New book on Dutch mayors governing local order and public safety.

From black holes to artificial intelligence and from drug research to data science: welcome to the fascinating world of the Faculty of Science. Our researchers, students and guests regularly give public lectures about their work. You are welcome to attend.

Drug Discovery and Safety consists of 120 European Credit Transfer System (EC) points.

Relevant safety issues are associated with hazardous materials transportation, especially when transport routes cross populated areas. This article for the Journal of Loss Prevention in the Process of Industries analyses a 2015 accident with a freight train in Tilburg, comparing it to the Viareggio…

The kidneys play a major role in the elimination of drugs. In children, the exact age-related physiological changes underlying kidney function remain largely unknown.

Science, Leiden Institute of Chemistry (LIC)

Growth hormone profiles are pulsatile and highly variable between individuals, limiting the implementation of mathemathical models to quantify an individual's secretion.

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

How do you ensure that a drug has an effect on the right protein – and nothing else? Chemist Anthe Janssen explored various methods for determining the selectivity of potential medicines. He also looked at the substance BIA 10-2474, after a man died in a French clinical trial in 2016. PhD defence on…

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)

The Drug Discovery and Safety specialisation consists of compulsory and optional components.

Supervisor: Lizi Xia

Can a new proteomics workflow be developed to link genes and gene clusters to bioactive molecules, identify novel compounds and enhance the production in the Streptomyces lividans enzyme?

Can zebrafish larvae be used as a behavioural model for screening natural products as potential neurotropic drugs?

At Leiden Bio Science Park (LBSP) Leiden University works together with the business community, the LUMC and the Municipality of Leiden.

Principles of Environmental Sciences provides a comprehensive picture of the principles, concepts and methods that are applicable to problems originating from the interaction between the living and non-living environment and mankind. Both the analysis of such problems and the way solutions to environmental…

International pharmaceuticals company Grünenthal is to open an innovation hub on the Leiden Bio Science Park. The hub will make it easier for scientists and drug developers to work together.

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua

Plant Sciences' contribution to the Bioactive Molecules research theme is to identify new plant bioactive molecules, and unravel their mechanisms of action in plant development or health, and the regulatory networks and (bio)synthetic pathways required for their production.

Developing new drugs is a difficult process. With the aid of artificial intelligence, Pharmaceutical scientist Xuhan Liu has developed methods that can help make drug design cheaper and faster. PhD defence on 15 February.

The master’s specialisation Bio-Pharmaceutical Sciences and Science Communication & Society at Leiden University is a two-year programme which combines research training in chemistry with one in techniques of communication.

By carrying out fundamental research and providing excellent education, universities become a breeding ground for innovation and entrepreneurship.

The Graduate School of Science has a centuries-old tradition in cutting edge education and research in science.

Is it possible to formulate a new conceptual foundation for attributing an evaluative role to historiography of science, without relinquishing the historiographic sensitivity of recent work in the discipline?

PhD candidates carry out a programme of independent research and additional limited) course work, culminating in production of a PhD thesis in typically 4 years.

Explore the unknown in order to be able to innovate in the distant future.

What tools can be applied to measure the output, outcome and impact of science communication efficiently and effectively?

The Faculty of Science is located at the Leiden Bio Science Park. It was founded more than two centuries ago and currently, more than 8000 people are working and studying at the eight institutes.

How can we bridge the gap between experts and the general public?

This page provides information to support your application for the Master's programme of Bio-Pharmaceutical Sciences.

What dose of medicine do you give a child? That depends to a large extent on how quickly their kidneys remove the drug from the blood. For ethical reasons it is impossible to measure this directly in little patients. PhD candidate Sinziana Cristea combined different types of modelling and lots of data…

The ability to collect and interpret huge quantities of data has become indispensable to society and academia. Leiden University is a knowledge and expertise centre for data science that places the emphasis on interdisciplinary collaboration and innovation.

The mission of the Plant Science research programme is to contribute to the sustainable production of high quality crops, flowers and high-value bio-based products. This is realised by generating fundamental knowledge of basic biological processes related to development of plants and their interaction…

In the theme Animal sciences and health research, we work with different species of animals to learn more about fundamental biological processes.

Potential drugs that seem promising in the lab, but don’t show any activity in a person: they cost the industry an incredible amount of time and money. That’s why Indira Nederpelt focuses on a more efficient search for new drugs in her PhD, by determining the kinetics of a potential drug earlier on…

Do you have questions about the Bio-Pharmaceutical Sciences master’s programme or the specialisation Drug Discovery and Safety? Please contact us.

At high doses, drug candidate BIA 10-2474 binds not only to the protein that it targets, but to other proteins as well. It thus deactivates proteins that are involved in the metabolism of nerve cells. This is what an international group of researchers from Leiden University and Erasmus MC, among others,…

Laura Heitman has been awarded a VIDI grant for her innovative drug research. Heitman strives to optimize a drug’s binding kinetics at its target in order to ultimately fight diseases effectively. She even pleads for a paradigm shift in drug discovery.

Media in the Netherlands and abroad reported extensively about the drug research led by Leiden chemist Mario van der Stelt. In this research, Van der Stelt shows which unwanted side-effects a French drug candidate has.

The master's specialisation Data Science: Computer Science at Leiden University provides students thorough knowledge and understanding of statistical and computational aspects of data analysis, including their application in databases, advances in data mining, networks, pattern recognition, and deep…

We are very happy to welcome you to spend a semester or year studying with us in the Faculty of Science. Here you will find information on your course schedules and course and exam enrolment.

In the Master’s programme in Bio-Pharmaceutical Sciences of Leiden University you are trained for a scientific career in drug research and development.

The research programme Statistical Science is concerned with the analysis and interpretation of masses of data, the quantification of uncertainty using probability models, and the development and benchmarking of algorithms and methods with these aims.

The Faculty of Science

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Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…

This NWO-funded research programme focuses on the assumptions and methodology of the writing of history of science. History of science is in many respects a flourishing discipline: it currently yields an impressive volume of studies. Systematic reflection about the ways in which history of science may…