Target selectivity is an important aspect of any drug molecule, and certainly a parameter to be optimized. That is not trivial for a number of reasons. First of all hundreds of drug targets (receptors, enzymes, ion channels) exist, and no single lab in the world has assays for all of them.

As LUC The Hague only has 200 places available for first year students, we select students based on multiple factors in order to assess best fit.

The Bachelor programme Psychology will admit a limited number of students (Numerus Fixus). A selection process will determine which applicants best fit our programme. Also, it is a good way for you to discover if Psychology in Leiden is the programme for you.

Exchange selecting courses and projects

Our selection and placement procedure starts with your application (i.e. prior to 15 January of the calendar year in which you intend to start) and ends with—hopefully—an invitation to you to enrol as an IRO student. This page tells you all you need to know about the steps to be taken in between.

Did we spark your interest in the Leadership Programme (LLP) and are you looking forward to take on this challenge in the coming academic year? Apply now! The LLP starts once every year, on the 7th of November, and ends in June.

Directions to the Pieter de la Court Building, which houses the Faculty of Social and Behavioural Sciences, PLATO and the African Studies Centre Leiden. Plus, information about parking facilities close by.

The Bachelor Honours Programme Sustainability is open for enrollment to motivated second- and third-year bachelor's students of Leiden University, TU Delft and Erasumus University. Additional requirements can be found below.

The Young Academy Leiden is looking for new members. In this round, candidates are nominated by the Faculty Boards and the Executive Board of LUMC.

Promotores: R. Tijdeman, K.J. Batenburg

Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

EU Cyber Direct – EU Cyber Diplomacy Initiative supports the European Union’s cyber diplomacy and international digital engagements in order to strengthen rules-based order in cyberspace and build cyber resilient societies. To that aim, we conduct research, support capacity building in partner countries,…

Promotor: Prof.dr. M.K. Richardson, Co-Promotor: F. Witte

This thesis describes the importance of being able to control the selectivity of potential drug candidates.

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

Examining if large scale application of new energy pathways can be constrained by materials and emissions.

Language learners in higher education increasingly conduct out-of-class self-directed learning facilitated by mobile technology. This project aims to explore how university students use mobile technology for their self-directed language learning and investigate factors that influence their self-directed…

If you do not have immediate plans to continue with a master’s programme after your bachelor there are all kinds of possibilities to fill your time with. Think of, for example, travelling possibly in combination with learning a language, working, volunteer work, an administrative year, etc.

Sustainable energy from wind and solar is most readily available near the sea.

This dissertation looks into the role of discretion granted by EU directives (Article 288 Treaty on Functioning of the European Union) in legislative decision-making and national transposition processes of these directives.

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.

How can the legal and socio-legal research skills of Indonesian jurists be increased in order to promote legal certainty and to strengthen the capacity of the judicial training in the country?

On 10 February 2022, Christian Mommers defended the thesis 'Voluntary return and the limits of individual responsibility in the EU Returns Directive'. The doctoral research was supervised by Prof. P.R. Rodrigues and Prof. P. Boeles.

The Dutch atlas with pesticides concentrations in surface waters have been overhauled. This new, free accessible, website is in line with the European Framework Directive on Water (In Dutch: KRW).

Kohei Suzuki, Assistant Professor at Institute of Public Administration, and two other authors researched the topic of innovation by governments in response to expected population decline.

Both Europe and Latin America face challenges globally and at home. Conflicts over land and resources have been resurgent in recent years.

This dissertation focuses on the overt marking of φ features encoded on perfective active auxiliaries in a group of Southern Italian dialects.

One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…

Lecture

The path to rational drug and dose selection

Governance and Global Affairs, Institute of Security and Global Affairs

This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.

A Selection of the Poems of Sir Constantijn Huygens (1596-1687) was published in July 2015, edited and translated by Adriaan van der Weel and Peter Davidson.

A thorough description of the relationships among languages and their social environment in a given context, reflecting an ecological perspective, involves attention to the agency of local actors, and the policies, discourse, and ideologies that surround them.

It is often said that the links between political parties in Africa and their voters are clientelist, rather than programmatic. The familiar image is that of African ‘big men’, displaying personal wealth while being respected and celebrated in the community for sharing their riches. Yet, political scientist…

How do parliamentarians secure their political future? Are their activities in the legislature connected to their place on the candidate list from one election to the next? Political scientists Tom Louwerse and Cynthia van Vonno examine the Dutch case. Their main finding is that speaking in the plenary…

CML report 192

Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent

Juurlink

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

Source: Org Biomol Chem, Volume 13, Issue 8, pp. 2407-22 (2015)

Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.

FGGA students Amber Klompmaker (Master in Public Administration) and Imogen Liu (Research Master in Political Science and Public Administration) have been selected to participate in the Political Economy of Capitalism workshop of the Young Scholars Initiative of the Institute of New Economic Thinking…

EUniWell –the European University for Well-Being in which Leiden University and six other universities collaborate – is among the consortia selected for funding in the ‘European Universities Initiative’. The alliance will receive funding of 5 million euros from the European Commission.

How do you ensure that a drug has an effect on the right protein – and nothing else? Chemist Anthe Janssen explored various methods for determining the selectivity of potential medicines. He also looked at the substance BIA 10-2474, after a man died in a French clinical trial in 2016. PhD defence on…