What are the principles of genome folding and dynamics in bacteria?

The facility develops and applies advanced, high-throughput methods for genomic research.

How did toxin genes evolve from harmless physiological genes?

The four possible segments A, T, C and G that link together to form DNA molecules, and with their ordering encode genetic information, are not only different in name, but also in their physical and chemical properties.

The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine.

PhD defence

Is translocation of nucleases possible via Agrobacterium T4SS and is it efficient enough for mutagenesis?

Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.

Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.

Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

The research is aimed at development of an efficient gene targeting method that allows controlled integration of DNA at a preselected site in the Trichoderma genome.

Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.

Can the venom of snakes, scorpions and other animals be sources of new antibiotics?

Leiden evolutionary biologist Maurijn van der Zee has co-operated on an enormous international project to describe the genetic material of the pea aphid Acyrthosiphon pisum. The more than 100 authors involved in the project have published their findings in the online magazine PLoS Biology.

CompaRe aims to be a hub in a global network on comparative regional integration. For regional integration is key to meeting the challenges of our globalizing world.

Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.

Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal

Promotor: Prof.dr. T. Hankemeier, Co-promotor: R.J. Vreeken

Common challenge: unique circumstances

All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).

Leiden researcher Dr Ben Zonneveld has determined the size of the genome - the amount of DNA per nucleus - of wild tulips. His conclusion is that there are more than 87 wild species. Various possibly new species have been discovered.

The master's programme Comparative Criminal Justice at Leiden University focuses on criminology, criminal law and their mutual relationship. The programme offers an international comparative perspective, analysing criminal justice systems, legislation and policies in common law and civil law countri…

Are you thinking about studying Comparative Criminal Justice? Learn more and watch the videos

The research programme Descriptive and Comparative Linguistics brings together LUCL researchers who focus mainly on descriptive and comparative linguistics.

The ‘Locke drawings’ collection and the representation of Brazilian native peoples in global perspective

PhD defence

Reconstructing language history through the study of language change.

Reconstructing language history and prehistory in the context of the Indo-European language family.

This Global and Comparative Philosophy master’s programme is unique in Europe. It offers comparative perspectives from around the world that will enable you to be part of the next generation of thinkers: someone studying and shaping philosophy for a globalised 21st century.

Almost all languages of Europe and of a large part of western Asia belong to a single language family, which is called Indo-European, and which includes modern languages like English, Dutch, Russian, Farsi, but also ancient ones like Ancient Greek, Latin, Hittite and Sanskrit.

How do you decide which master's programme suits you best?

Study information, Online Experience

This study aims to examine how South Korea (hereafter, Korea) and Japan, two neighboring countries in Northeast Asia, have been responding to and mitigating the spread of COVID-19.

This Philosophy: Global and Comparative Perspectives bachelor's programme is unique in that it offers comparative perspectives from around the world that will enable you to be part of the next generation of thinkers, someone studying and shaping philosophy for a globalised 21st century.

An international team from the Netherlands, France, Norway and Austria demonstrate how new sequencing technologies can be used to efficiently generate the genome, DNA, sequence of an endangered animal, the European Eel.

A theoretical project on the insights gained by human (including infant), nonhuman animal and computational studies on artificial grammar learning; identifying the critical questions for future research by developing novel experimental and computational approaches to address these issues.

‘It's where disciplines intersect that the most exciting scientific questions arise.' This was the message given by John van Noort, Professor of Biophysics, in his inaugural lecture. His own research is at the interface between biology and physics. Inaugural lecture 23 April.

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

We study expressions of emotion and social decision making across species.

This project contests the assumption of criminologists that gender differences in recorded crime are static over time and that women are in general less likely to commit a crime than men.

On March 21 2018, a study was published in Nature, co-authored by Professor M. Soressi from the Faculty of Archaeology of Leiden University, announcing the sequencing of five new Neandertals, raising the number of high-coverage sequenced Neandertals from two to seven. A tooth lost by a Neandertal woman…

DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.

Cwiertka wants to investigate how waste is produced and disposed of in modern East Asian society. With her research group she will be carrying out a comparative analysis on two levels: the international level (between China, Japan, South Korea and Taiwan) and the inter-regional level (between East Asia…

How has migration affected Irish and Italy society since 1945?

This thesis investigates the syntax of object marking in Sambaa and the Bantu languages in general, with particular focus on Swahili and Haya, as points of comparison.

Comparison across jurisdictions is one way of assessing the appropriateness of lethal force resulting from the actions of law enforcement agencies. This article sets out a vision for a global use of force monitor that can enable meaningful comparisons between law enforcement agencies. It examines some…

Freek Vonk and Mike Richardson, with many collaborators, have published two snake genomes in two parallel articles in the prestigious journal PNAS. Their new findings provide insight into the co-evolutionary arms race between predator and prey.