713 search results for “direct-infusion mass spectrometry” in the Public website
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Eelco van der Maat
Faculty of Humanities
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The interplay between stars, gas and dust in faint star-forming galaxies
When observing star-forming galaxies, we are not only seeing stellar light, but we also see how this interacts with galactic gas and dust. This thesis contains studies of the stellar, nebular and dust properties of low mass star-forming galaxies.
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Postdoc Unlocking Nature’s Pharmacy from Bogland Species
Science, Institute of Biology Leiden (IBL)
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Climate Change and Natural Isotopes
This project, under the supervision of Prof. Dr. Hans van der Plicht, comprises several studies aimed at the use of isotopes occurring naturally in organic material as tracers for both the climate change and its cultural impact at about 6200 BC. The research will be carried out by the co-applicant at…
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Neandertal Legacy
The genetic material of currently living Europeans is partly of Neandertal origin. Were our ancestors successful because they were hybridising and interacting with the local populations they encountered when migrating into new places? Reconstructing our evolutionary trajectory is key for rethinking…
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The excavation of the Paardenmarkt Alkmaar
In June-August 2010 large scale excavations were executed on the cemetery belonging to the monastery, an area now termed the Paardenmarkt, by Hollandia Archeologen in cooperation with Leiden University. During the course of nine weeks, the students from the former minor Human Osteoarchaeology excavated…
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Young suns and infant planets: Probing the origins of solar systems
Even though more than 4000 extra-solar planets are known today, only a small fraction of these has been captured in an image. To better understand the planet formation mechanisms in solar-like environments we started the Young Suns Exoplanet Survey (YSES).
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Modeling interstellar bubbles: near and far
Promotor: Prof. dr. A.G.G.M. Tielens
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Shadow Libraries: The Politics of Mass Digitization
Lecture
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Small scale kinematics of massive star-forming cores
Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: M.R. Hogerheijde
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Sterile neutrinos in the early Universe
Promotor: A. Achúcarro, Co-promotor: A. Boyarsky
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Political Religion Beyond Totalitarianism
The eleven innovative essays in this volume explore the notion that all forms of modern mass politics, including liberal democracies, need such a form of sacralization of politics to function.
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The origins of friction and the growth of graphene, investigated at the atomic scale
Promotor: J.W.M. Frenken
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Studying dark matter using weak gravitational lensing : from galaxies to the cosmic web
Of all the mass in our Universe, 80% is thought to consist of a hypothetical and invisible substance called dark matter (DM).
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Diagnosis and treatment of obese children with insulin resistance
Promotors: C.A.J. Knibbe, Anthonius de Boer, Co-promotor: M.M.J. van der Vorst
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The Construction of Nationalism in Chinese Media Events in the Reform Era
On 12 May 2022 Qiaoqi Zhang successfully defended a doctoral thesis and graduated.
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Micro-Blogging and Media Policy in China
Yuxi Nie defended her thesis on 15 October 2019.
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Pressure groups
Where did the new generation of antislavery activists get their inspiration to organize in large-scale pressure groups?
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High-throughput mass spectrometric N-glycomics
PhD Defence
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Novel mass spectrometric applications in clinical microbiology
PhD Defence
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Ongoing excavations at Les Cottés (near Poitiers, France)
Les Cottés is one the rare site in western Europe with occupations in sequence by the very last Neandertals and the first anatomically modern humans.
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Collaborative and effective drug development
There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…
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Lipid to protein ratio plays an important role in the skin barrier function of atopic eczema patients
OBJECTIVES: To determine whether the lipid/protein ratio and the total dry SC mass per surface area are related with the skin barrier function of controls and AE patients.
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Identifying the origins of galaxy formation
This thesis investigates how galaxies form and what diversifies the evolutionary histories of galaxies.
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Simulating the birth environment of circumstellar discs
Circumstellar discs are the reservoirs of gas and dust that surround young stars and have the potential to become planetary systems.
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The puzzle of protoplanetary disk masses
PhD Defence
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Language guardians: The role of mass media in linguistic prescriptivism
Lecture
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Weighing the Dark: Cosmological Applications of Gravitational Lensing
Promotor: K. Kuijken, Co-Promotor: H. Hoekstra
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Structural Health Monitoring Meets Data Mining
Promotor: Prof.dr. J.N. Kok, Co-promotor: Dr. A.J. Knobbe
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Protostellar jets and planet-forming disks: Witnessing the formation of Solar System analogues with interferometry
The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.
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Behavioral implications of Neandertal energetics
Recent studies of Neandertal body mass and skin surface indicate raised energetic requirements in this lineage compared to anatomically modern humans.
- Nuclear Diplomacy
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Retributive or reparative justice? Explaining post-conflict preferences in Kenya
This study adds nuance to the empirical literature that interrogates the link between exposure to mass violence and post-conflict justice preferences.
- Networked Diplomacy
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StepTalk: Mass Starvation: The History and Future of Famine
Debate, StepTalks
- Lecture: 'Pervasive Punishment: Making sense of 'mass supervision’
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Flow Cytometry Core Facility
The LUMC Flow Cytometry Core Facility accommodates all research and diagnostic flow cytometry equipment of the LUMC.
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Unveiling dark structures with accurate weak lensing
Improvements of weak gravitational lensing shape measurements are presented and some used for data analysis.
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Metabolomics Facility
The Metabolomics Facility of the University of Leiden has brought together two research groups from the Faculty of Science that are well-known for their expertise in two different fields: the Biomedical Metabolomics Facility Leiden, experts in clinical metabolomics and the Natural Products Laboratory,…
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Research
The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.
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Unfolding secrets of catalysts
To construct catalysts that can produce fuels from CO2 innumerable times, we need to learn much more about how catalysis works. Irene Groot is conducting groundbreaking research into catalysis at the atomic level.
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Hit and Lead Optimization
The goal of hit and lead optimization is to optimize suitable chemical starting points that can modulate a drug target. The methods and technologies used are similar to those in Hit Discovery, but once the compound has shown activity in an animal model, it moves from 'hit' to 'lead.'
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Postdoc, (Metabolomics LED-light-grown plants)
Science, Institute of Biology Leiden (IBL)
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Operando research in heterogeneous catalysis
The nanoscale structure of a catalyst under reaction conditions determines its activity, selectivity, and stability. For the production of sustainable energy and materials, new catalysts are needed. By understanding the structure-activity relationships of catalysts under reaction conditions, insight…
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Teaching
Research projects for students of the University of Leiden and other Dutch Universities are often available at the MacBio group. The research lines are also described in the Research section. For details of specific projects contact the supervisor (Ubbink, Dame, Boyle).
- El-Hosh
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Postdoc candidate in biochemistry / cell glycobiology / protein targeted degradation
Science, Leiden Institute of Chemistry (LIC)
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Postdoc, (Unlocking Nature’s Pharmacy from Bogland Species)
Science, Institute of Biology Leiden (IBL)
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Innovation in treatment and care
Treatment and care for cancer patients is becoming increasingly advanced. For example, surgeons can now perform operations with much greater precision, and therapeutic vaccines are being developed to prompt the patient’s immune system to fight cancer. Work is also being done on better early diagnostics,…
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2 PhD candidates to study the molecular mechanisms of the Hsp70 chaperone in neurodegenerative disease
Science, Leiden Institute of Chemistry (LIC)