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On a structural level, the properties featured by a majority of mechanical metamaterials can be ascribed to the finite number of soft internal degrees-of freedom allowing for low-energy deformations.

Mechanical interactions between cells and their environment play an important role in many biological processes.

Mechanisms fro drug resistance

Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf

In what ways can a photographic practice act as a means to confront, or even undo, the various material properties of atmospheric enclosure that so clearly put our relationship with our environment under pressure? Is it possible to devise a set of critical and artistic strategies to comprehend the ways…

What is the Fine Mechanical Department?

Bouwmeester

Promotor: F.P. Israel, Co-Promoter: R. Meijerink

Mechanical metamaterials are man-made materials which derive their unusual properties from their structure rather than their composition.

The four possible segments A, T, C and G that link together to form DNA molecules, and with their ordering encode genetic information, are not only different in name, but also in their physical and chemical properties.

We investigate the physics and design of mechanical metamaterial, intricately sculpted materials with properties set by their architecture.

We are interested in understanding the mechanics of soft materials, of which biological materials are prominent examples.

Part of ‘Moralising Misfortune: A Comparative Anthropology of Commercial Insurance’, an ERC Consolidator project of Erik Bähre.

How do you fit two meters of DNA in a tiny compartment and at the same time are able to access the right parts of it at the right times?

To what extent does the Law Ombudsperson for Children achieve its goals as intended by the legislator when introducing the law?

Bacterial biocatalysis constitutes a sustainable alternative for high-value chemicals production by enabling the utilization of renewable feedstocks.

The applications of studying the early development of insects range from agriculture to material science.

Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

Adverse drug reactions (ADRs) remain one of the major reasons for patient mortality and (early) drug withdrawal. Currently, different in vivo and in vitro models are used to assess the toxic potential of drugs in the pre-clinical phase. Unfortunately, the predictive value of this model does not fit…

We aim to unravel the molecular mechanisms involved in the transformation of eukaryotic cells by Agrobacterium.

We explore the possibilities to combine magnetic resonance techniques with atomic force microscopy together in a single microscope: the MRI-AFM, also called Magnetic Resonance Force Microscopy (MRFM).

Beenakker

Promotor: M.L. van Hecke

In this project we study the properties of statistical- and rule-learning mechanisms in relation to the acquisition and evolution of language. We ask to what extent these mechanisms are unique to humans - or to human language - by comparing the acquisition of vocal structure in two species: humans (infants)…

My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.

A central and much debated topic in the study of language acquisition concerns the nature of the learning mechanisms that are required. Are the computational and learning mechanisms that guide learning about language structure special and specific to language or humans?

Despite an increased EU role in the preparedness, monitoring and coordination of health emergencies over the past two decades, Member States’ responses to the first wave of COVID-19 were surprisingly uncoordinated. In light of calls to improve cooperation regarding future health emergencies, this article…

Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa

Promotor: G.P. van Wezel

How presence, abundance and enzymatic activities of AM and EM fungi differently affect soil carbon sequestration processes?

Exploring the mechanism of targeted nanoparticle-mediated drug delivery using the zebrafish model

This thesis focuses on the role of chemokine receptors CXCR3 and CCR2 in the inflammatory process and infection control using the zebrafish model.

We investigate how radiation pressure can be used to influence the mechanical motion of a micro-mirror suspended from springs.

Prostate cancer (PCa) is one of the most prevalent cancer in males.

Promotor: Prof.dr. J. den Hertog

Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

Promotor: B. van de Water

On October 31st, Margarita Gulian succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Margarita on this great result.

The “harpe organisée”, 1720-1840: Rediscovering the lost pedal techniques on harps with a single-action pedal mechanism, is the title of Maria Christina Cleary's PhD thesis. This is the first monographic study on harp pedal techniques, tracing the historical way to pedal on the early pedal harps with…

Source: Mediators Inflamm (2014)

To argue that people can control the relative contributions of goal-driven and stimulus-driven processes to decision-making and action selection.

The mechanism of the electrochemical reduction of dioxygen by a mononuclear pyridylalkylamine copper complex was investigated (see picture). It was shown that in neutral aqueous solution dioxygen undergoes stepwise reduction, wherein hydrogen peroxide plays a key role. The rate constants determined…

Promotor: A.P. IJzerman

Cars are equipped with catalysts to disarm toxic exhaust gases. Platinum plays an important role there. Leiden physicists and chemists have now for the first time seen the mechanism behind a platinum catalyst. With a fundamental understanding of the process, scientists can use this rare material more…

Leiden University organizes a course on quantum mechanics for high school Physics teachers. As the curriculum gains a new quantum component, the university enables teachers to give the best possible guidance to their students.

Promotor: Prof.dr. M. Danhof, Co-promotor: E.C.M. de Lange

Special amplifying agents can make MRI scanners and NMR techniques hundreds of times more sensitive. Leiden physicists have now found a method to test their efficiency. More sensitive MRI scans could for example improve our understanding of cystic fibrosis or Parkinson’s disease. Publication in PCCP…