174 search results for “cytotoxic t lymphocytes ctls ” in the Public website
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Modelling the role of cytotoxic T lymphocytes in tumour regression
Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.
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defined adjuvanted vaccine for induction of antigen-specific T cell cytotoxicity
For effective cancer immunotherapy by vaccination, co-delivery of tumour antigens and adjuvants to dendritic cells and subsequent activation of antigen-specific cytotoxic T cells (CTLs) is crucial. In this study, a synthetic long peptide (SLP) harbouring the model CTL epitope SIINFEKL was encapsulated…
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Influenza T-cell epitope-loaded virosomes adjuvanted with CpG as a potential influenza vaccine
Influenza CD8(+) T-cell epitopes are conserved amongst influenza strains and can be recognized by influenza-specific cytotoxic T-cells (CTLs), which can rapidly clear infected cells. An influenza peptide vaccine that elicits these CTLs would therefore be an alternative to current influenza vaccines,…
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Bioorthogonal deprotection strategy to study T-cell activation and cross- presentation
Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.
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Modelling the role of cytotoxic T lymphocytes in tumour regression
PhD Defence
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Wim 't Gilde
ICT Shared Service Centre
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Petra 't Hart
Faculty of Humanities
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Jeroen 't Hart
Expertisecentrum SOZ
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Leendert 't Hart
Faculteit Geneeskunde
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Joest 't Hart
Faculteit Rechtsgeleerdheid
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Miranda van 't Wout
Faculty of Humanities
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Marjorie in 't Veld
Universitaire Bibliotheken Leiden
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Mark van 't Wout
ICT Shared Service Centre
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Eva van 't Loo
Universitaire Bibliotheken Leiden
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Marco van 't Hart
Universitair Facilitair Bedrijf
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Carlijn van t Hoff
Faculteit der Sociale Wetenschappen
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Mark van 't Veer
Universitair Facilitair Bedrijf
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Arie in 't Veld
Faculteit der Sociale Wetenschappen
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Kayle van 't Klooster
Faculty Governance and Global Affairs
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Arno van 't Hoog
Faculty of Humanities
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Adriaan in 't Groen
Faculty Governance and Global Affairs
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Thirza van 't Rood
Faculteit der Sociale Wetenschappen
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Aurelie van 't Slot
Faculty of Humanities
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Erik van 't Klooster
Faculteit Rechtsgeleerdheid
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Texel in 't Veen
Faculty of Humanities
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Bas van 't Hof
Science
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Esmaralda van 't Net
Faculteit der Sociale Wetenschappen
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Rob in 't Veld
Faculty Governance and Global Affairs
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Anna van 't Veer
Faculteit der Sociale Wetenschappen
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Coen van 't Veer
Faculty of Humanities
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Maarten van 't Zelfde
Science
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T.P. Shoshkov
Science
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T.E. Jaroszek
Faculty of Humanities
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Overview
The aim of the division of Systems Biomedicine and Pharmacology lies in the development of personalised medicine strategies, and development of new systems-based approaches in translational and clinical pharmacology.
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Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis
Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.
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Elina van 't Zand-Kurtovic
Faculteit Rechtsgeleerdheid
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When Art Isn’t Real
How an initially valueless object becomes worth hundreds of millions. And vice versa.
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From Stem Cells to Functional Lymphocytes
PhD Defence
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Formulation of influenza T cell peptides: In search of a universal influenza vaccine
Promotoren: G.F.A. Kersten, W. Jiskoot, Co-promotor: J-P. Amorij
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Valedictory Lecture prof.mr. T.J. Mellema-Kranenburg
Valedictory Lecture
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Doesn't Play Well With Others
What are the socio-political implications of performing Johannes Brahms's chamber music in 19th-century style?
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Evaluation of donor lymphocyte infusions after allogeneic stem cell transplantation
PhD Defence
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Why don't drugs make it to the market?
How can we extend the drug residence time to combat diseases more effectively?
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Gold nanoparticle-peptide conjugates for biomedical applications
Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.
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Don't Blink: Detecting transiting exoplanets with MASCARA
This thesis describes the Multi-site All-Sky CAmeRA (MASCARA), which consists of two small robotic telescope designed to detect exoplanets around the brightest stars in the sky.
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Lipid bilayers decorated with photosensitive ruthenium complexes
Promotor: E. Bouwman, Co-promotor: S. Bonnet
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Een gedreven buitenstaander: J.H. van 't Hoff de eerste Nobelprijswinnaar voor Scheikunde
This dissertation presents a new perspective on the life, work and character of the Dutch physical chemist Jacobus Henricus van ’t Hoff, first recipient of the Nobel Prize in Chemistry, and one of the most important and colourful scientists in Dutch history. The image of Van ’t Hoff that emerges from…
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Canonical and non-canonical Wnt signaling in hematopoiesis and lymphocyte development
PhD Defence
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Jewellord T. Nem Singh & Jesse Salah Ovadia (Eds.), Developmental States beyond East Asia
New policies, institutional configurations, and state-market relations are emerging outside of East Asia, as new developmental states move beyond the historical experience of East Asian development. Yet, the ‘developmental state’ is still relevant. This book, edited by Jewellord Nem Singh (Institute…
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Mast cells as immune regulators in atherosclerosis
Cardiovascular syndromes are the major cause of death in Western societies.