Promotor: E. Bouwman, Co-Promotor: S. Bonnet

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

Promotor: M.A.G.J. Orrit

Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease progression and treatment response. A Systems Medicine approach, based on computational…

Promotores: H. Schiessel, G.T. Barkema

PhD Defence

The aim of this thesis is to develop and study a robust and adaptable scaffold for supramolecular polymer self-assembly in water.

The faculty coordinators ensure that faculties and programmes make plans to innovate education. They also coordinate the implementation of these plans.

Social and Behavioural Sciences, Psychology

In my research, I focus on cooperation, social dilemmas, tacit coordination, uncertainty, sanctions and trust.

This month, a paper was published in Nanoscale by scientists from Dr. Alireza Mashaghi group at the Systems Biomedicine and Pharmacology Division in collaboration with the group of Dr. Sander Tans from TU Delft/AMOLF. In this paper, the authors studied how nanoscale spatial confinement affects the fold…

This dissertation provides a systematic description of English and Afrikaans verbal pseudo-coordination and a formal analysis couched in the Minimalist program.

Governments are increasingly facilitating the roll-out of so-called “smart meters”, a technology for measuring energy consumption that are able to transmit and receive data using a form of electronic communication. However, implementation has been slow or even stalled.

Co-ordination Action for Innovation in Life-Cycle Analysis for Sustainability: deepening, broadening and leaping forward the LCA methodology.

There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…

Molecules are extremely hard to see in visible light, especially without using fluorescence. Leiden physicists have now made their optical technique sensitive enough to image the molecules of their interest in all sizes. Publication in Nanoletters.

A full overview of MCBIM PhD theses.

Are you passionate about sustainability? Do you see opportunities to make Leiden University more sustainable? Are you able to inspire, engage and empower both students and staff? This is your chance to contribute!

Source: Bioorg Med Chem, Volume 23, Issue 14, pp. 4034-49 (2015)

The group of Dr. Roxanne Kieltyka designs and synthesizes molecules that self-assemble into polymeric materials using specific non-covalent interactions. These substrates can be used for numerous applications in medicine ranging from disease detection to cell delivery depending on the (bio)molecular…

The research described in this thesis focused on the preparation of S/N functionalized carbene ligands and their transition metal complexes, and the exploration of their application as electrocatalysts for proton reduction.

This thesis describes the design, characterization and application of dextran based crosslinked network.

The focus of our theoretical research is understanding the behaviour of soft condensed matter, physical matter which is deformed or structurally altered by thermal fluctuations or small stresses.

While colloidal aggregates are often undesirable due to their random shapes, we exploit them as a starting point to synthesize patchy particles.

PhD Defence

The Delivery of Biotherapeutics research group is led by Prof. Matthias Barz and focusses on the synthesis and characterization of polypept(o)ids and their application in nanomedicine to improve existing therapies or enable novel diagnostic or therapeutic approaches.

When does it rain when air is oversaturated with moisture? How does an infection spread among the population? The problems that mathematician Professor Frank den Hollander tries to solve come from physics, chemistry and biology.

Vitelli

Long sugar chains from plant cell walls are an attractive feedstock for industry, but they are recalcitrant to break down. Many fungal species, however, easily degrade polysaccharides with hydrolytic enzymes. These enzymes are of high interest for industrial use. Sybrin Schröder and Casper de Boer developed…

A common assumption in chemistry is that the coordination number of a catalyst's surface determines the reactivity of the reaction it catalyses. Strikingly, Leiden chemists have now proven that this is not true for nature’s most simple chemical reaction: the dissociation of hydrogen. The researchers…

The new project INFLANET will train young scientists in Europe to become experts in inflammation research. Professor Annemarie Meijer from the Institute of Biology Leiden coordinates the training.

PhD Defence

The main goal of the research described in this thesis was the development of new photoactivated chemotherapy (PACT) ruthenium(II) complexes bearing a non-toxic photolabile ligand.

Chemist Roxanne Kieltyka has received an ERC Starting Grant of 2 million euros. In her lab, she creates gels that mimic the instructive material that supports cells in our body. With the grant, she aims to make these gels stiff and tough, and to create a bio-printed miniature heart ventricle.

PhD Defence

PhD Defence

Many researchers of the Faculty of Science are members of a research school related to their area of expertise. Research schools aim at collaboration of researchers from different faculties in the same university (interfaculty schools) or in different universities (interuniversity schools).

Tuberculosis is an infectious disease which is spreaded through the air. It is caused by Mycobacterium tuberculosis and it led 1.7 million people to death in 2016. This mortarlity rate is concentrated in developing countries such as Indonesia, Philippines, Pakistan, and South Africa. These numbers make…

We investigate emergent structures and dynamics of soft materials self-assembled from microscopic constituents.

This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.

Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)

In April 2018, Melanie Fink was elected as a member of the Coordinating Committee of the ESIL Interest Group ‘The EU as a Global Actor’. For the next four years, she will work in that function alongside Christine Kaddous (University of Geneva), Anne Thies (University of Reading), and Ramses Wessel (University…

Metal-based prodrugs based on ruthenium(II) polypyridyl complexes have proven to be very suitable for application in both photodynamic therapy (PDT) and photo-activated chemotherapy (PACT).

On October 20th, the advanced International Children’s Rights master program and the Leiden Institute of Immigration Law co-organized a public lecture and Q&A session with Ms. Margaret Tuite, the European Commission Coordinator for the Rights of the Child.