7 search results for “crispr-cas9” in the Public website
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Live or let die: the intracellular fate of pathogenic mycobacteria
How do mycobacteria subvert the defenses of host immune cells?
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Precision modeling of breast cancer in the CRISPR era
The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.
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Packaging and accessing DNA molecules
Our DNA molecules are packaged by proteins in compact structures. The aim of this project is to understand how modern gene editing techniques nevertheless get access to their target in the DNA.
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Plant ageing, rejuvenation and life history strategy
What are key regulators of plant ageing that can reverse ageing in plants (rejuvenation), and how can we use this knowledge to improve crop plants?
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2 PhD candidates in Bioinformatics Stem Cells-Based Therapies Development
Science, Leiden Academic Centre for Drug Research (LACDR)
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‘Unimportant’ plant gene turns out to be essential
Leiden biologists have shown that a gene present in plants, animals and yeasts does play an important role in plants, although for years the gene was considered unimportant. It turns out the gene plays a crucial role in the development of vascular tissue in plants. Publication in Nature Plants on 11…
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Chemical approaches to control the in vivo behavior of nanomedicines
Lecture, Van Leeuwenhoek Lecture on BioScience