Dissertation

-

Social anxiety runs in families, but the neurobiology underlying this genetic vulnerability is until now largely unknown. The unique Leiden Family Lab study on Social Anxiety Disorder (LFLSAD) aims to broaden our knowledge with respect to this genetic susceptibility.

Developmental and Educational psychology is concerned with the developmental course and dynamics of cognition, self-regulation, and emotional competence, and the implications for educational and clinical practice.

-

The Developmental Psychology specialisation of the Research Master’s in Psychology offers a strong theoretical background to provide the varied knowledge-base needed for a thorough understanding of emotional and cognitive development across childhood and adolescence.

-

Although exposure therapy is the gold-standard treatment of posttraumatic stress-disorder (PTSD), only half of the patients adequately benefit from it. Based on recent insights into the mechanisms of extinction, this project examines strategies and techniques to improve exposure treatment outcome in…

What is the relation between brain development and social and cognitive development across childhood, adolescence and adulthood?

The precise psychobiological mechanisms leading to chronic physiological stress responses have not been sufficiently explained, although stress is a major risk factor for disease and early death. A problem for conventional stress theory is that most of these responses seem to occur in situations without…

Social and Behavioural Sciences, Psychology

Children with autism spectrum disorder experience serious challenges in social functioning, which threatens their development in many areas of functioning.

How to come to valid risk stratification of alcohol use disorder?

We developed the bitterling as a unique, well-studied model organism in the area of the evolutionary ecology of brood parasitism. The bitterling-mussel relationship, interspecific mussel host preference, and mussel gill structure are studied in detail, to help understand the developmental adaptation…

Social anxiety and factors determining school success in children. Brain development in relation to cognitive, social and emotional development in adolescence.

Which adolescents are more at risk of developing social anxiety disorder later in life?

One of the current research projects funded by the profile area Political Legitimacy is the research group From Disorder to Order: Conflict and the Resources of Legitimacy.

In this thesis we use Josephson and noise scanning tunneling microscopy for the study of conventional, unconventional (iron-based) and disordered superconductors. On the one hand, Josephson scanning tunneling microscopy allows us to directly visualize the superfluid density with high spatial resolut…

This thesis is devoted to an in-depth examination of the various effects of disorder in the cuprate high-temperature superconductors.

The key question addressed in this family study is whether the psychophysiological and neurocognitive abnormalities often reported in SAD patients are heritable and can thus be found in family members of SAD patients as well. Determination of heritability of these deficiencies is essential for endophenotyping.…

Can chemical safety assessment be improved with zebrafish embryo-based reporter assays?

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

PhD defence

How does stress affect different components of behavioral impulsivity and aggression in patients with Borderline Personality Disorder compared to clinical controls (patients with Attention Deficit Hyperactivity Disorder) and healthy controls?

Promotor: Prof.dr. G.P. van Wezel

1. What is the exact role of PIN proteins in PAT? 2. How is PIN polarity established, and how is it modulated by AGC kinase-mediated phosphorylation? 3. What is the role of the AGC kinase, as modulators of PAT, in translating environmental signals, such as gravity, light or mechanical stress, to plant…

The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.

What are the developmental pathways to social anxiety (disorder), the causal processes and maintaining factors? How do these factors interact in the development of social anxiety disorder? How can this knowledge be used to design and implement effective preventive intervention programs for youth?

This longitudinal study is focused on neurodevelopmental problems in young children with XXY, XXX and XYY, aged 1 to 6 years.

New policies, institutional configurations, and state-market relations are emerging outside of East Asia, as new developmental states move beyond the historical experience of East Asian development. Yet, the ‘developmental state’ is still relevant. This book, edited by Jewellord Nem Singh (Institute…

An assessment approach that tailors to children’s instructional needs

Why do children with an Autism Spectrum Disorder (ASD) have difficulties with acquiring emotion regulation skills; and how is this related to their social impairments and comorbid psychopathology?

How do dissociative states affect the ability to suppress emotional distraction (in the context of a working memory task) in patients with Borderline Personality Disorder?

Does an Emotional Working Memory Training show a beneficial transfer effect on emotion regulation (reappraisal) capacities in patients with Borderline Personality Disorder?

This thesis describes the functional analysis of the Arabidopsis AHL15 gene.