Students, staff members and alumni of the MA International Relations programme gathered together on the first student-alumni career networking event to spend a sunny Friday reflecting on the programme and its career opportunities.

On Thursday 15 February, the second ILS Lunch Seminar of 2018 took place. Prof. Jean-Pierre van der Rest and Maria Berghuis gave two excellent presentations on their particular research topics.

PhD defence

PhD defence

Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?

Macrophages and atherosclerotic lesions The infiltration of monocytes in the arterial wall, their differentiation to macrophages, and the subsequent accumulation of cholesterol in these macrophages initiate the process of atherosclerosis. We study the importance of specific genes in macrophages for…

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…

Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar-Jagalska

Discovery of metastasis promoting candidate drug targets

We investigate reaction systems, a novel computational model gleaned from the biochemical reactions taking place in living cells and information processing in nature.

The Netherlands Organisation for Scientific Research (NWO) has awarded Veni funding to seventeen researchers who recently obtained their PhD. This award offers promising young scientists the opportunity to develop their own ideas over a period of three years.

Research aims: Identification of key genes involved in programming the cellular architecture of A. niger & Genetic engineering of A. niger in order to improve its secretory capacities and rheological behavior under industrial fermentation conditions.

Promotor: P.M. Brakefield

Lecture

Thomas Bakkum en Tom van der Wel, two PhD candidates from the Leiden Institute of Chemistry, have both won poster prizes at the EMBL Chemical Biology Conference 2018 in Heidelberg.

A novel in vivo model system for studies on glucocorticoid resistance

Lecture

Promotor: M. Ubbink, Co-Promotor: R. T. Dame

The group Theoretical Physics of Life Processes, led by Helmut Schiessel, focuses on the physics of chromatin, the DNA-protein complex that fills the nuclei of eukaryotic cells.

Chromatin is an ubiquitous protein-DNA complex that forms the structural basis of DNA condensation in all eukaryotic organisms.

Cellular stress response pathways are activated upon exposure to chemicals and help organisms deal with various molecular dangers (e.g. oxidative stress). When these pathways become hyper-activated an adverse response takes place and cells die, which may lead to organism-level toxicity such as drug-induced…

We study cell-fate decision-making using embryonic stem cells as a model system. Stem cells integrate a large number of cues to direct their development into a great variety of cell types.

The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine.

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

The key question addressed in this family study is whether the psychophysiological and neurocognitive abnormalities often reported in SAD patients are heritable and can thus be found in family members of SAD patients as well. Determination of heritability of these deficiencies is essential for endophenotyping.…

Through his project we will unravel the global regulatory networks that control gene expression in Streptomyces bacteria and allow them to properly respond to major changes in the environment; we will then harness this knowledge to activate and identify novel antibiotics

How is vegetative development regulated in plants and how does this affect a plant’s life history strategy?

We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.

In the research programme Microbial Sciences we perform state-of-the-art research in the field of biotechnology and microbial sciences.

We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.

About nine million people worldwide contract tuberculosis each year. Research into new treatment for this disease has received fresh stimulus with more efficient techniques and a new understanding of how the tuberculosis bacteria works.

In August 2018, the fourth edition of the teaching and learning materials

PhD defence

Louis Verreth and Jeroen De Keyser recently published a critical edition of Francesco Filelfo’s Latin translation of the Rhetorica ad Alexandrum (Edizioni dell'Orso).

'In Perspective' is the quarterly publication of the Faculty of Humanities in which we bundle some of our most high-profile stories. In Perspective is printed in limited quantities (currently only available in Dutch), spread amongst relations and partners and offered on coffeetables within our buildings.…

This summer school is for graduate (MA and PhD) students and researchers who have an interest in handwritten materials, editing, and the tradition of editing in the Muslim world. It offers theoretical lectures as well as hands-on practice with samples from the world-famous collections of the Leiden…

In Universal Śaivism Peter Bisschop provides a critical edition and annotated translation of the sixth chapter of the Śivadharmaśāstra `Treatise on the Religion of Śiva’, the so-called Śāntyadhyāya 'Chapter on Appeasement’. The Sanskrit text is preceded by an extensive introduction on its composition,…

PhD defence

PhD defence

How can we prevent drug-induced liver and kidney damage? PhD candidates Marije Niemeijer and Lukas Wijaya investigated what happens in the cells during the onset of this damage: a stress response. Both focused on a different subtopic and made some interesting discoveries.

Lecture

PhD defence

PhD defence

PhD defence