A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.

Lecture

The need for novel drugs as well as innovations in their development and application is as urgent as ever. Below we present our vision , mission, and our key research areas.

Lecture

Lecture

Are you thinking about studying at Leiden University? Come and visit our Master’s Open Day.

Science

Many students receive their first job offer during or right after their Business Studies internship. After graduating you can also aim for a career in Bio-Pharmaceutical research.

The mission in this research group, headed by Ad IJzerman, is to design and synthesize novel and better ligands for drug targets. Drug discovery is a lengthy but inspiring adventure. It is often an interplay between academic institutes and pharmaceutical industry, in which scientists at university develop…

Grants awarded to molecular physiology research

Indira Nederpelt was elected as the winner of the Young Investigator Award for best oral presentation titled ‘’Kinetic characterization of clinically used GnRH peptide agonists’’.

Leiden University seeks to bring knowledge, academic top talents, and resources from Leiden and China together in mutually beneficial joint research projects that are content-driven, based on existing excellent research.

Are you interested in taking up an extra challenge during your master’s programme? Have you thought about applying for our Summer School programme or are you interested in developing your personal leadership style?

The Night of Discoveries is an annual event in Leiden, focusing on science and culture. The Young Academy Leiden is a recurring contributor to the Night of Discoveries.

Promotores: Prof.dr. H. S. Overkleeft, Prof.dr. G. A. van der Marel

Supervisor: Gerard van Westen

While bioinformatics methods deal with the analysis of sequence information (be it proteins or DNA), the field of cheminformatics is concerned with the analysis of small-molecule datasets.

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Leiden biotech startup Azafaros has successfully completed a funding round, raising 25 million euros of investments for developing treatments of rare metabolic disorders. The company holds exclusive license to a library of novel patented compounds discovered by experts from Leiden University.

Gerard van Westen has been appointed full Professor or Artificial Intelligence and Medicinal Chemistry. This chair has been jointly created by the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institute of Chemistry (LIC) as part of SAILS, the university stimulus program in Artificial…

Promotor: A. Kros

In vitro disease models play a fundamental role in drug research. They enable the systemic identification and validation of disease mechanisms and the discovery of possible drug targets. However, more than often, drug candidates that are identified in vitro fail in the later clinical stages of drug…

You’ve been accepted! Leiden University looks forward to welcoming you as a new student. Your next step is to prepare for your studies. Below you can find some tips to help you get a head start as you embark on your studies at Leiden University.

Leiden University offers you several services related to career orientation and job application skills.

Source: J Cheminform, Volume 6, Issue 1 (2014)

The current projects of the Molecular Physiology group focus on kinases and proteins of the endocannabinoid system.

This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).

The System Biomedicine and Pharmacology specialisation consists of compulsory and optional components.

With an MSc degree in BPS and Science Communication & Society you are well prepared for a broad array of career prospects in research or industry. The master’s degree is an excellent preparation for a career at the interface of science and public affairs.

Research question

Promotor: Prof.dr. B. van de Water, Co-promotor: L.S. Price

Supervisor: Xue Yang

The two-years MSc programme spans the entire spectrum of Analytical BioSciences, Biopharmaceutics, Drug Delivery Technology, Medicinal Chemistry, Pharmacology and Toxicology.

To be eligible for Drug Discovery and Safety at Leiden University, you must meet the following admission requirements.

A full overview of MacBio PhD Theses.

Media in the Netherlands and abroad reported extensively about the drug research led by Leiden chemist Mario van der Stelt. In this research, Van der Stelt shows which unwanted side-effects a French drug candidate has.

Supervisors: Willem Jespers (Uppsala University), Gerard van Westen (LACDR), David Gloriam (Copenhagen University)

An integrated approach for the simultaneous prediction of polypharmacology and binding affinity/potency of small molecules.

From the Big Bang to superconductivity. Many ground-breaking discoveries have been made in Leiden University’s long history.

Erik Danen is looking at how to inhibit tumours that do not respond well to medicine – and he is making some headway. The Professor of Cancer Drug Target Discovery studies the interaction between tumour cells and their surroundings. Inaugural lecture on Friday 10 May.

The IBL represents the core of modern biological research at Leiden and we interact closely with the other life science Partner Institutes in the faculty:

Prof.Dr. Herman van Vlijmen was appointed as Professor of Computational Drug Discovery at the Division of Medicinal Chemistry in Leiden on April 15th, 2008. He will give his Inaugural Lecture on May 18th, 2009.

Supervisor: Maarten Doornbos

On May 3rd, we had a successful LACDR Spring symposium. Traditionally the Spring symposium is an important platform for our PhD’s. We have highlighting the research activities of our PhD candidates. As Keynote speaker, Prof. dr. Matthias Mayer of the University of Heidelberg has given an interesting…

Leiden chemists have proposed a new model for enzymatic reactions, in which the flexibility of the substrate is much more important than previously thought. Their results are paradigm-shifting and could have major implications for drug research and enzyme engineering. Publication in Angewandte Chemi…

Which immune mechanisms are involved in host defense against Staphylococcal infection?

Eight interdisciplinary programmes were launched at Leiden University in 2020. They focus on intensifying interdisciplinary collaboration throughout the University, and respond to issues affecting the world today and agendas such as the UN Sustainable Development Goals.

Leiden chemists have developed a new technique with which they can determine the role of kinases – a group of proteins – in a living cell. This technique makes it easier to find new drug targets for diseases such as cancer and rheumatoid arthritis. The team published the findings in the journal Nature…