What is the optimal investment policy according to which a firm adapts its capacity in a competitive market?

Chromatin is an ubiquitous protein-DNA complex that forms the structural basis of DNA condensation in all eukaryotic organisms.

Rossi

In the early universe, the dynamics of the Higgs field can give rise to many interesting phenomena.

This research group is interested in the physics of living cells, especially their cytoskeleton dynamics under defined external stimuli.

Developing methodes to understand the evolution of patches in natural ecosystems

Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.

Schemas are knowledge structures that allow us to make efficient judgments about the world without the cost of memorizing every detail of previous experiences. It has long been known that schemas can enhance long-term memory for related information.

How can lasers control the growth of new blood vessels?

What is the effect of light at night on plant phenology and physiology, and how does this affect plant interactions with other species?

Throughout all domains of life, from bacteria and archaea to eukaryotes, genomes adopt well-organized three-dimensional structures that can change in space and time to accommodate preferred transcriptional programs for environmental adaptation, the maintenance of cellular identity and differentiation…

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

Science, Institute of Environmental Sciences (CML)

The intracluster medium (ICM) is a hot, tenuous and X-ray emitting gas that pervades galaxy clusters.

Promotor: Prof.dr. G.J. Kroes

Metal-containing molecules combine geometrical features and a reactivity that are inherently different from that of organic molecules. My research focuses on light-activatable metal-based anticancer drugs and metal-functionalized liposomes. Light is a very selective way to activate photosensitive drugs…

This dissertation shows that dialogical logic constitutes a powerful and flexible general framework for the development and study of various logical formalisms and combinations thereof.

Promotor: S.M. Verduyn Lunel, Co-promotor: O. van Gaans

Promotor: Prof.dr. V. Icke, Co-Promotor: T.I. Madura

Polycyclic aromatic hydrocarbons (PAHs) are the most abundant class of organic compounds in space. The PAH field evolves from the constant interaction between experimentalists, theorists, modellers and observers. While laboratory research and quantum chemical calculations together set up the molecular…

Can light-activatable ruthenium compounds be used as a more selective anticancer treatment?

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn, Co-promotor: Dr. M.J.M. Schaaf

This functional genomics project aims at understanding the biology of the underlying mycelium differentiation and autolysis processes in much more detail.

An overview of the research at the Biologics Formulation group

This project addresses the occurrence of political and ideological biased crimes in light of the recent migration influx in European countries.

Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.

In this thesis, time-lapse fluorescent microscopy plays a pivotal role in investigating functional materials within living cells as well as the migratory behaviour of neural progenitor cells.

Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)

Promotor: Prof.dr. T. Schmidt, Co-Promotor: Dr. ir. S.J.T. van Noort

How do nanoparticles bioaccumulate and biodistribute in organisms?

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

What are the principles of genome folding and dynamics in bacteria?

Isis on the Nile. Egyptian gods in Hellenistic and Roman Egypt

In this thesis, we study travelling waves in stochastic reaction-diffusion equations. We extend techniques from the deterministic theory for travelling waves to apply to the stochastic version, which allows us to compute the stochastic wave speed and shape, and draw conclusions on the stability of the…

The work presented in this thesis addresses the role of the locus coeruleus (LC) - norepinephrine (NE) system in various aspects of human cognition, and the modulation of brain state.

For present purposes, it is important to distinguish between an early period of settlement, about 6800-6200 BC, and a late period, about 6200-5800 BC, at Tell Sabi Abyad.

Promotores: Prof.dr. J. Aarts, Prof.dr. J.M. van Ruitenbeek

How citizens and professionals are the key to successful collaboration in the delivery of public services. How do individual characteristics of citizens and professionals influence citizen-professional collaboration in the co-production of public services?

In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.

The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…

Promotor: E. Bouwman, Co-promotor: S. Bonnet

Promotor: Prof.dr. E.F. van Dishoeck, Prof.dr. F.F.S. van der Tak (RUG)

What is the effect of a dynamic training in children’s inductive reasoning skills and how is it related to children’s school performances and language development.

Promotores: F.H.J. Redig, W.T.F. den Hollander

In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.

Jan Melissen discusses the political side of the repatriation operation for Dutch citizens stranded abroad in Dutch newspaper 'de Volkskrant'.

To what extend can coercive diplomacy coerce a State to abandon its controversial nuclear program? Out of three case studies, namely Iran, Libya and South Africa, Jean Yves Ndzana’s PhD research project aims at studying the conducive conditions of coercive diplomacy.