707 search results for “chromatin architecture” in the Public website
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Laura PlezierFaculty of Humanities
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The idea of the primitive hut
Subproject of
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Dissertation: existence and development of the European security architecture
On Thursday 15 April, Sabine Mengelberg, associate professor at the Faculty of Military Sciences of the Netherlands Defence Academy (NLDA), will defend her thesis on changes in European security architecture. Permanent Change? The Paths of Change of the European Security Organizations is the title of…
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NWO ECHO grant for research on fickle RNA production
Genes are active sometimes, and other times they remain dormant for a while. Leiden physicist John van Noort receives an NWO ECHO grant to find out how this happens.
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DNA folded in compliant helix
In an Advance Online Publication biophysicist John van Noort and others show using magnetic tweezers that DNA is folded in compliant helices of chromatin. This allows enzymes access to the DNA needed for gene expression. Van Noort's research group made the discovery in close partnership with researchers…
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Participants
The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).
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Guy LivingstonFaculty of Humanities
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Elizabeth den HartogFaculty of Humanities
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The role of the Arabidopsis AHL15/REJUVENATOR gene in developmental phase transitions
This thesis describes the functional analysis of the Arabidopsis AHL15 gene.
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DNA repair in chromatin: the cancer connection
Lecture
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Computational, biochemical, and NMR-driven structural studies on histone variant H2A.B
Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.
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Helmut Schiessel Group (Theoretical Physics of Life Processes)
The group Theoretical Physics of Life Processes, led by Helmut Schiessel, focuses on the physics of chromatin, the DNA-protein complex that fills the nuclei of eukaryotic cells.
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Get to know Roberta D'Alessandro and discover the architecture of language
How does language work and how do we learn a language? The more we know about language, the better we can understand how people interpret the world in words. Roberta D'Alessandro carries out research on the architecture of language. There is now a dossier about her work online.
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Research
Research at the Macromolecular Biochemistry group is comprised of the following research themes:
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Antoinette HuijbersFaculteit Archeologie
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Valentina AzzaràFaculteit Archeologie
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Roos StolkerFaculty Governance and Global Affairs
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Hans TheunissenFaculty of Humanities
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Lithic Technology, Social Agency and Cultural Interaction in the Bronze Age Aegean
LiTechAe: Percussive stone tools related to stone masonry techniques seen through experimentation and use-wear analysis.
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Alexander GeurdsFaculteit Archeologie
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Packaging and accessing DNA molecules
Our DNA molecules are packaged by proteins in compact structures. The aim of this project is to understand how modern gene editing techniques nevertheless get access to their target in the DNA.
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Human genetics, in particular chromatin and DNA repair
Inaugural Lecture
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Elevated minds: The Sublime in the public arts in 17th-century Paris and Amsterdam
The aim of this project is to study the influence of Longinus’s treatise ‘On the sublime’ on practice and theory of architecture and theatre in seventeenth-century Paris and Amsterdam.
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Diederik SmitFaculty of Humanities
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Marie-leen Ryckaert
Faculty Governance and Global Affairs
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Dynamic organization of bacterial chromatin by DNA bridging proteins
PhD Defence
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Modifying the modifier: Discovering mechanisms of SMCHD1 mediated chromatin repression
PhD Defence
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The Role of Linker DNA in Chromatin Fibers
PhD Defence
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Chromatin modifiers in DNA repair and human disease
PhD Defence
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Collaborations
Find out more about our national and international research collaborations.
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SETinSTONE
A retrospective impact assessment of human and environmental resource usage in Late Bronze Age Mycenaean Monumental Architecture, Greece
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Ann BrysbaertFaculteit Archeologie
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Alexander DencherFaculty of Humanities
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Chemical Biology Lecture: PARP activation upon DNA damage induces chromatin dynamics
Lecture
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Publications
Relevant publications of the CIGR participants.
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Our approach
Our group operates at the cross-roads of different disciplines: molecular and cellular microbiology, biochemistry, structural biology and biophysics. The group harbors expertise in a multitude of molecular and cellular approaches including:
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Chemical Biology Lecture: The mechanism of ATP-dependent chromatin remodeling
Lecture
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Lyndsey Housden
Lyndsey Housden teaches in the Interactive/Media/Design department at the Royal Academy of Art (KABK), The Hague. She is a researcher and artist, working with interactive and haptic installations, spatial design and interdisciplinary projects for exhibitions, theatre, and festivals.
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Cosmological interpretation of architecture
PhD Defence
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Architectural terracottas from Akragas
PhD Defence
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Social Technology of (mudbrick) Architecture
Lecture
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Exposition MEMORY: Architecture of Belonging
PhD Defence, Artistic work associated with Public Defense
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the equilibrium between ERa-activation, epigenetic alterations and chromatin integrity
PhD Defence
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Nucleosome stacking in chromatin fibers probed with single-molecule force- and torque-spectroscopy
PhD Defence
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Responding to environmental cues: The adaptive qualities of chromatin compaction proteins
PhD Defence
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The Salm story: the forgotten architects of the Netherlands
Music venue Paradiso, the Keizersgracht Church and the Artis Zoo’s aquarium: these buildings all owe their design to architects Gerlof Bartholomeus Salm and Abraham Salm. Remco van der Kuijp researched the place of father and son in architectural history. PhD defence on 25 March.
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Biological and Soft Matter Physics
Research groups in the Biological & Soft Matter Programme unravel mechanisms in biological processes and develop novel bio-inspired soft materials.
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A molecular journey : tales of sublimating ices from hot cores to comets
The thesis explores how interstellar chemistry evolves as a function of time and changing physical architectures during the formation of stars.
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Shocks and failure in fragile matter
Vitelli
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Picturing Silence: interpreting the musical experience of silence through visual representation
If, as the works of John Cage suggest, there is “no such thing as silence,” then what are the markers that show us we are experiencing silence? - what are the performative cues during musical silence? - what are the auditory and visual bookends of silence in performance, i.e. what anticipates and…