Promotor: E. Bouwman, Co-Promotor: S. Bonnet

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

Promotor: M.A.G.J. Orrit

Science, Leiden Academic Centre for Drug Research (LACDR)

Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease progression and treatment response. A Systems Medicine approach, based on computational…

Promotores: H. Schiessel, G.T. Barkema

PhD Defence

The aim of this thesis is to develop and study a robust and adaptable scaffold for supramolecular polymer self-assembly in water.

The study adviser (or coordinator) is an expert on all aspects of the Media Technology MSc program. If you have any questions or concerns about your studies, whether they be of a practical or academic nature, you can contact your study adviser.

The study adviser (or coordinator) is an expert on all aspects of the Media Technology MSc program. If you have any questions or concerns about your studies, whether they be of a practical or academic nature, you can contact your study adviser.

In my research, I focus on cooperation, social dilemmas, tacit coordination, uncertainty, sanctions and trust.

This month, a paper was published in Nanoscale by scientists from Dr. Alireza Mashaghi group at the Systems Biomedicine and Pharmacology Division in collaboration with the group of Dr. Sander Tans from TU Delft/AMOLF. In this paper, the authors studied how nanoscale spatial confinement affects the fold…

This dissertation provides a systematic description of English and Afrikaans verbal pseudo-coordination and a formal analysis couched in the Minimalist program.

Governments are increasingly facilitating the roll-out of so-called “smart meters”, a technology for measuring energy consumption that are able to transmit and receive data using a form of electronic communication. However, implementation has been slow or even stalled.

Co-ordination Action for Innovation in Life-Cycle Analysis for Sustainability: deepening, broadening and leaping forward the LCA methodology.

There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…

Molecules are extremely hard to see in visible light, especially without using fluorescence. Leiden physicists have now made their optical technique sensitive enough to image the molecules of their interest in all sizes. Publication in Nanoletters.

A full overview of MCBIM PhD theses.

Are you passionate about sustainability? Do you see opportunities to make Leiden University more sustainable? Are you able to inspire, engage and empower both students and staff? This is your chance to contribute!

Are you passionate about sustainability? Do you see opportunities to make Leiden University more sustainable? Are you able to inspire, engage and empower both students and staff? This is your chance to contribute!

Source: Bioorg Med Chem, Volume 23, Issue 14, pp. 4034-49 (2015)

The group of Dr. Roxanne Kieltyka designs and synthesizes molecules that self-assemble into polymeric materials using specific non-covalent interactions. These substrates can be used for numerous applications in medicine ranging from disease detection to cell delivery depending on the (bio)molecular…

The research described in this thesis focused on the preparation of S/N functionalized carbene ligands and their transition metal complexes, and the exploration of their application as electrocatalysts for proton reduction.

This thesis describes the design, characterization and application of dextran based crosslinked network.

The focus of our theoretical research is understanding the behaviour of soft condensed matter, physical matter which is deformed or structurally altered by thermal fluctuations or small stresses.

Within this project, PeptoMiktoStars were realized through an orthogonal protecting group strategy and should be investigated further regarding their potential as drug delivery systems in the field of drug delivery to inflamed areas in cancer, bacterial infections or autoimmune diseases.

While colloidal aggregates are often undesirable due to their random shapes, we exploit them as a starting point to synthesize patchy particles.

PhD Defence

The Delivery of Biotherapeutics research group is led by Prof. Matthias Barz and focusses on the synthesis and characterization of polypept(o)ids and their application in nanomedicine to improve existing therapies or enable novel diagnostic or therapeutic approaches.

A common assumption in chemistry is that the coordination number of a catalyst's surface determines the reactivity of the reaction it catalyses. Strikingly, Leiden chemists have now proven that this is not true for nature’s most simple chemical reaction: the dissociation of hydrogen. The researchers…

For many new international students, moving to the Netherlands and getting used to Dutch culture and customs can be quite challenging. Luckily the Humanities Buddy Programme is here to help! The new coordinator of the programme, Bob van der Horst, will introduce himself and explain more about the buddy…

Vitelli

When does it rain when air is oversaturated with moisture? How does an infection spread among the population? The problems that mathematician Professor Frank den Hollander tries to solve come from physics, chemistry and biology.

We have recently discovered that there are biological proteins that phase separate out of solution much the way oil will de-mix from water (see movie). These form dense, liquid-like phases called protein condensates.

The new project INFLANET will train young scientists in Europe to become experts in inflammation research. Professor Annemarie Meijer from the Institute of Biology Leiden coordinates the training.

The main goal of the research described in this thesis was the development of new photoactivated chemotherapy (PACT) ruthenium(II) complexes bearing a non-toxic photolabile ligand.

PhD Defence

Chemist Roxanne Kieltyka has received an ERC Starting Grant of 2 million euros. In her lab, she creates gels that mimic the instructive material that supports cells in our body. With the grant, she aims to make these gels stiff and tough, and to create a bio-printed miniature heart ventricle.

PhD Defence

PhD Defence

Tuberculosis is an infectious disease which is spreaded through the air. It is caused by Mycobacterium tuberculosis and it led 1.7 million people to death in 2016. This mortarlity rate is concentrated in developing countries such as Indonesia, Philippines, Pakistan, and South Africa. These numbers make…

Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)

What are the mysteries behind soft condensed matter?

This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.