Promotor: Prof.dr. T. Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto

New technology offers many new possibilities for research, such as on dementia. ‘Organ-on-a-chip’ is a new technology in which small bits of organ are grown out of stem cells on a small plastic plate. A small piece of blood vessel, heart or nerve offers many new possibilities for research, such as…

A collaboration of physicists and chemists organized the LEELIS conference on new computer chip technology in Amsterdam on 10-11 November. Leiden physicist Joost Frenken is director of the organizing institute ARCNL.

The article that was published on 21 January 2020 claims that chip maker ASML wants to be able to export to China but has been unable to obtain the necessary permits. Last summer, the application by the Dutch Ministry of Foreign Affairs (BZ) was suddenly frozen after pressure from the USA, according…

Our world is shrinking, or at least our electronic devices are. From PCs to mobile phones: everything is smaller and thinner. The smaller the chip, the better it can conduct electricity and pass on information.

In multi/many-core System-on-Chips (SoCs), the performance is almost linearly scaling with the number of processing elements.

The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

With a pioneering project like the quantum computer, it’s a good idea not to place all your bets on a single horse. In Leiden’s Quantum Optics research group, instead of working on a Majorana-based qubit, people are working on a qubit based on an ‘artificial atom’. If that becomes the basis of the quantum…

A couple of years ago, theoretical physicist Carlo Beenakker tracked down the Majorana particles and inspired Leo Kouwenhoven from TU Delft to try to create them in a superconducting nano-structure. He succeeded in doing so in 2012, and the news made headlines around the world. But a lot of work still…

This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…

The CMCB brings together a diverse range of unique expertise in microbial cell biology. Members of the CMCB investigate both model and non-model organisms, bacteria and archaea, pathogens and non-pathogens.

Truth is stranger than fiction. In 1997 Juan Maldaceña discovered a remarkable dictionary that translates equation for equation the physics of black holes in string theory into the more conventional physics of quantum mechanics of interacting particles. The remarkable possibility exists that…

Leiden physicists found a surprising interaction between electrons and a resist layer. The resist appears to charge and discharge due to incoming electrons. Publication in Physical Review Letters.

Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.

The Editorial Board of Perspectives on Terrorism currently consists of 26 experienced researchers.

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

Although Ebola is a virus with significant fatality rates, we still lack effective countermeasures to battle it. To change this, Alireza Mashaghi and his colleagues from the Leiden Academic Centre for Drug Research have successfully developed an organ-on-a-chip model that imitates the most dangerous…

Can a proposed new radiofrequency approach to graphene biosensors lead to groundbreaking changes in genome mapping?

The Quantitative Pharmacology group headed by Coen van Hasselt focusses on the application of state-of-the-art quantitative pharmacological mathematical and statistical (pharmacometrics) modeling combined with systems biology modeling approaches, to characterize biomarkers for of disease and treatment…

This thesis focuses on addressing four research problems in designing embedded streaming systems.

The Dutch-Japanese made DESHIMA instrument has passed its first practical tests when measuring the distances and ages of distant galaxies. The core of the instrument is a chip the size of two euro coins that measures 49 shades of far infrared light. The developers of the spectrometer publish the results…

Lecture, Studium Generale

Featuring the world’s first neural synthesizer, artist Guy Ben-Ary and his collaborators will perform at the TodaysArt Festival in The Hague on 21 September. For this performance, he collaborated with the lab of Erik Danen to transform neural stem cells into neural networks on a chip.

Finding solutions for economically and socially relevant problems in digital data security. That is what Nele Mentens, Professor of Applied Cryptography & Data Security at the Leiden Institute of Advanced Computer Science (LIACS), wants to achieve. On 1 June she was appointed to contribute to the institute…

The race to build the first quantum computer is still ongoing, but Morten Bakker has made big step forward in that process with qubits. A qubit is a unit of quantum information that can be produced in large numbers on chips. Qubits capable of exchanging photons (light particles) could be used in the…

In the master’s programme in Archaeology, you can follow courses on the archaeology of the Near East, deepening your understanding of this region’s fascinating past.

