Promotor: Peter Stevenhagen

This thesis has three main parts. The first part gives an algorithm to compute Hilbert modular polynomials for ordinary abelian varieties with maximal real multiplication. Hilbert modular polynomials of a given level b give a way of finding all of the abelian varieties that are b-isogeneous to any given…

Promotor: Peter Stevenhagen

To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.

Promotores: P. Stevenhagen, A. Enge Co-Promotor: T.C. Streng

This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.

For many system in statistical physics the microcanonical and canonical ensemble are equivalent in the thermodynamic limit, but not for all.

Latent variable modeling of students' solution strategies and performance

Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

Complex systems can be characterized as systems in which multiple components interact with each other, often in non-linear ways. The main goal of this research will be to investigate if and how the international tax system can be defined and modelled as a complex system. Approaching the international…

Promotor: J.W.M. Frenken, Co-Promotor: R. Felici

What invertebrates are available to feed nestlings in an agricultural landscape of varied complexity?

The goal of the project is the development of stream mining techniques for complex patterns such as graphs. We will try to extend the existing state-of-the-art techniques into two, orthogonal directions: on the one hand, the mining of more complex patterns in streams, such as sequential patterns and…

Promotor: E. Bouwman, Co-promotor: S. Bonnet

This thesis is comprised of three chapters covering the theme of studying semistable varieties by looking at their dual combinatorial objects.

Essays in Archaeology and Assyriology Dedicated to Diederik J.W. Meijer in Honour of his 65th Birthday

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In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.

Issues such as climate change, the depletion of natural resources or social inequality are too complex to be addressed from a single scientific discipline or by a single country. Leiden University has the expertise to bring the resolution of these enormous problems a small step closer.

This thesis proposes multiple paths towards the development of a performance practice in Computer Music.

The Leiden Complex Networks Network (LCN2) aims at bringing together scientists from different disciplines, based on a common interest in both theoretical models and empirical analyses of networks and graphs.

Andrea Giolai defended his thesis on 3 May 2017.

Three at the same time: a ligation strategy combining tetrazine–norbornene cycloaddition, Staudinger–Bertozzi ligation, and copper(I)-catalyzed click reaction was used to label the three catalytic activities of the proteasome simultaneously in a single experiment. The orthogonality of the three ligation…

This thesis describes the genetic and prokaryotic diversity of giant barrel sponges.

We study the physics of a broad range of biological and soft materials

The main objective of this thesis was to develop clinically relevant survival models for patients with high-grade soft tissue sarcoma of the extremities, in particular the development and validation of prediction models for use in clinical practice.

The complexity of an intelligence problem determines to a great extent the certainty that can be provided by intelligence and security services.

In this thesis, the researcher developed a nanosystem based on the metallophilic Interaction between cyclometalated complexes.

Promotor: E. Bouwman Co-Promotor: S. Bonnet

Hetterscheid

From surface science towards industrial practice using high-pressure scanning tunneling microscopy.

In vitro disease models play a fundamental role in drug research. They enable the systemic identification and validation of disease mechanisms and the discovery of possible drug targets. However, more than often, drug candidates that are identified in vitro fail in the later clinical stages of drug…

Promotor: Prof.dr. M. Ubbink

The aim of this project is to determine in which cases uncertainty statements resulting from a Bayesian statistical analysis can be trusted.

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.

Social Aspects of Space in the Configurational Architecture of Frankish Castles in the Holy Land, 1099-1291

I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.

The overall aim of the project is to investigate interests and their development over time in a daily life context, with particular attention for the transition from late secondary to post secondary education, and from late post secondary education to early career.

The Vrijthof excavations (1969-1970)

Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

Promotor: Prof.dr. H.V.J. Linnartz, Co-Promotores: S. Ioppolo, H.M. Cuppen

Promotor: G.A. van der Marel, Co-promotor: D.C. Codée

Promotor: Prof.dr. E. Bouwman

Promotor: J.W.M. Frenken Co-Promotores: I.M.N. Groot; L.B.F. Juurlink

We will study how inoculation of former arable land with soil (including the microbiome, soil fauna and seeds/rhizomes of ground flora) from old forests along with planting targeted tree species mixtures will improve productivity and more rapidly restore forest-adapted communities and ulttimately result…

This thesis consists of three chapters, the first two of which concern division points of elements of the multiplicative group of a number field.