Dissertation

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Social anxiety runs in families, but the neurobiology underlying this genetic vulnerability is until now largely unknown. The unique Leiden Family Lab study on Social Anxiety Disorder (LFLSAD) aims to broaden our knowledge with respect to this genetic susceptibility.

Developmental and Educational psychology is concerned with the developmental course and dynamics of cognition, self-regulation, and emotional competence, and the implications for educational and clinical practice.

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The Developmental Psychology specialisation of the Research Master’s in Psychology offers a strong theoretical background to provide the varied knowledge-base needed for a thorough understanding of emotional and cognitive development across childhood and adolescence.

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Although exposure therapy is the gold-standard treatment of posttraumatic stress-disorder (PTSD), only half of the patients adequately benefit from it. Based on recent insights into the mechanisms of extinction, this project examines strategies and techniques to improve exposure treatment outcome in…

Children with autism spectrum disorder experience serious challenges in social functioning, which threatens their development in many areas of functioning.

How to come to valid risk stratification of alcohol use disorder?

1. Social anxiety and factors determining school success in children. 2. Brain development in relation to cognitive, social and emotional development in adolescence

One of the current research projects funded by the profile area Political Legitimacy is the research group From Disorder to Order: Conflict and the Resources of Legitimacy.

Which adolescents are more at risk of developing social anxiety disorder later in life?

This thesis is devoted to an in-depth examination of the various effects of disorder in the cuprate high-temperature superconductors.

The key question addressed in this family study is whether the psychophysiological and neurocognitive abnormalities often reported in SAD patients are heritable and can thus be found in family members of SAD patients as well. Determination of heritability of these deficiencies is essential for endophenotyping.…

Can chemical safety assessment be improved with zebrafish embryo-based reporter assays?

The aim of the research master’s programme Developmental Psychopathology in Education and Child Studies is to promote the scientific development of young academics on the path to becoming independent researchers within education and child studies and related disciplines.

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.

Promotor: Prof.dr. G.P. van Wezel

How does stress affect different components of behavioral impulsivity and aggression in patients with Borderline Personality Disorder compared to clinical controls (patients with Attention Deficit Hyperactivity Disorder) and healthy controls?

1. What is the exact role of PIN proteins in PAT? 2. How is PIN polarity established, and how is it modulated by AGC kinase-mediated phosphorylation? 3. What is the role of the AGC kinase, as modulators of PAT, in translating environmental signals, such as gravity, light or mechanical stress, to plant…

What are the developmental pathways to social anxiety (disorder), the causal processes and maintaining factors? How do these factors interact in the development of social anxiety disorder? How can this knowledge be used to design and implement effective preventive intervention programs for youth?

This longitudinal study is focused on neurodevelopmental problems in young children with XXY, XXX and XYY, aged 1 to 6 years.

New policies, institutional configurations, and state-market relations are emerging outside of East Asia, as new developmental states move beyond the historical experience of East Asian development. Yet, the ‘developmental state’ is still relevant. This book, edited by Jewellord Nem Singh (Institute…

Read about the impact of past research

An assessment approach that tailors to children’s instructional needs

Neurobiological, cognitive and behavioural measurements of normal and abnormal child development.

In a recent study, Dr. Moji Aghajani and colleagues show that adolescents with a severe form of Conduct Disorder (CD) -with limited prosocial emotions- require an unusually large amount of brain capacity to read emotional faces. These effects were found in comparison to CD youth without limited prosocial…

Why do children with an Autism Spectrum Disorder (ASD) have difficulties with acquiring emotion regulation skills; and how is this related to their social impairments and comorbid psychopathology?

This thesis describes the functional analysis of the Arabidopsis AHL15 gene.

How do dissociative states affect the ability to suppress emotional distraction (in the context of a working memory task) in patients with Borderline Personality Disorder?

Does an Emotional Working Memory Training show a beneficial transfer effect on emotion regulation (reappraisal) capacities in patients with Borderline Personality Disorder?

Trust and reciprocity are two important social behaviors that help adolescents to navigate their social world successfully. In their empirical article in Journal of Research on Adolescence, van de Groep, Meuwese, Zanolie, Güroğlu, and Crone describe the development of trust and reciprocity in adolescents…

What is the role of emotion regulation in coping with interpersonal feedback?

Which criteria do ED patients and therapists evaluate as most relevant for recovery? Do patients and therapists differ in their evaluations? Do eating disorder patients differ from a healthy control group in their scores on the Recovery Scale?