Organ-on-chip technology is used in drug research and customized treatments for patients. Research Institutes and industry join forces within the Institute for human Organ and Disease Model Technologies (hDMT) that was officially launched on May 18. Combining facilities, people and expertise will allow…

SRON Netherlands Institute for Space Research is moving. In 2021, the Utrecht branch will settle in South Holland. Assistant professor at TU Delft, Akira Endo leads a project that builds a state-of-the-art instrument for astronomical research. ‘SRON is the key to go from proof-of-concept to a science-grade…

It sounds futuristic, but it is possible: the creation of miniature organs of patients in order to study them and see how diseases develop and can be treated. This is what researchers from the LUMC, Twente University (UT), UMCG, TU Delft and the Hubrecht Institute hope to achieve in the next ten years…

For medical research, researchers often recreate tissue in the lab. Organ-on-a-chip technology emulates organs, right down to the blood that flows through them, thus creating a realistic test model for drugs or research into disease processes. Researchers from the LUMC are coordinating an NWO Gravitation…

Superconducting devices such as SQUIDS (Superconducting Quantum Interferometry Device) can perform ultra-sensitive measurements of magnetic fields. Leiden physicsts invented a method to 3D-print these and other superconducting devices in minutes.

Physics professor Jan Aarts starts a collaboration with chip manufacturer Intel to perform fundamental research in low-power, cryogenic computing.

Research conducted at Leiden has established that guts-on-chips respond in the same way to aspirin as real human organs do. This is a sign that these model organs are good predictors of the effect of medical drugs on the human body. Publication in Nature Communications on 15 August.

Physics and Engineering Approaches to Biomedicine and Pharmacology

The need for novel drugs as well as innovations in their development and application is as urgent as ever. Below we present our vision , mission, and our key research areas.

The better teaching is for pupils and students, the more solid the basis will be that we give them for their future careers. This type of teaching requires strong instructors and insight into the best ways in which pupils can be supported, and research at Leiden University is making a contribution in…

The Wadi al Jizzi Archaeological Project is a systematic and long term archaeological surface survey project, investigating the rich archaeological heritage of the Wadi al Jizzi region (Oman) from the Paleolithic until the early Modern period.

Mashaghi lab conducts research at the interface of physics, engineering and biomedicine. We develop and use theoretical and experimental approaches to address basic and applied research problems.

Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…

Vera Meester has won the annual Physics Image Award 2016, with her photo of 'smiling' colloids. The Volkskrant published the picture as Image of the Week.

Immerse yourself: read books, listen to podcasts and watch films about racism, discrimination and the colonial past.

The Centre for Innovation has launched a new podcast series called What if Education… In each episode, the host Monika Theron invites students, teachers and experts to think differently about education.

As fruit and vegetables ripen, ethylene gas is released. Ethylene also influences the speed at which they ripen. Chemist Tom van Dijkman studied how small and inexpensive sensors can be made that measure ethylene concentrations during transportation. PhD defence 12 May 2016.

Electric noise can be useful for scientists but inconvenient for chip manufacturers. They do share a wish to predict the amount of noise. PhD student Sumit Tewari overturns a century-old law relating noise to current. He defends his thesis on March 27th.

Theoretical physicist Carlo Beenakker has been awarded a €2m Advanced Grant by the European Research Council (ERC). He will use this to try to create the ideal building blocks for a quantum computer: ‘braided’ Majorana fermions. An ambitious project that may just lead to a major breakthrough.

NWO has awarded a Vidi subsidy to a total of 89 young and innovative researchers. Leiden researchers have won twelve of these subsidies and three subsidies have gone to the LUMC. Each researcher will receive up to 800,000 euro to develop a particular research theme or to set up a research group.

By analysing the metabolism using big data techniques, we can identify health risks at an earlier stage. Thomas Hankemeier, professor of Analytical Biosciences at the Leiden Academic Centre for Drug Research, explains how that works.

As a prelude to the Night of Discoveries, an Afternoon of Discoveries will be held in Leiden on 21 September for children from the age of eight. Researchers will tell exciting tales and the children will get to do experiments.