mononuclear pyridylalkylamine copper complex was investigated (see picture). It was shown that in neutral aqueous solution dioxygen undergoes stepwise reduction, wherein hydrogen peroxide plays a key role. The rate constants determined…

The main focus of this thesis is the behaviour of two-dimensional materials, namely (anti)-ferromagnetic materials in the first two chapters, which show topological phases, and energetic square ice in the third and fourth chapter.

Promotor: Jelle S. Kaastra Co-promotor: Jelle de Plaa

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

And its application in deciphering hominin diets in palaeolithic eurasia

Prehistoric burial mounds are still ubiquitous in the Northwest European landscape, but not much is known on the landscape they were part of, nor on what preceded them.

Optical projection tomography (OPT) is a tomographic 3D imaging technique used for specimens in the millimetre scale.

Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae

Promotor: M.A.G.J. Orrit

Brain development in children with an extra X chromosome as compared to children with autism: evidence from MRI

The overall objective of this project is to identify novel drug candidates that are capable of slowing down the progression of neurodegeneration in the subset of Parkinson’s disease (PD) patients with overt mitochondrial dysfunction. Multimodal phenotypic characterisation of cohorts of monogenic PD…

Promotor: V. Vitelli, Co-promotor: J. Paulose

All doctoral dissertations are checked for plagiarism before they are submitted to the doctorate committee.

Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.

Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.

This thesis examines the link between simple molecules and the underlying structure and chemistry within protoplanetary disks - the birthplaces of planets.

This thesis focuses on protoplanetary disks: flattened structures of gas and dust around young stars in which planets are expected to form and grow.

Lecture

The CMCB brings together microbial cell biology expertise in Leiden. It aims at optimal resonance between the groups and maximal exploitation of the available infrastructure and to develop innovative cross-boundary technology platforms.

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

Citizen science has recently become a widely used term, but what does it mean exactly? How does citizen science compare to crowdsourcing? And where does community archaeology stand in this discussion?

CML-IA is a database that contains characterisation factors for life cycle impact assessment (LCIA) and is easily read by the CMLCA software program.

The research master's specialisation Cognitive Neuroscience consists of five main parts: the general courses, the specialisation-specific courses, the elective courses, a research internship and a thesis.

Análisis y Conversión del Vocabulario de fray Francisco de Alvarado (1593)

This study’s main aim is to test whether children’s learning behaviour explains why they do not benefit from a literate environment.

In CCLS several subgroups have formed, below you can find an overview of these groups with the names of the leading researchers and a short outline of the project.

Does an Emotional Working Memory Training show a beneficial transfer effect on emotion regulation (reappraisal) capacities in patients with Borderline Personality Disorder?

The Faculty of Science grants two C.J. Kok awards each year: the C.J. Kok Public Award, also known as the award for the ‘Discoverer of the Year’, and the C.J. Kok Jury Award, the award for the best PhD thesis from the past year. All institutes within the faculty are given the opportunity to nominate…

Plants, algae and cyanobacteria have the amazing capacity to perform delicate photophysical and photochemical processes of light capture, excitation transfer, charge separation and catalysis in fluctuating living environments. As a consequence, photosynthetic proteins and membranes form dynamic architectures.…

The main purpose of DNAmarkerpoint is to better understand the ecology, evolution and biodiversity through the study of ancient- and modern DNA.

Knowledge and culture subproject 1: "Music Cognition" of Leiden University Centre for Linguistics

MRFM combines the principles of magnetic resonance and atomic force microscopy.

This project aims to improve understanding of, and responses to, the phenomenon of lone actors through analysis of comprehensive data on cases from across Europe.

Metabolomicshas emerged as an important discipline to study molecular and cellular processes in living cells and organisms with the ultimate aim to obtain an answer to a given biological/clinical question.

We explore the possibilities to combine magnetic resonance techniques with atomic force microscopy together in a single microscope: the MRI-AFM, also called Magnetic Resonance Force Microscopy (MRFM).

If researchers make their data FAIR, computers can link large quantities of data and identify patterns, thus greatly accelerating the process of arriving at new insights. In Leiden, the birthplace of ‘FAIR data’, Professor Barend Mons explains the meaning of this term.

Researchers of the National University of Singapore and Leiden University have discovered that chimpanzees and bonobos share the contrasting colour pattern seen in human eyes, which makes it easy for them to detect the direction of someone’s gaze from a distance.